|
US4458066A
(en)
|
1980-02-29 |
1984-07-03 |
University Patents, Inc. |
Process for preparing polynucleotides
|
|
US4469863A
(en)
|
1980-11-12 |
1984-09-04 |
Ts O Paul O P |
Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof
|
|
US5235033A
(en)
|
1985-03-15 |
1993-08-10 |
Anti-Gene Development Group |
Alpha-morpholino ribonucleoside derivatives and polymers thereof
|
|
US5034506A
(en)
|
1985-03-15 |
1991-07-23 |
Anti-Gene Development Group |
Uncharged morpholino-based polymers having achiral intersubunit linkages
|
|
DE3529478A1
(de)
|
1985-08-16 |
1987-02-19 |
Boehringer Mannheim Gmbh |
7-desaza-2'desoxyguanosin-nukleotide, verfahren zu deren herstellung und deren verwendung zur nukleinsaeure-sequenzierung
|
|
US5216141A
(en)
|
1988-06-06 |
1993-06-01 |
Benner Steven A |
Oligonucleotide analogs containing sulfur linkages
|
|
US5602240A
(en)
|
1990-07-27 |
1997-02-11 |
Ciba Geigy Ag. |
Backbone modified oligonucleotide analogs
|
|
US5386023A
(en)
|
1990-07-27 |
1995-01-31 |
Isis Pharmaceuticals |
Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling
|
|
US5484908A
(en)
|
1991-11-26 |
1996-01-16 |
Gilead Sciences, Inc. |
Oligonucleotides containing 5-propynyl pyrimidines
|
|
TW393513B
(en)
|
1991-11-26 |
2000-06-11 |
Isis Pharmaceuticals Inc |
Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines
|
|
EP0637965B1
(en)
|
1991-11-26 |
2002-10-16 |
Isis Pharmaceuticals, Inc. |
Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines
|
|
US5644048A
(en)
|
1992-01-10 |
1997-07-01 |
Isis Pharmaceuticals, Inc. |
Process for preparing phosphorothioate oligonucleotides
|
|
US5637684A
(en)
|
1994-02-23 |
1997-06-10 |
Isis Pharmaceuticals, Inc. |
Phosphoramidate and phosphorothioamidate oligomeric compounds
|
|
AU3274600A
(en)
|
1999-03-18 |
2000-10-09 |
Exiqon A/S |
One step sample preparation and detection of nucleic acids in complex biologicalsamples
|
|
IL145496A0
(en)
|
1999-03-24 |
2002-06-30 |
Exiqon As |
Improved synthesis of [2.2.1] bicyclo nucleosides
|
|
US6734291B2
(en)
|
1999-03-24 |
2004-05-11 |
Exiqon A/S |
Synthesis of [2.2.1]bicyclo nucleosides
|
|
CN102939291B
(zh)
|
2010-04-14 |
2016-09-07 |
加利福尼亚大学董事会 |
用于病毒感染治疗的具有降低的毒性的膦酸酯
|
|
KR20150130355A
(ko)
|
2013-03-15 |
2015-11-23 |
더 리전트 오브 더 유니버시티 오브 캘리포니아 |
비환식 뉴클레오사이드 포스포네이트 디에스테르
|
|
TW201542581A
(zh)
*
|
2013-09-11 |
2015-11-16 |
艾默理大學 |
核苷酸與核苷治療組成物及其相關用途
|
|
MX377983B
(es)
|
2014-09-15 |
2025-03-04 |
Univ California |
Análogos de nucleótidos.
|
|
TWI698444B
(zh)
|
2014-10-29 |
2020-07-11 |
美商基利科學股份有限公司 |
製備核糖苷的方法
|
|
EP3875462A1
(en)
|
2015-09-15 |
2021-09-08 |
The Regents of The University of California |
Nucleotide analogs
|
|
US10874683B2
(en)
|
2016-03-10 |
2020-12-29 |
Emory University |
N4-hydroxycytidine and derivatives and anti-viral uses related thereto
|
|
WO2019053696A1
(en)
|
2017-09-18 |
2019-03-21 |
Alios Biopharma, Inc. |
SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF
|
|
TWI791193B
(zh)
*
|
2020-02-18 |
2023-02-01 |
美商基利科學股份有限公司 |
抗病毒化合物
|
|
EP4142709A4
(en)
*
|
2020-05-01 |
2024-05-22 |
Irazu Bio |
Method for treating respiratory viral infections comprising administration of fatty acid compositions
|
|
MX2023001002A
(es)
*
|
2020-07-24 |
2023-03-01 |
Univ California |
Farmacos antivirales, composiciones farmaceuticas, y metodos.
|
|
JP7559223B2
(ja)
|
2020-08-24 |
2024-10-01 |
ギリアード サイエンシーズ， インコーポレイテッド |
リン脂質化合物及びその使用
|
|
TWI925033B
(zh)
|
2020-10-16 |
2026-05-11 |
美商基利科學股份有限公司 |
磷脂化合物及其用途
|
|
TW202317144A
(zh)
|
2021-06-14 |
2023-05-01 |
美商維納拓爾斯製藥公司 |
口服生物可利用的核苷類似物
|
|
JP2025508656A
(ja)
|
2022-01-26 |
2025-04-10 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
抗ウイルスプロドラッグ、中期及び長期作用型製剤、並びに方法
|
|
WO2024159117A1
(en)
|
2023-01-26 |
2024-08-02 |
The Regents Of The University Of California |
Antiviral prodrugs, intermediate-and long-acting formulations, and methods
|