JP2025508046A - 核酸センサーに関連する組成物及び方法 - Google Patents
核酸センサーに関連する組成物及び方法 Download PDFInfo
- Publication number
- JP2025508046A JP2025508046A JP2024553342A JP2024553342A JP2025508046A JP 2025508046 A JP2025508046 A JP 2025508046A JP 2024553342 A JP2024553342 A JP 2024553342A JP 2024553342 A JP2024553342 A JP 2024553342A JP 2025508046 A JP2025508046 A JP 2025508046A
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- sensor
- domain
- toehold
- double
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6825—Nucleic acid detection involving sensors
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263317424P | 2022-03-07 | 2022-03-07 | |
| US63/317,424 | 2022-03-07 | ||
| PCT/US2023/063860 WO2023172911A2 (en) | 2022-03-07 | 2023-03-07 | Compositions and methods related to nucleic acid sensors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025508046A true JP2025508046A (ja) | 2025-03-21 |
| JP2025508046A5 JP2025508046A5 (enExample) | 2026-03-13 |
Family
ID=87935960
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024553342A Pending JP2025508046A (ja) | 2022-03-07 | 2023-03-07 | 核酸センサーに関連する組成物及び方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20250188517A1 (enExample) |
| EP (1) | EP4490310A4 (enExample) |
| JP (1) | JP2025508046A (enExample) |
| CN (1) | CN119110852A (enExample) |
| CA (1) | CA3245380A1 (enExample) |
| WO (1) | WO2023172911A2 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2026064708A1 (en) * | 2024-09-20 | 2026-03-26 | Arizona Board Of Regents On Behalf Of Arizona State University | Compositions and methods related to nucleic acid nanopores |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017112941A1 (en) * | 2015-12-23 | 2017-06-29 | The Regents Of The University Of California | Nano-sensors for nucleic acid detection and discrimination |
| US11674141B2 (en) * | 2018-02-28 | 2023-06-13 | National University Corporation Tokyo Medical And Dental University | Ischemic-lesion-site-specific gene therapy |
| US20230212681A1 (en) * | 2020-02-17 | 2023-07-06 | Arizona Board Of Regents On Behalf Of Arizona State University | Transmembrane nanosensor arrays for rapid, ultra-sensitive and specific digital quantification of internal micro-rna content of intact exosomes |
| WO2022081766A1 (en) * | 2020-10-13 | 2022-04-21 | Arizona Board Of Regents On Behalf Of Arizona State University | Transmembrane sensors and molecular amplifiers for lysis-free detection of intracellular targets |
-
2023
- 2023-03-07 CA CA3245380A patent/CA3245380A1/en active Pending
- 2023-03-07 WO PCT/US2023/063860 patent/WO2023172911A2/en not_active Ceased
- 2023-03-07 US US18/844,872 patent/US20250188517A1/en active Pending
- 2023-03-07 JP JP2024553342A patent/JP2025508046A/ja active Pending
- 2023-03-07 CN CN202380026045.3A patent/CN119110852A/zh active Pending
- 2023-03-07 EP EP23767616.8A patent/EP4490310A4/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA3245380A1 (en) | 2023-09-14 |
| EP4490310A4 (en) | 2026-04-08 |
| WO2023172911A2 (en) | 2023-09-14 |
| WO2023172911A3 (en) | 2023-10-26 |
| CN119110852A (zh) | 2024-12-10 |
| US20250188517A1 (en) | 2025-06-12 |
| EP4490310A2 (en) | 2025-01-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20240052400A1 (en) | Unimolecular aptamer-based sensors for pathogen detection | |
| JP7477183B2 (ja) | 新規な等温単一反応用プローブセット及びその用途 | |
| US20090130650A1 (en) | Methods for the production of highly sensitive and specific cell surface probes | |
| JPH09504950A (ja) | 核酸検出用ハイブリダイゼーションプローブ、共通ステム、方法およびキット | |
| US20060014191A1 (en) | Analog probe complexes | |
| Morris et al. | Single-molecule kinetic investigation of cocaine-dependent split-aptamer assembly | |
| US8703734B2 (en) | Nanoprobes for detection or modification of molecules | |
| US20200370100A1 (en) | Fluorescent nucleic acid nanostructure-graphene biosensor for nucleic acid detection | |
| JP2020503030A (ja) | 2パートメディエータプローブ | |
| JP2002526032A (ja) | Rna結合化合物の発見のための方法およびキット | |
| BR112021013787A2 (pt) | Composições reagentes marcadas com alta densidade e métodos para sequenciamento | |
| Astakhova et al. | Perylene attached to 2′-amino-LNA: synthesis, incorporation into oligonucleotides, and remarkable fluorescence properties in vitro and in cell culture | |
| US20220195497A1 (en) | HYBRIDIZING all-LNA OLIGONUCLEOTIDES | |
| Napoletano et al. | MicroLOCK: Highly stable microgel biosensor using locked nucleic acids as bioreceptors for sensitive and selective detection of let-7a | |
| US20030073091A1 (en) | Use of generic oligonucleotide microchips to detect protein-nucleic acid interactions | |
| WO2006065597A2 (en) | Id-tag complexes, arrays, and methods of use thereof | |
| Bruno et al. | Competitive FRET-aptamer-based detection of methylphosphonic acid, a common nerve agent metabolite | |
| US20250188517A1 (en) | Compositions and methods related to nucleic acid sensors | |
| US20090239762A1 (en) | Aptamers that bind abnormal cells | |
| Lilley | Analysis of global conformational transitions in ribozymes | |
| US20160152656A1 (en) | Methods of Using Phosphoramidation Reaction for Conjugation-Labeling Nucleic Acids | |
| US20230175040A1 (en) | Epiprinter Technology and Methods of Use for Detecting Biomolecules | |
| Chu et al. | A G-quadruplex DNAzyme chemiluminescence aptasensor based on the target triggered DNA recycling for sensitive detection of adenosine | |
| Zatsepin et al. | 2'‐Functionalized Nucleic Acids as Structural Tools in Molecular Biology | |
| JPH0275958A (ja) | Dna検出法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20260305 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20260305 |