JP2025507571A5 - - Google Patents

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Publication number
JP2025507571A5
JP2025507571A5 JP2024548426A JP2024548426A JP2025507571A5 JP 2025507571 A5 JP2025507571 A5 JP 2025507571A5 JP 2024548426 A JP2024548426 A JP 2024548426A JP 2024548426 A JP2024548426 A JP 2024548426A JP 2025507571 A5 JP2025507571 A5 JP 2025507571A5
Authority
JP
Japan
Prior art keywords
composition
pharmaceutical composition
lnp
cancer
antigenic peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024548426A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025507571A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/062844 external-priority patent/WO2023159197A1/en
Publication of JP2025507571A publication Critical patent/JP2025507571A/ja
Publication of JP2025507571A5 publication Critical patent/JP2025507571A5/ja
Pending legal-status Critical Current

Links

JP2024548426A 2022-02-18 2023-02-17 チェックポイントがんワクチンをコードするmRNA及びその使用 Pending JP2025507571A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202263311716P 2022-02-18 2022-02-18
US63/311,716 2022-02-18
US202263381460P 2022-10-28 2022-10-28
US63/381,460 2022-10-28
PCT/US2023/062844 WO2023159197A1 (en) 2022-02-18 2023-02-17 Mrnas encoding checkpoint cancer vaccines and uses thereof

Publications (2)

Publication Number Publication Date
JP2025507571A JP2025507571A (ja) 2025-03-21
JP2025507571A5 true JP2025507571A5 (enExample) 2026-02-26

Family

ID=85703979

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024548426A Pending JP2025507571A (ja) 2022-02-18 2023-02-17 チェックポイントがんワクチンをコードするmRNA及びその使用

Country Status (5)

Country Link
US (1) US20250213664A1 (enExample)
EP (1) EP4479085A1 (enExample)
JP (1) JP2025507571A (enExample)
TW (1) TW202345864A (enExample)
WO (1) WO2023159197A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026008026A1 (en) * 2024-07-03 2026-01-08 Everest Medicines (China) Co., Ltd. Pd-l1 cancer vaccines and uses thereof
WO2026008017A1 (en) * 2024-07-03 2026-01-08 Everest Medicines (China) Co., Ltd. Cancer vaccines and uses thereof

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050222064A1 (en) 2002-02-20 2005-10-06 Sirna Therapeutics, Inc. Polycationic compositions for cellular delivery of polynucleotides
US7404969B2 (en) 2005-02-14 2008-07-29 Sirna Therapeutics, Inc. Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
DE102005046490A1 (de) 2005-09-28 2007-03-29 Johannes-Gutenberg-Universität Mainz Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen
DK2205618T3 (en) 2007-09-26 2017-02-20 Intrexon Corp SYNTHETIC 5 'NON-TRANSLATED REGIONS, EXPRESSION VECTORS AND PROCEDURES FOR INCREASING TRANSGENIC EXPRESSION
JP5539962B2 (ja) 2008-04-25 2014-07-02 ノースウェスタン、ユニバーシティ コレステロールを隔離するのに適したナノ構造体
PL215513B1 (pl) 2008-06-06 2013-12-31 Univ Warszawski Nowe boranofosforanowe analogi dinukleotydów, ich zastosowanie, czasteczka RNA, sposób otrzymywania RNA oraz sposób otrzymywania peptydów lub bialka
KR20220038506A (ko) 2009-06-10 2022-03-28 알닐람 파마슈티칼스 인코포레이티드 향상된 지질 조성물
US9999673B2 (en) 2011-01-11 2018-06-19 Alnylam Pharmaceuticals, Inc. PEGylated lipids and their use for drug delivery
CA2831613A1 (en) 2011-03-31 2012-10-04 Moderna Therapeutics, Inc. Delivery and formulation of engineered nucleic acids
EP4074693A1 (en) 2011-06-08 2022-10-19 Translate Bio, Inc. Cleavable lipids
WO2013039857A1 (en) 2011-09-12 2013-03-21 modeRNA Therapeutics Engineered nucleic acids and methods of use thereof
PT3682905T (pt) 2011-10-03 2022-04-07 Modernatx Inc Nucleósidos, nucleótidos e ácidos nucleicos modificados e respetivas utilizações
DE21212055T1 (de) 2011-12-07 2022-08-04 Alnylam Pharmaceuticals, Inc. Biologisch abbaubare lipide zur freisetzung von wirkstoffen
WO2013116126A1 (en) 2012-02-01 2013-08-08 Merck Sharp & Dohme Corp. Novel low molecular weight, biodegradable cationic lipids for oligonucleotide delivery
WO2013151664A1 (en) 2012-04-02 2013-10-10 modeRNA Therapeutics Modified polynucleotides for the production of proteins
WO2014093924A1 (en) 2012-12-13 2014-06-19 Moderna Therapeutics, Inc. Modified nucleic acid molecules and uses thereof
WO2014164253A1 (en) 2013-03-09 2014-10-09 Moderna Therapeutics, Inc. Heterologous untranslated regions for mrna
WO2015130584A2 (en) 2014-02-25 2015-09-03 Merck Sharp & Dohme Corp. Lipid nanoparticle vaccine adjuvants and antigen delivery systems
CA2953341C (en) 2014-06-25 2023-01-24 Acuitas Therapeutics Inc. Lipids and lipid nanoparticle formulations for delivery of nucleic acids
HRP20220156T1 (hr) * 2015-09-17 2022-04-15 Modernatx, Inc. Spojevi i pripravci za unutarstaničnu isporuku terapeutskih sredstava
US11866754B2 (en) 2015-10-16 2024-01-09 Modernatx, Inc. Trinucleotide mRNA cap analogs
CN108368028B (zh) 2015-10-28 2021-09-03 爱康泰生治疗公司 用于递送核酸的新型脂质和脂质纳米颗粒制剂
HUE064857T2 (hu) * 2016-03-04 2024-04-28 Io Biotech Aps Kombinációs terápia a rák ellen
RS63625B1 (sr) 2016-05-18 2022-10-31 Modernatx Inc Kombinacije irnk koje kodiraju imunomodulirajuće polipeptide i njihova upotreba
CA3042015A1 (en) * 2016-10-26 2018-05-03 Modernatx, Inc. Messenger ribonucleic acids for enhancing immune responses and methods of use thereof

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