JP2025508122A5 - - Google Patents

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Publication number
JP2025508122A5
JP2025508122A5 JP2024553758A JP2024553758A JP2025508122A5 JP 2025508122 A5 JP2025508122 A5 JP 2025508122A5 JP 2024553758 A JP2024553758 A JP 2024553758A JP 2024553758 A JP2024553758 A JP 2024553758A JP 2025508122 A5 JP2025508122 A5 JP 2025508122A5
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JP
Japan
Application number
JP2024553758A
Other languages
Japanese (ja)
Other versions
JPWO2023169226A5 (https=
JP2025508122A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2023/077988 external-priority patent/WO2023169226A1/en
Publication of JP2025508122A publication Critical patent/JP2025508122A/ja
Publication of JPWO2023169226A5 publication Critical patent/JPWO2023169226A5/ja
Publication of JP2025508122A5 publication Critical patent/JP2025508122A5/ja
Pending legal-status Critical Current

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JP2024553758A 2022-03-11 2023-02-23 Parp阻害剤としての置換三環式化合物およびその使用 Pending JP2025508122A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
CN202210260944 2022-03-11
CN202210260944.7 2022-03-11
CN202210448803 2022-04-24
CN202210448803.8 2022-04-24
CN202211219599 2022-09-30
CN202211219599.9 2022-09-30
CN202211505904.0 2022-11-28
CN202211505904 2022-11-28
PCT/CN2023/077988 WO2023169226A1 (en) 2022-03-11 2023-02-23 Substituted tricyclic compounds as parp inhibitors and the use thereof

Publications (3)

Publication Number Publication Date
JP2025508122A JP2025508122A (ja) 2025-03-21
JPWO2023169226A5 JPWO2023169226A5 (https=) 2026-03-04
JP2025508122A5 true JP2025508122A5 (https=) 2026-03-04

Family

ID=87937164

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024553758A Pending JP2025508122A (ja) 2022-03-11 2023-02-23 Parp阻害剤としての置換三環式化合物およびその使用

Country Status (11)

Country Link
US (1) US20250215013A1 (https=)
EP (1) EP4490161A4 (https=)
JP (1) JP2025508122A (https=)
KR (1) KR20240162104A (https=)
CN (1) CN119013279A (https=)
AU (1) AU2023229992A1 (https=)
CA (1) CA3253468A1 (https=)
IL (1) IL315586A (https=)
MX (1) MX2024011086A (https=)
TW (1) TW202400601A (https=)
WO (1) WO2023169226A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2023209820B2 (en) 2022-01-21 2024-10-10 Xinthera, Inc. Parp1 inhibitors and uses thereof
KR20240161147A (ko) 2022-03-14 2024-11-12 슬랩 파마슈티컬스 엘엘씨 다중 사이클릭 화합물
FI4497438T3 (fi) 2022-04-28 2025-10-20 Xinthera Inc Trisyklisiä parp1:n estäjiä ja niiden käyttötapoja
CN119110801A (zh) * 2022-05-07 2024-12-10 南京明德新药研发有限公司 选择性抑制parp1的氟代喹喔啉酮衍生物
JP2025538192A (ja) * 2022-11-10 2025-11-26 上海海和薬物研究開発股▲ふん▼有限公司 縮合三環式parp1阻害剤、その調製方法、および使用
EP4673448A1 (en) * 2023-03-01 2026-01-07 Impact Therapeutics (Shanghai), Inc. Substituted nitrogen-containing tricyclic compounds as parp inhibitors and the use thereof
CN120677162A (zh) * 2023-06-13 2025-09-19 中国医药研究开发中心有限公司 含氮杂环类化合物及其医药用途
TW202525808A (zh) * 2023-09-13 2025-07-01 大陸商上海瑛派藥業有限公司 用作parp1抑制劑的化合物、其用途及包含其之組合物

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPS137402A0 (en) * 2002-03-26 2002-05-09 Fujisawa Pharmaceutical Co., Ltd. Novel tricyclic compounds
CN101528704B (zh) * 2006-09-01 2014-04-09 生华生物科技股份有限公司 丝氨酸-苏氨酸蛋白激酶和parp调节剂
CN101616919B (zh) * 2006-12-28 2012-10-10 雅培制药有限公司 聚(adp核糖)聚合酶抑制剂
KR101779137B1 (ko) * 2009-01-23 2017-09-18 다케다 야쿠힌 고교 가부시키가이샤 폴리(adp-리보스)폴리머라제(parp) 억제제
EP2459561A1 (en) * 2009-07-30 2012-06-06 Takeda Pharmaceutical Company Limited Poly (adp-ribose) polymerase (parp) inhibitors
PH12017502228B1 (en) * 2015-06-09 2022-08-03 Onconic Therapeutics Inc Tricyclic derivative compound, method for preparing same, and pharmaceutical composition comprising same
TW202309025A (zh) * 2021-04-19 2023-03-01 美商辛瑟拉股份有限公司 Parp1抑制劑及其用途
AU2022334408A1 (en) * 2021-08-27 2024-02-15 Impact Therapeutics (Shanghai), Inc. Substituted tricyclic compounds as parp inhibitors and use thereof
JP2025501762A (ja) * 2021-12-22 2025-01-23 シノベーション・セラピューティクス・インコーポレイテッド Parp1阻害剤
WO2023134647A1 (zh) * 2022-01-13 2023-07-20 优领医药科技(香港)有限公司 含哌嗪并环类衍生物、其药学上可接受的盐及其制备方法和应用
FI4497438T3 (fi) * 2022-04-28 2025-10-20 Xinthera Inc Trisyklisiä parp1:n estäjiä ja niiden käyttötapoja
CN119110801A (zh) * 2022-05-07 2024-12-10 南京明德新药研发有限公司 选择性抑制parp1的氟代喹喔啉酮衍生物
CN115232129B (zh) * 2022-08-18 2023-12-01 上海闻耐医药科技有限公司 一种parp1选择性抑制剂及其制备方法和用途
JP2025538192A (ja) * 2022-11-10 2025-11-26 上海海和薬物研究開発股▲ふん▼有限公司 縮合三環式parp1阻害剤、その調製方法、および使用

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