JP2025507571A5 - - Google Patents
Info
- Publication number
- JP2025507571A5 JP2025507571A5 JP2024548426A JP2024548426A JP2025507571A5 JP 2025507571 A5 JP2025507571 A5 JP 2025507571A5 JP 2024548426 A JP2024548426 A JP 2024548426A JP 2024548426 A JP2024548426 A JP 2024548426A JP 2025507571 A5 JP2025507571 A5 JP 2025507571A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- pharmaceutical composition
- lnp
- cancer
- antigenic peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263311716P | 2022-02-18 | 2022-02-18 | |
| US63/311,716 | 2022-02-18 | ||
| US202263381460P | 2022-10-28 | 2022-10-28 | |
| US63/381,460 | 2022-10-28 | ||
| PCT/US2023/062844 WO2023159197A1 (en) | 2022-02-18 | 2023-02-17 | Mrnas encoding checkpoint cancer vaccines and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025507571A JP2025507571A (ja) | 2025-03-21 |
| JP2025507571A5 true JP2025507571A5 (enExample) | 2026-02-26 |
Family
ID=85703979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024548426A Pending JP2025507571A (ja) | 2022-02-18 | 2023-02-17 | チェックポイントがんワクチンをコードするmRNA及びその使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20250213664A1 (enExample) |
| EP (1) | EP4479085A1 (enExample) |
| JP (1) | JP2025507571A (enExample) |
| TW (1) | TW202345864A (enExample) |
| WO (1) | WO2023159197A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2026008026A1 (en) * | 2024-07-03 | 2026-01-08 | Everest Medicines (China) Co., Ltd. | Pd-l1 cancer vaccines and uses thereof |
| WO2026008017A1 (en) * | 2024-07-03 | 2026-01-08 | Everest Medicines (China) Co., Ltd. | Cancer vaccines and uses thereof |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050222064A1 (en) | 2002-02-20 | 2005-10-06 | Sirna Therapeutics, Inc. | Polycationic compositions for cellular delivery of polynucleotides |
| US7404969B2 (en) | 2005-02-14 | 2008-07-29 | Sirna Therapeutics, Inc. | Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules |
| DE102005046490A1 (de) | 2005-09-28 | 2007-03-29 | Johannes-Gutenberg-Universität Mainz | Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen |
| DK2205618T3 (en) | 2007-09-26 | 2017-02-20 | Intrexon Corp | SYNTHETIC 5 'NON-TRANSLATED REGIONS, EXPRESSION VECTORS AND PROCEDURES FOR INCREASING TRANSGENIC EXPRESSION |
| JP5539962B2 (ja) | 2008-04-25 | 2014-07-02 | ノースウェスタン、ユニバーシティ | コレステロールを隔離するのに適したナノ構造体 |
| PL215513B1 (pl) | 2008-06-06 | 2013-12-31 | Univ Warszawski | Nowe boranofosforanowe analogi dinukleotydów, ich zastosowanie, czasteczka RNA, sposób otrzymywania RNA oraz sposób otrzymywania peptydów lub bialka |
| KR20220038506A (ko) | 2009-06-10 | 2022-03-28 | 알닐람 파마슈티칼스 인코포레이티드 | 향상된 지질 조성물 |
| US9999673B2 (en) | 2011-01-11 | 2018-06-19 | Alnylam Pharmaceuticals, Inc. | PEGylated lipids and their use for drug delivery |
| CA2831613A1 (en) | 2011-03-31 | 2012-10-04 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
| EP4074693A1 (en) | 2011-06-08 | 2022-10-19 | Translate Bio, Inc. | Cleavable lipids |
| WO2013039857A1 (en) | 2011-09-12 | 2013-03-21 | modeRNA Therapeutics | Engineered nucleic acids and methods of use thereof |
| PT3682905T (pt) | 2011-10-03 | 2022-04-07 | Modernatx Inc | Nucleósidos, nucleótidos e ácidos nucleicos modificados e respetivas utilizações |
| DE21212055T1 (de) | 2011-12-07 | 2022-08-04 | Alnylam Pharmaceuticals, Inc. | Biologisch abbaubare lipide zur freisetzung von wirkstoffen |
| WO2013116126A1 (en) | 2012-02-01 | 2013-08-08 | Merck Sharp & Dohme Corp. | Novel low molecular weight, biodegradable cationic lipids for oligonucleotide delivery |
| WO2013151664A1 (en) | 2012-04-02 | 2013-10-10 | modeRNA Therapeutics | Modified polynucleotides for the production of proteins |
| WO2014093924A1 (en) | 2012-12-13 | 2014-06-19 | Moderna Therapeutics, Inc. | Modified nucleic acid molecules and uses thereof |
| WO2014164253A1 (en) | 2013-03-09 | 2014-10-09 | Moderna Therapeutics, Inc. | Heterologous untranslated regions for mrna |
| WO2015130584A2 (en) | 2014-02-25 | 2015-09-03 | Merck Sharp & Dohme Corp. | Lipid nanoparticle vaccine adjuvants and antigen delivery systems |
| CA2953341C (en) | 2014-06-25 | 2023-01-24 | Acuitas Therapeutics Inc. | Lipids and lipid nanoparticle formulations for delivery of nucleic acids |
| HRP20220156T1 (hr) * | 2015-09-17 | 2022-04-15 | Modernatx, Inc. | Spojevi i pripravci za unutarstaničnu isporuku terapeutskih sredstava |
| US11866754B2 (en) | 2015-10-16 | 2024-01-09 | Modernatx, Inc. | Trinucleotide mRNA cap analogs |
| CN108368028B (zh) | 2015-10-28 | 2021-09-03 | 爱康泰生治疗公司 | 用于递送核酸的新型脂质和脂质纳米颗粒制剂 |
| HUE064857T2 (hu) * | 2016-03-04 | 2024-04-28 | Io Biotech Aps | Kombinációs terápia a rák ellen |
| RS63625B1 (sr) | 2016-05-18 | 2022-10-31 | Modernatx Inc | Kombinacije irnk koje kodiraju imunomodulirajuće polipeptide i njihova upotreba |
| CA3042015A1 (en) * | 2016-10-26 | 2018-05-03 | Modernatx, Inc. | Messenger ribonucleic acids for enhancing immune responses and methods of use thereof |
-
2023
- 2023-02-17 EP EP23711903.7A patent/EP4479085A1/en active Pending
- 2023-02-17 US US18/839,326 patent/US20250213664A1/en active Pending
- 2023-02-17 JP JP2024548426A patent/JP2025507571A/ja active Pending
- 2023-02-17 TW TW112105879A patent/TW202345864A/zh unknown
- 2023-02-17 WO PCT/US2023/062844 patent/WO2023159197A1/en not_active Ceased
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