JP2025504384A5 - - Google Patents

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Publication number
JP2025504384A5
JP2025504384A5 JP2024541017A JP2024541017A JP2025504384A5 JP 2025504384 A5 JP2025504384 A5 JP 2025504384A5 JP 2024541017 A JP2024541017 A JP 2024541017A JP 2024541017 A JP2024541017 A JP 2024541017A JP 2025504384 A5 JP2025504384 A5 JP 2025504384A5
Authority
JP
Japan
Prior art keywords
computing system
sequence variants
biomolecular sequence
training
biomolecular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024541017A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025504384A (ja
Filing date
Publication date
Priority claimed from US18/046,849 external-priority patent/US20230268026A1/en
Application filed filed Critical
Publication of JP2025504384A publication Critical patent/JP2025504384A/ja
Publication of JP2025504384A5 publication Critical patent/JP2025504384A5/ja
Pending legal-status Critical Current

Links

JP2024541017A 2022-01-07 2023-01-05 事前に特定された属性を伴う生体分子配列バリアントの設計 Pending JP2025504384A (ja)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US202263297679P 2022-01-07 2022-01-07
US63/297,679 2022-01-07
US202263320067P 2022-03-15 2022-03-15
US63/320,067 2022-03-15
US202263338433P 2022-05-04 2022-05-04
US202263338398P 2022-05-04 2022-05-04
US63/338,433 2022-05-04
US63/338,398 2022-05-04
US202263339450P 2022-05-07 2022-05-07
US63/339,450 2022-05-07
US202263398222P 2022-08-15 2022-08-15
US63/398,222 2022-08-15
US18/046,849 US20230268026A1 (en) 2022-01-07 2022-10-14 Designing biomolecule sequence variants with pre-specified attributes
US18/046,849 2022-10-14
PCT/US2023/060167 WO2023133462A1 (en) 2022-01-07 2023-01-05 Designing biomolecule sequence variants with pre-specified attributes

Publications (2)

Publication Number Publication Date
JP2025504384A JP2025504384A (ja) 2025-02-12
JP2025504384A5 true JP2025504384A5 (https=) 2026-01-14

Family

ID=85227256

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024541017A Pending JP2025504384A (ja) 2022-01-07 2023-01-05 事前に特定された属性を伴う生体分子配列バリアントの設計

Country Status (9)

Country Link
US (1) US20230268026A1 (https=)
EP (1) EP4460827A1 (https=)
JP (1) JP2025504384A (https=)
KR (1) KR20240141868A (https=)
AU (1) AU2023204806A1 (https=)
CA (1) CA3247366A1 (https=)
IL (1) IL313957A (https=)
MX (1) MX2024008515A (https=)
WO (1) WO2023133462A1 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12282941B2 (en) * 2022-06-30 2025-04-22 Constant Contact, Inc. Email subject line generation method
CN115747089A (zh) * 2022-07-06 2023-03-07 河南省巴饲福微生物技术研究院 一种生产谷胱甘肽的重组酿酒酵母菌及其构建方法
US20240047006A1 (en) * 2022-07-07 2024-02-08 Lurong Pan Artificial intelligence system and method for designing protein sequences
WO2025058962A1 (en) * 2023-09-11 2025-03-20 Absci Corporation High-throughput methods for kinetic characterization, quantifying and optimizing antibodies and antibody fragments expression in bacteria
CN117079716B (zh) * 2023-09-13 2024-04-05 江苏运动健康研究院 一种基于基因检测的肿瘤用药方案的深度学习预测方法
CN116994654B (zh) * 2023-09-27 2023-12-29 北京立康生命科技有限公司 一种用于鉴定与mhc-i/hla-i类结合及tcr识别肽段的方法、设备及存储介质
US20250109209A1 (en) 2023-10-03 2025-04-03 Absci Corporation Tl1a associated antibody compositions and methods of use
WO2025122885A1 (en) 2023-12-08 2025-06-12 Absci Corporation Anti-her2 associated antibody compositions designed by artificial intelligence and methods of use
WO2025144700A1 (en) 2023-12-27 2025-07-03 Absci Corporation Nanobody library screening using bacterial surface display
WO2025155628A1 (en) * 2024-01-16 2025-07-24 The Regents Of The University Of California Interpretable deep learning predicts chemoresistance
WO2025170869A1 (en) * 2024-02-06 2025-08-14 Aikium Inc. Multi-objective designed molecules and generation thereof
US20250279158A1 (en) * 2024-02-29 2025-09-04 Lurong Pan Computer-assisted method and system for evaluating and modifying immunogenicity of protein sequences using a protein large language model
WO2025255259A1 (en) * 2024-06-06 2025-12-11 Generate Biomedicines, Inc. Machine learning-guided generation of cross-reactive neutralizing antigen binding molecules against viral proteins
WO2026019845A1 (en) * 2024-07-16 2026-01-22 Hepta Bio, Inc. Generalizable transformer for disease state classification from liquid biopsies

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8178338B2 (en) 2005-07-01 2012-05-15 The Regents Of The University Of California Inducible expression vectors and methods of use thereof
CN107119095B (zh) 2008-01-03 2022-07-05 康乃尔研究基金会有限公司 原核生物中的糖基化蛋白表达
WO2017106583A1 (en) 2015-12-15 2017-06-22 Absci, Llc Cytoplasmic expression system
US20150353940A1 (en) 2013-08-05 2015-12-10 Absci, Llc Vectors for use in an inducible coexpression system
EP3924971A1 (en) 2019-02-11 2021-12-22 Flagship Pioneering Innovations VI, LLC Machine learning guided polypeptide analysis
WO2020208555A1 (en) * 2019-04-09 2020-10-15 Eth Zurich Systems and methods to classify antibodies
EP4008006A1 (en) 2019-08-02 2022-06-08 Flagship Pioneering Innovations VI, LLC Machine learning guided polypeptide design
MX2022008801A (es) 2020-01-15 2022-11-07 Absci Corp Enriquecimiento de células específico de la actividad.
JP2023513578A (ja) 2020-02-11 2023-03-31 アブサイ コーポレーション 近接アッセイ

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