|
CA1340806C
(en)
|
1986-07-02 |
1999-11-02 |
James Merrill Prober |
Method, system and reagents for dna sequencing
|
|
US5374637A
(en)
|
1989-03-22 |
1994-12-20 |
Janssen Pharmaceutica N.V. |
N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives
|
|
US5846717A
(en)
|
1996-01-24 |
1998-12-08 |
Third Wave Technologies, Inc. |
Detection of nucleic acid sequences by invader-directed cleavage
|
|
SE9400522D0
(sv)
|
1994-02-16 |
1994-02-16 |
Ulf Landegren |
Method and reagent for detecting specific nucleotide sequences
|
|
US5750341A
(en)
*
|
1995-04-17 |
1998-05-12 |
Lynx Therapeutics, Inc. |
DNA sequencing by parallel oligonucleotide extensions
|
|
US5700642A
(en)
|
1995-05-22 |
1997-12-23 |
Sri International |
Oligonucleotide sizing using immobilized cleavable primers
|
|
US5854033A
(en)
|
1995-11-21 |
1998-12-29 |
Yale University |
Rolling circle replication reporter systems
|
|
US7432048B2
(en)
|
1996-11-29 |
2008-10-07 |
Third Wave Technologies, Inc. |
Reactions on a solid surface
|
|
US6284497B1
(en)
|
1998-04-09 |
2001-09-04 |
Trustees Of Boston University |
Nucleic acid arrays and methods of synthesis
|
|
US6235502B1
(en)
|
1998-09-18 |
2001-05-22 |
Molecular Staging Inc. |
Methods for selectively isolating DNA using rolling circle amplification
|
|
US7195872B2
(en)
|
2001-11-09 |
2007-03-27 |
3D Biosurfaces, Inc. |
High surface area substrates for microarrays and methods to make same
|
|
US20040110153A1
(en)
|
2002-12-10 |
2004-06-10 |
Affymetrix, Inc. |
Compleixity management of genomic DNA by semi-specific amplification
|
|
US6977153B2
(en)
|
2002-12-31 |
2005-12-20 |
Qiagen Gmbh |
Rolling circle amplification of RNA
|
|
US20090186343A1
(en)
|
2003-01-28 |
2009-07-23 |
Visigen Biotechnologies, Inc. |
Methods for preparing modified biomolecules, modified biomolecules and methods for using same
|
|
US8637650B2
(en)
|
2003-11-05 |
2014-01-28 |
Genovoxx Gmbh |
Macromolecular nucleotide compounds and methods for using the same
|
|
EP2789383B1
(en)
|
2004-01-07 |
2023-05-03 |
Illumina Cambridge Limited |
Molecular arrays
|
|
US7462452B2
(en)
|
2004-04-30 |
2008-12-09 |
Pacific Biosciences Of California, Inc. |
Field-switch sequencing
|
|
SE0401270D0
(sv)
|
2004-05-18 |
2004-05-18 |
Fredrik Dahl |
Method for amplifying specific nucleic acids in parallel
|
|
US7315019B2
(en)
|
2004-09-17 |
2008-01-01 |
Pacific Biosciences Of California, Inc. |
Arrays of optical confinements and uses thereof
|
|
US7170050B2
(en)
|
2004-09-17 |
2007-01-30 |
Pacific Biosciences Of California, Inc. |
Apparatus and methods for optical analysis of molecules
|
|
US7989166B2
(en)
|
2005-04-12 |
2011-08-02 |
In Situ Rcp A/S |
Circle probes and their use in the identification of biomolecules
|
|
DK1907571T3
(en)
|
2005-06-15 |
2017-08-21 |
Complete Genomics Inc |
NUCLEIC ACID ANALYSIS USING INCIDENTAL MIXTURES OF NON-OVERLAPPING FRAGMENTS
|
|
GB0514936D0
(en)
|
2005-07-20 |
2005-08-24 |
Solexa Ltd |
Preparation of templates for nucleic acid sequencing
|
|
US7405281B2
(en)
|
2005-09-29 |
2008-07-29 |
Pacific Biosciences Of California, Inc. |
Fluorescent nucleotide analogs and uses therefor
|
|
GB0522310D0
(en)
|
2005-11-01 |
2005-12-07 |
Solexa Ltd |
Methods of preparing libraries of template polynucleotides
|
|
WO2007120208A2
(en)
*
|
2005-11-14 |
2007-10-25 |
President And Fellows Of Harvard College |
Nanogrid rolling circle dna sequencing
|
|
US9328378B2
(en)
|
2006-07-31 |
2016-05-03 |
Illumina Cambridge Limited |
Method of library preparation avoiding the formation of adaptor dimers
|
|
US8932994B2
(en)
|
2006-08-24 |
2015-01-13 |
Illumina, Inc. |
Method for retaining even coverage of short insert libraries
|
|
WO2008070352A2
(en)
|
2006-10-27 |
2008-06-12 |
Complete Genomics, Inc. |
Efficient arrays of amplified polynucleotides
|
|
US7862999B2
(en)
|
2007-01-17 |
2011-01-04 |
Affymetrix, Inc. |
Multiplex targeted amplification using flap nuclease
|
|
EP2121983A2
(en)
|
2007-02-02 |
2009-11-25 |
Illumina Cambridge Limited |
Methods for indexing samples and sequencing multiple nucleotide templates
|
|
WO2009006907A1
(en)
|
2007-07-12 |
2009-01-15 |
In Situ Rcp A/S |
Padlock probe amplification methods
|
|
US8716190B2
(en)
|
2007-09-14 |
2014-05-06 |
Affymetrix, Inc. |
Amplification and analysis of selected targets on solid supports
|
|
US9388457B2
(en)
|
2007-09-14 |
2016-07-12 |
Affymetrix, Inc. |
Locus specific amplification using array probes
|
|
US7968702B2
(en)
|
2008-03-13 |
2011-06-28 |
Pacific Biosciences Of California, Inc. |
Labeled reactants and their uses
|
|
US7862344B2
(en)
|
2008-08-08 |
2011-01-04 |
Tyco Electronics Corporation |
Electrical connector having reversed differential pairs
|
|
US20100035252A1
(en)
*
|
2008-08-08 |
2010-02-11 |
Ion Torrent Systems Incorporated |
Methods for sequencing individual nucleic acids under tension
|
|
US9080211B2
(en)
|
2008-10-24 |
2015-07-14 |
Epicentre Technologies Corporation |
Transposon end compositions and methods for modifying nucleic acids
|
|
US8486630B2
(en)
*
|
2008-11-07 |
2013-07-16 |
Industrial Technology Research Institute |
Methods for accurate sequence data and modified base position determination
|
|
US8252910B2
(en)
|
2008-11-19 |
2012-08-28 |
Pacific Biosciences Of California, Inc. |
Modular nucleotide compositions and uses therefor
|
|
EP2607496B1
(en)
|
2008-12-23 |
2014-07-16 |
Illumina, Inc. |
Methods useful in nucleic acid sequencing protocols
|
|
WO2010117420A2
(en)
|
2009-03-30 |
2010-10-14 |
Pacific Biosciences Of California, Inc. |
Fret-labeled compounds and uses therefor
|
|
EP2419537B1
(en)
|
2009-04-13 |
2014-01-29 |
Somagenics, Inc. |
Methods and compositions for detection of small rnas
|
|
WO2012003374A2
(en)
|
2010-07-02 |
2012-01-05 |
The Board Of Trustees Of The Leland Stanford Junior University |
Targeted sequencing library preparation by genomic dna circularization
|
|
US8669374B2
(en)
|
2010-08-25 |
2014-03-11 |
Gene Shen |
Functionalized cyanine dyes (PEG)
|
|
US9029103B2
(en)
|
2010-08-27 |
2015-05-12 |
Illumina Cambridge Limited |
Methods for sequencing polynucleotides
|
|
EP2668273B9
(en)
|
2011-01-28 |
2017-03-29 |
Illumina, Inc. |
Oligonucleotide replacement for di-tagged and directional libraries
|
|
US20120196279A1
(en)
|
2011-02-02 |
2012-08-02 |
Pacific Biosciences Of California, Inc. |
Methods and compositions for nucleic acid sample preparation
|
|
WO2012108864A1
(en)
|
2011-02-08 |
2012-08-16 |
Illumina, Inc. |
Selective enrichment of nucleic acids
|
|
LT2825672T
(lt)
|
2012-03-13 |
2019-06-10 |
Swift Biosciences, Inc. |
Būdai ir kompozicijos, skirti valdomam pagal dydį substrato polinukleotidų homopolimeriniam uodegų formavimui su nukleorūgščių polimeraze
|
|
EP2929048B1
(en)
|
2012-12-06 |
2017-12-13 |
Agilent Technologies, Inc. |
Restriction enzyme-free target enrichment
|
|
EP2971130A4
(en)
|
2013-03-15 |
2016-10-05 |
Nugen Technologies Inc |
SEQUENTIAL SEQUENCING
|
|
US20140336063A1
(en)
|
2013-05-09 |
2014-11-13 |
Life Technologies Corporation |
Windowed Sequencing
|
|
CA2913236A1
(en)
|
2013-06-07 |
2014-12-11 |
Keygene N.V. |
Method for targeted sequencing
|
|
US9957291B2
(en)
|
2013-08-05 |
2018-05-01 |
Pacific Biosciences Of California, Inc. |
Protected fluorescent reagent compounds
|
|
EP3792366A1
(en)
|
2014-04-04 |
2021-03-17 |
Affymetrix, Inc. |
Improved compositions and methods for molecular inversion probe assays
|
|
ES2935285T3
(es)
|
2014-06-06 |
2023-03-03 |
Univ Cornell |
Método para identificación y enumeración de cambios en la secuencia de ácidos nucleicos, expresión, copia, o metilación de ADN, usando reacciones combinadas de nucleasa, ligasa, polimerasa y secuenciación
|
|
US11091810B2
(en)
|
2015-01-27 |
2021-08-17 |
BioSpyder Technologies, Inc. |
Focal gene expression profiling of stained FFPE tissues with spatial correlation to morphology
|
|
WO2016058517A1
(en)
|
2014-10-14 |
2016-04-21 |
Bgi Shenzhen Co., Limited |
Mate pair library construction
|
|
EP3303614B1
(en)
|
2015-05-29 |
2020-03-11 |
Illumina Cambridge Limited |
Enhanced utilization of surface primers in clusters
|
|
US10077470B2
(en)
|
2015-07-21 |
2018-09-18 |
Omniome, Inc. |
Nucleic acid sequencing methods and systems
|
|
WO2017087974A1
(en)
|
2015-11-20 |
2017-05-26 |
Pacific Biosciences Of California, Inc. |
Protected dye-labeled reagents
|
|
US10781483B2
(en)
|
2015-11-20 |
2020-09-22 |
Pacific Biosciences Of California, Inc. |
Labeled nucleotide analogs, reaction mixtures, and methods and systems for sequencing
|
|
US20170283864A1
(en)
|
2016-03-31 |
2017-10-05 |
Agilent Technologies, Inc. |
Use of transposase and y adapters to fragment and tag dna
|
|
WO2017177017A1
(en)
*
|
2016-04-07 |
2017-10-12 |
Omniome, Inc. |
Methods of quantifying target nucleic acids and identifying sequence variants
|
|
US10443098B2
(en)
|
2016-08-15 |
2019-10-15 |
Omniome, Inc. |
Method and system for sequencing nucleic acids
|
|
WO2018035170A1
(en)
|
2016-08-15 |
2018-02-22 |
Accuragen Holdings Limited |
Compositions and methods for detecting rare sequence variants
|
|
CN108203847B
(zh)
|
2016-12-16 |
2022-01-04 |
深圳华大智造科技股份有限公司 |
用于二代测序质量评估的文库、试剂及应用
|
|
CA3050241C
(en)
|
2017-01-20 |
2022-11-29 |
Omniome, Inc. |
Allele-specific capture of nucleic acids
|
|
KR102548274B1
(ko)
|
2017-03-20 |
2023-06-27 |
일루미나, 인코포레이티드 |
핵산 라이브러리를 제조하기 위한 방법 및 조성물
|
|
CN119824552A
(zh)
|
2017-05-01 |
2025-04-15 |
伊鲁米那股份有限公司 |
用于多重大规模平行测序的最佳索引序列
|
|
SG11201910070PA
(en)
|
2017-05-08 |
2019-11-28 |
Illumina Inc |
Universal short adapters for indexing of polynucleotide samples
|
|
JP2020532976A
(ja)
|
2017-09-14 |
2020-11-19 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
環状一本鎖dnaライブラリーを生成するための新規な方法
|
|
WO2019068797A1
(en)
|
2017-10-06 |
2019-04-11 |
F. Hoffmann-La Roche Ag |
CIRCULARIZATION METHODS FOR THE PREPARATION OF SAMPLE SAMPLES OF UNIQUE MOLECULES
|
|
CA3089756A1
(en)
|
2018-01-29 |
2019-08-01 |
St. Jude Children's Research Hospital, Inc. |
Method for nucleic acid amplification
|
|
CN111801427B
(zh)
*
|
2018-02-05 |
2023-12-05 |
豪夫迈·罗氏有限公司 |
用于单分子的单链环状dna模板的产生
|
|
EP3752832A1
(en)
|
2018-02-12 |
2020-12-23 |
10X Genomics, Inc. |
Methods characterizing multiple analytes from individual cells or cell populations
|
|
EP3775272B1
(en)
|
2018-04-02 |
2025-07-30 |
Enumera Molecular, Inc. |
Methods, systems, and compositions for counting nucleic acid molecules
|
|
PE20220773A1
(es)
|
2018-06-29 |
2022-05-16 |
Illumina Inc |
Cubetas de lectura
|
|
US11242512B2
(en)
|
2018-09-17 |
2022-02-08 |
Omniome, Inc. |
Engineered polymerases for improved sequencing
|
|
US20200149095A1
(en)
|
2018-11-14 |
2020-05-14 |
Element Biosciences, Inc. |
Low binding supports for improved solid-phase dna hybridization and amplification
|
|
US10768173B1
(en)
|
2019-09-06 |
2020-09-08 |
Element Biosciences, Inc. |
Multivalent binding composition for nucleic acid analysis
|
|
CN112739830A
(zh)
|
2018-12-18 |
2021-04-30 |
伊卢米纳剑桥有限公司 |
使用单一表面引物进行配对末端测序的方法和组合物
|
|
US11293061B2
(en)
*
|
2018-12-26 |
2022-04-05 |
Illumina Cambridge Limited |
Sequencing methods using nucleotides with 3′ AOM blocking group
|
|
US20200347443A1
(en)
|
2019-05-01 |
2020-11-05 |
Element Biosciences, Inc. |
Nucleic acid hybridization methods
|
|
WO2021061841A1
(en)
|
2019-09-23 |
2021-04-01 |
Element Biosciences, Inc. |
Methods for cellularly addressable nucleic acid sequencing
|
|
EP4114966B1
(en)
*
|
2020-03-03 |
2025-02-26 |
Pacific Biosciences Of California, Inc. |
Methods and compositions for sequencing double stranded nucleic acids
|
|
AU2021275128A1
(en)
|
2020-05-20 |
2023-01-19 |
Element Biosciences, Inc. |
Methods for paired-end sequencing library preparation
|
|
EP4189108A4
(en)
|
2020-07-31 |
2024-09-04 |
Element Biosciences, Inc. |
MULTIPLEX COVID-19 PADLOCK TEST
|
|
US12371743B2
(en)
|
2022-03-04 |
2025-07-29 |
Element Biosciences, Inc. |
Double-stranded splint adaptors and methods of use
|
|
US12359193B2
(en)
|
2022-03-04 |
2025-07-15 |
Element Biosciences, Inc. |
Single-stranded splint strands and methods of use
|
|
CA3196800A1
(en)
|
2020-10-30 |
2022-05-05 |
Element Biosciences, Inc. |
Reagents for massively parallel nucleic acid sequencing
|
|
WO2022232308A1
(en)
|
2021-04-27 |
2022-11-03 |
Singular Genomics Systems, Inc. |
High density sequencing and multiplexed priming
|
|
WO2022240764A1
(en)
|
2021-05-10 |
2022-11-17 |
Pacific Biosciences Of California, Inc. |
Single-molecule seeding and amplification on a surface
|
|
US11220707B1
(en)
|
2021-06-17 |
2022-01-11 |
Element Biosciences, Inc. |
Compositions and methods for pairwise sequencing
|
|
WO2022266470A1
(en)
|
2021-06-17 |
2022-12-22 |
Element Biosciences, Inc. |
Compositions and methods for pairwise sequencing
|
|
US11859241B2
(en)
|
2021-06-17 |
2024-01-02 |
Element Biosciences, Inc. |
Compositions and methods for pairwise sequencing
|
|
US20230193354A1
(en)
|
2021-06-17 |
2023-06-22 |
Element Biosciences, Inc. |
Compositions and methods for pairwise sequencing
|
|
US12139727B2
(en)
|
2021-06-18 |
2024-11-12 |
Element Biosciences, Inc. |
Engineered polymerases
|
|
JP2024522795A
(ja)
|
2021-06-18 |
2024-06-21 |
エレメント バイオサイエンシズ,インコーポレイティド |
操作されたポリメラーゼ
|
|
WO2023114392A1
(en)
|
2021-12-16 |
2023-06-22 |
Ultima Genomics, Inc. |
Systems and methods for sequencing with multi-priming
|
|
US12006518B2
(en)
|
2022-02-18 |
2024-06-11 |
Element Biosciences, Inc. |
Engineered polymerases with reduced sequence-specific errors
|
|
EP4551718B1
(en)
|
2022-07-05 |
2026-06-24 |
Element Biosciences, Inc. |
Pcr-free library preparation using double-stranded splint adaptors and methods of use
|
|
AU2023325054A1
(en)
|
2022-08-15 |
2025-02-27 |
Element Biosciences, Inc. |
Methods for preparing nucleic acid nanostructures using compaction oligonucleotides
|
|
CA3264896A1
(en)
|
2022-08-15 |
2024-02-22 |
Element Biosciences, Inc. |
SPATIAL RESOLUTION SURFACE CAPTURE OF NUCLEIC ACIDS
|
|
EP4587566A1
(en)
|
2022-09-12 |
2025-07-23 |
Element Biosciences, Inc. |
Double-stranded splint adaptors with universal long splint strands and methods of use
|
|
KR20260058236A
(ko)
|
2023-07-24 |
2026-04-28 |
엘리먼트 바이오사이언스, 인크. |
고정화된 핵산 콘카테머 분자를 생성하기 위한 지지체상 원형화 및 증폭
|