CN119110852A - 与核酸传感器相关的组合物和方法 - Google Patents

与核酸传感器相关的组合物和方法 Download PDF

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Publication number
CN119110852A
CN119110852A CN202380026045.3A CN202380026045A CN119110852A CN 119110852 A CN119110852 A CN 119110852A CN 202380026045 A CN202380026045 A CN 202380026045A CN 119110852 A CN119110852 A CN 119110852A
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CN
China
Prior art keywords
sensor
nucleic acid
domain
hairpin
hydrophobic
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Pending
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CN202380026045.3A
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English (en)
Chinese (zh)
Inventor
R·F·哈里亚迪
G·B·M·威斯纳
R·萨斯马尔
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Arizona State University Downtown Phoenix campus
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Arizona State University Downtown Phoenix campus
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Application filed by Arizona State University Downtown Phoenix campus filed Critical Arizona State University Downtown Phoenix campus
Publication of CN119110852A publication Critical patent/CN119110852A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN202380026045.3A 2022-03-07 2023-03-07 与核酸传感器相关的组合物和方法 Pending CN119110852A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263317424P 2022-03-07 2022-03-07
US63/317,424 2022-03-07
PCT/US2023/063860 WO2023172911A2 (en) 2022-03-07 2023-03-07 Compositions and methods related to nucleic acid sensors

Publications (1)

Publication Number Publication Date
CN119110852A true CN119110852A (zh) 2024-12-10

Family

ID=87935960

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202380026045.3A Pending CN119110852A (zh) 2022-03-07 2023-03-07 与核酸传感器相关的组合物和方法

Country Status (6)

Country Link
US (1) US20250188517A1 (enExample)
EP (1) EP4490310A4 (enExample)
JP (1) JP2025508046A (enExample)
CN (1) CN119110852A (enExample)
CA (1) CA3245380A1 (enExample)
WO (1) WO2023172911A2 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026064708A1 (en) * 2024-09-20 2026-03-26 Arizona Board Of Regents On Behalf Of Arizona State University Compositions and methods related to nucleic acid nanopores

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017112941A1 (en) * 2015-12-23 2017-06-29 The Regents Of The University Of California Nano-sensors for nucleic acid detection and discrimination
US11674141B2 (en) * 2018-02-28 2023-06-13 National University Corporation Tokyo Medical And Dental University Ischemic-lesion-site-specific gene therapy
US20230212681A1 (en) * 2020-02-17 2023-07-06 Arizona Board Of Regents On Behalf Of Arizona State University Transmembrane nanosensor arrays for rapid, ultra-sensitive and specific digital quantification of internal micro-rna content of intact exosomes
WO2022081766A1 (en) * 2020-10-13 2022-04-21 Arizona Board Of Regents On Behalf Of Arizona State University Transmembrane sensors and molecular amplifiers for lysis-free detection of intracellular targets

Also Published As

Publication number Publication date
CA3245380A1 (en) 2023-09-14
EP4490310A4 (en) 2026-04-08
JP2025508046A (ja) 2025-03-21
WO2023172911A2 (en) 2023-09-14
WO2023172911A3 (en) 2023-10-26
US20250188517A1 (en) 2025-06-12
EP4490310A2 (en) 2025-01-15

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