JP2025509605A5 - - Google Patents

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Publication number
JP2025509605A5
JP2025509605A5 JP2024554856A JP2024554856A JP2025509605A5 JP 2025509605 A5 JP2025509605 A5 JP 2025509605A5 JP 2024554856 A JP2024554856 A JP 2024554856A JP 2024554856 A JP2024554856 A JP 2024554856A JP 2025509605 A5 JP2025509605 A5 JP 2025509605A5
Authority
JP
Japan
Prior art keywords
independently
alkyl
oligonucleotide
compound
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024554856A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025509605A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2023/052532 external-priority patent/WO2023175536A1/en
Publication of JP2025509605A publication Critical patent/JP2025509605A/ja
Publication of JP2025509605A5 publication Critical patent/JP2025509605A5/ja
Pending legal-status Critical Current

Links

JP2024554856A 2022-03-16 2023-03-15 Rnaの治療的送達のための脂質モノマー Pending JP2025509605A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263320689P 2022-03-16 2022-03-16
US63/320,689 2022-03-16
PCT/IB2023/052532 WO2023175536A1 (en) 2022-03-16 2023-03-15 Lipid monomers for therapeutic delivery of rna

Publications (2)

Publication Number Publication Date
JP2025509605A JP2025509605A (ja) 2025-04-11
JP2025509605A5 true JP2025509605A5 (https=) 2026-03-24

Family

ID=85781906

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024554856A Pending JP2025509605A (ja) 2022-03-16 2023-03-15 Rnaの治療的送達のための脂質モノマー

Country Status (7)

Country Link
JP (1) JP2025509605A (https=)
KR (1) KR20240164787A (https=)
CN (1) CN119213004A (https=)
AU (1) AU2023236844A1 (https=)
CA (1) CA3255238A1 (https=)
MX (1) MX2024011339A (https=)
WO (1) WO2023175536A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2025541262A (ja) * 2022-12-13 2025-12-18 上海拓界生物医薬科技有限公司 親油性モノマーを含むオリゴヌクレオチド及びその非肝臓送達における使用
AU2024351190A1 (en) * 2023-09-26 2026-03-26 Tuojie Biotech (Shanghai) Co., Ltd. Lipid-modified nucleic acid compound, and preparation method and use therefor
WO2025261376A1 (zh) * 2024-06-21 2025-12-26 北京炫景瑞医药科技有限公司 肝外递送配体及其缀合物
WO2026046355A1 (zh) * 2024-08-31 2026-03-05 齐鲁制药有限公司 dsRNA分子、药物组合物及其在肝外递送中的应用
CN119241620B (zh) * 2024-12-03 2025-04-08 羿美诚健(上海)生物医药有限公司 一种双链siRNA及其制备方法,药物组合物和用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3368933D1 (en) * 1982-09-21 1987-02-12 Fujisawa Pharmaceutical Co Phosphate derivatives, process for preparation thereof and pharmaceutical compositions of the same
EP3983077A4 (en) * 2019-06-17 2023-12-20 Alnylam Pharmaceuticals, Inc. DELIVERY OF OLIGONUCLEOTIDES TO THE STRIATUM
KR20230061389A (ko) * 2020-08-04 2023-05-08 다이서나 파마수이티컬, 인크. 올리고뉴클레오티드의 전신 전달

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