JP2025505434A5 - - Google Patents

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Publication number
JP2025505434A5
JP2025505434A5 JP2024545121A JP2024545121A JP2025505434A5 JP 2025505434 A5 JP2025505434 A5 JP 2025505434A5 JP 2024545121 A JP2024545121 A JP 2024545121A JP 2024545121 A JP2024545121 A JP 2024545121A JP 2025505434 A5 JP2025505434 A5 JP 2025505434A5
Authority
JP
Japan
Prior art keywords
protein
cancer
drugs
optionally
prodrug construct
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024545121A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025505434A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2023/052280 external-priority patent/WO2023144412A1/en
Publication of JP2025505434A publication Critical patent/JP2025505434A/ja
Publication of JP2025505434A5 publication Critical patent/JP2025505434A5/ja
Pending legal-status Critical Current

Links

JP2024545121A 2022-01-31 2023-01-31 タンパク質構造変化に基づくバイオ医薬プロドラッグプラットホーム Pending JP2025505434A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP22154258 2022-01-31
EP22154258.2 2022-01-31
PCT/EP2023/052280 WO2023144412A1 (en) 2022-01-31 2023-01-31 A biopharmaceutical prodrug platform based on protein conformational change

Publications (2)

Publication Number Publication Date
JP2025505434A JP2025505434A (ja) 2025-02-26
JP2025505434A5 true JP2025505434A5 (https=) 2026-01-29

Family

ID=80118874

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024545121A Pending JP2025505434A (ja) 2022-01-31 2023-01-31 タンパク質構造変化に基づくバイオ医薬プロドラッグプラットホーム

Country Status (7)

Country Link
US (1) US20240374745A1 (https=)
EP (1) EP4473007A1 (https=)
JP (1) JP2025505434A (https=)
CN (1) CN118613501A (https=)
AU (1) AU2023211165A1 (https=)
CA (1) CA3243392A1 (https=)
WO (1) WO2023144412A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024261212A1 (en) * 2023-06-22 2024-12-26 Aarhus Universitet Multi-specific proteinaceous prodrug constructs
WO2025128434A1 (en) * 2023-12-14 2025-06-19 The Regents Of The University Of Colorado, A Body Corporate Compositions and methods for the treatment of ven/aza resistant acute myeloid leukemia

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2324864A1 (en) * 1998-04-01 1999-10-07 Duke University Immune response modulator alpha-2 macroglobulin complex
SG175602A1 (en) * 2006-07-05 2011-11-28 Catalyst Biosciences Inc Protease screening methods and proteases identified thereby
JP6861152B2 (ja) * 2014-11-20 2021-04-21 サイトニックス コーポレイション 治療用変異体アルファ2−マクログロブリン組成物
EP3762406A2 (en) * 2018-03-09 2021-01-13 Askgene Pharma, Inc. Cytokine prodrugs
AU2019271148B9 (en) * 2018-05-14 2025-05-29 Werewolf Therapeutics, Inc. Activatable interleukin-2 polypeptides and methods of use thereof
WO2019222282A1 (en) * 2018-05-14 2019-11-21 Harpoon Therapeutics, Inc. Conditionally activated binding protein comprising a sterically occluded target binding domain

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