JP2025504795A5 - - Google Patents

Info

Publication number
JP2025504795A5
JP2025504795A5 JP2024541191A JP2024541191A JP2025504795A5 JP 2025504795 A5 JP2025504795 A5 JP 2025504795A5 JP 2024541191 A JP2024541191 A JP 2024541191A JP 2024541191 A JP2024541191 A JP 2024541191A JP 2025504795 A5 JP2025504795 A5 JP 2025504795A5
Authority
JP
Japan
Prior art keywords
amino acid
acid sequence
seq
bispecific antibody
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024541191A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025504795A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2023/071314 external-priority patent/WO2023131328A1/zh
Publication of JP2025504795A publication Critical patent/JP2025504795A/ja
Publication of JP2025504795A5 publication Critical patent/JP2025504795A5/ja
Pending legal-status Critical Current

Links

JP2024541191A 2022-01-10 2023-01-09 抗体及びその用途 Pending JP2025504795A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
CNPCT/CN2022/071080 2022-01-10
CN2022071080 2022-01-10
CN202210352672 2022-04-01
CN202210352672.3 2022-04-01
CN202310005123.3 2023-01-03
CN202310005123 2023-01-03
PCT/CN2023/071314 WO2023131328A1 (zh) 2022-01-10 2023-01-09 一种抗体及其用途

Publications (2)

Publication Number Publication Date
JP2025504795A JP2025504795A (ja) 2025-02-19
JP2025504795A5 true JP2025504795A5 (https=) 2026-01-20

Family

ID=87073288

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024541191A Pending JP2025504795A (ja) 2022-01-10 2023-01-09 抗体及びその用途

Country Status (6)

Country Link
US (1) US20250092135A1 (https=)
EP (1) EP4464722A4 (https=)
JP (1) JP2025504795A (https=)
CN (1) CN118510810A (https=)
TW (1) TW202334234A (https=)
WO (1) WO2023131328A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117024596B (zh) * 2023-08-18 2024-02-27 镜像绮点(上海)细胞技术有限公司 肿瘤原代细胞特异性标记与活体成像
CN120005019A (zh) * 2023-11-14 2025-05-16 成都优赛诺生物科技有限公司 一种靶向gprc5d的单域抗体、嵌合抗原受体及其应用
WO2025194478A1 (en) * 2024-03-22 2025-09-25 Biofront Ltd Antibodies binding to cd3 and gprc5d, and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004035537A2 (en) 2002-10-16 2004-04-29 Euro-Celtique S.A. Antibodies that bind cell-associated ca 125/o772p and methods of use thereof
JP2016538275A (ja) * 2013-11-04 2016-12-08 グレンマーク ファーマシューティカルズ, エセ.アー. T細胞再標的化ヘテロ二量体免疫グロブリン(hetero−dimeric immunoglobulin)の製造
EP3177643B1 (en) 2014-08-04 2019-05-08 F.Hoffmann-La Roche Ag Bispecific t cell activating antigen binding molecules
BR112017011932A8 (pt) * 2014-12-05 2022-11-08 Memorial Sloan Kettering Cancer Center Anticorpos direcionados a receptor acoplado a proteína g e métodos de uso
TWI781108B (zh) * 2016-07-20 2022-10-21 比利時商健生藥品公司 抗gprc5d抗體、結合gprc5d與cd3之雙特異性抗原結合分子及其用途
JP7066690B2 (ja) * 2016-09-23 2022-05-13 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 抗muc16(ムチン16)抗体
TW202504917A (zh) 2018-06-21 2025-02-01 美商再生元醫藥公司 用雙特異性抗CD3xMUC16抗體及抗PD-1抗體治療癌症之方法
CN114174338A (zh) * 2019-07-31 2022-03-11 豪夫迈·罗氏有限公司 与gprc5d结合的抗体

Similar Documents

Publication Publication Date Title
Zhang et al. The development of bispecific antibodies and their applications in tumor immune escape
ES2801873T3 (es) Anticuerpo de PDL-1, composición farmacéutica del mismo y sus usos
Kontermann et al. Bispecific antibodies
AU2004242847B2 (en) Pharmaceutical composition comprising a bispecific antibody for EpCAM
JP2025504795A5 (https=)
JP2022516557A5 (https=)
Xiong et al. Efficient inhibition of human B-cell lymphoma xenografts with an anti-CD20× anti-CD3 bispecific diabody
TW201040265A (en) Multispecific antibodies comprising full length antibodies and single chain Fab fragments
Müller et al. Bispecific Antibodies
JP2023159379A (ja) Pd-1とvegfを標的とした四価二重特異性抗体、その製造方法および用途
WO2023051727A1 (zh) 结合cd3的抗体及其用途
JP2025508066A (ja) 目的としたt細胞活性化のためのcd28二重特異性抗体
CN106831996A (zh) 新型双特异性抗体及其用途
CN113490690A (zh) 异源二聚体融合蛋白
Acheampong Bispecific antibody (bsAb) construct formats and their application in cancer therapy
JP2022521305A (ja) 抗pd-l1抗体及びその使用
JP2025511288A (ja) 抗pvrig抗体、その医薬組成物及びその使用
WO2018237341A1 (en) A TARGET CELL-DEPENDENT T CELL ENGAGING AND ACTIVATION ASYMMETRIC HETERODIMERIC Fc-ScFv FUSION ANTIBODY FORMAT FOR CANCER THERAPY
JP2024521701A (ja) 抗cd137抗体及びその使用方法
CN113004416B (zh) 靶向her2-cd137双特异性抗体的构建及其应用
Ko et al. Engineering antibodies for dual specificity and enhanced potency
CN120344558A (zh) 双特异性/多特异性抗体及其用途
EP4682172A1 (en) Anti-muc17, anti-cd3 and anti-cd28 trispecific antibody
WO2025201240A1 (en) Antibodies targeting cd3, cd28, and pd-l1 and uses thereof
Vega et al. New antibody formats