JP2025512066A5 - - Google Patents

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Publication number
JP2025512066A5
JP2025512066A5 JP2024560463A JP2024560463A JP2025512066A5 JP 2025512066 A5 JP2025512066 A5 JP 2025512066A5 JP 2024560463 A JP2024560463 A JP 2024560463A JP 2024560463 A JP2024560463 A JP 2024560463A JP 2025512066 A5 JP2025512066 A5 JP 2025512066A5
Authority
JP
Japan
Prior art keywords
mrna agent
human
cells
stem cells
evs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024560463A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025512066A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2023/000204 external-priority patent/WO2023199113A1/en
Publication of JP2025512066A publication Critical patent/JP2025512066A/ja
Publication of JP2025512066A5 publication Critical patent/JP2025512066A5/ja
Pending legal-status Critical Current

Links

JP2024560463A 2022-04-15 2023-04-13 エキソソームを介したmRNA剤の送達のための組成物及び方法 Pending JP2025512066A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263331532P 2022-04-15 2022-04-15
US63/331,532 2022-04-15
PCT/IB2023/000204 WO2023199113A1 (en) 2022-04-15 2023-04-13 COMPOSITIONS AND METHODS FOR EXOSOME-MEDIATED DELIVERY OF mRNA AGENTS

Publications (2)

Publication Number Publication Date
JP2025512066A JP2025512066A (ja) 2025-04-16
JP2025512066A5 true JP2025512066A5 (https=) 2026-04-17

Family

ID=86771485

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024560463A Pending JP2025512066A (ja) 2022-04-15 2023-04-13 エキソソームを介したmRNA剤の送達のための組成物及び方法

Country Status (8)

Country Link
US (1) US20230330264A1 (https=)
EP (1) EP4507701A1 (https=)
JP (1) JP2025512066A (https=)
KR (1) KR20250004778A (https=)
AU (1) AU2023254488A1 (https=)
CA (1) CA3247667A1 (https=)
IL (1) IL316370A (https=)
WO (1) WO2023199113A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026017857A1 (en) 2024-07-18 2026-01-22 Smartcella Solutions Ab Treatment of osteoarthritis and/or rheumatoid arthritis with pro-chondrogenic and/or chondrocyte protective factors
WO2026017864A1 (en) 2024-07-18 2026-01-22 Smartcella Solutions Ab Treatment of osteoarthritis and/or rheumatoid arthritis with pro-chondrogenic and/or chondrocyte protective factors

Family Cites Families (27)

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US5486359A (en) 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5843780A (en) 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
US5994619A (en) 1996-04-01 1999-11-30 University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus Production of chimeric bovine or porcine animals using cultured inner cell mass cells
US5945577A (en) 1997-01-10 1999-08-31 University Of Massachusetts As Represented By Its Amherst Campus Cloning using donor nuclei from proliferating somatic cells
WO2003062404A1 (en) 2002-01-25 2003-07-31 Gamida-Cell Ltd. Methods of expanding stem and progenitor cells and expanded cell populations obtained thereby
EP2291213B1 (en) 2008-04-08 2015-08-19 SmartWise Sweden AB Endoluminal medical access device
WO2012004165A1 (en) 2010-07-08 2012-01-12 Karolinska Institutet Innovations Ab Novel endoluminal medical access device
EP2625189B1 (en) 2010-10-01 2018-06-27 ModernaTX, Inc. Engineered nucleic acids and methods of use thereof
WO2013103659A1 (en) 2012-01-04 2013-07-11 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Stabilizing rna by incorporating chain-terminating nucleosides at the 3'-terminus
SG11201408717XA (en) 2012-06-26 2015-02-27 Seraxis Inc Stem cells and pancreatic cells useful for the treatment of insulin-dependent diabetes mellitus
WO2014093924A1 (en) 2012-12-13 2014-06-19 Moderna Therapeutics, Inc. Modified nucleic acid molecules and uses thereof
PL2922554T3 (pl) 2012-11-26 2022-06-20 Modernatx, Inc. Na zmodyfikowany na końcach
US20160022840A1 (en) 2013-03-09 2016-01-28 Moderna Therapeutics, Inc. Heterologous untranslated regions for mrna
EP2968391A1 (en) 2013-03-13 2016-01-20 Moderna Therapeutics, Inc. Long-lived polynucleotide molecules
CN120796168A (zh) 2013-06-11 2025-10-17 哈佛学院校长同事会 SC-β细胞以及用于产生其的组合物和方法
MA40589A (fr) 2014-08-22 2017-06-28 Procella Therapeutics Ab Utilisation de jagged 1/frizzled 4 à titre de marqueurs de surface cellulaire pour isoler des cellules progénitrices ventriculaires cardiaques humaines
US10596200B2 (en) 2014-08-22 2020-03-24 Procella Therapeutics Ab Use of LIFR or FGFR3 as a cell surface marker for isolating human cardiac ventricular progenitor cells
WO2016100921A1 (en) 2014-12-18 2016-06-23 President And Fellows Of Harvard College METHODS FOR GENERATING STEM CELL-DERIVED β CELLS AND USES THEREOF
CN107614678B (zh) 2014-12-18 2021-04-30 哈佛学院校长同事会 干细胞来源的β细胞的产生方法及其使用方法
WO2016100898A1 (en) 2014-12-18 2016-06-23 President And Fellows Of Harvard College Serum-free in vitro directed differentiation protocol for generating stem cell-derived b cells and uses thereof
WO2016100925A1 (en) 2014-12-18 2016-06-23 President And Fellows Of Harvard College METHODS FOR GENERATING AUGMENTED STEM CELL-DERIVED β CELLS AND USES THEREOF
US11160834B2 (en) * 2015-04-28 2021-11-02 The Texas A&M University System Scalable production of standardized extracellular vesicles, extracellular vesicle preparations and uses thereof
EP3291822A1 (en) 2015-05-05 2018-03-14 Katholieke Universiteit Leuven Improved methods for pancreatic islet transplantation
CN107921148A (zh) 2015-05-08 2018-04-17 哈佛学院校长同事会 通用供体干细胞和相关方法
WO2017075708A1 (en) * 2015-11-05 2017-05-11 Exerkine Corporation Exosomes useful to treat cystic fibrosis
US10508263B2 (en) 2016-11-29 2019-12-17 Procella Therapeutics Ab Methods for isolating human cardiac ventricular progenitor cells
WO2019038587A1 (en) 2017-08-23 2019-02-28 Procella Therapeutics Ab USE OF NEUROPILIN-1 (NRP1) AS A CELL SURFACE MARKER FOR ISOLATING HUMAN CARDIAC VENTRICULAR PROGENITOR CELLS

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