MX2024008515A - Diseño de variantes de secuencia de biomolécula con atributos especificados previamente. - Google Patents
Diseño de variantes de secuencia de biomolécula con atributos especificados previamente.Info
- Publication number
- MX2024008515A MX2024008515A MX2024008515A MX2024008515A MX2024008515A MX 2024008515 A MX2024008515 A MX 2024008515A MX 2024008515 A MX2024008515 A MX 2024008515A MX 2024008515 A MX2024008515 A MX 2024008515A MX 2024008515 A MX2024008515 A MX 2024008515A
- Authority
- MX
- Mexico
- Prior art keywords
- biomolecule sequence
- sequence variants
- computing system
- biomolecule
- interest
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/30—Detection of binding sites or motifs
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
- G06N3/00—Computing arrangements based on biological models
- G06N3/02—Neural networks
- G06N3/08—Learning methods
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/20—Supervised data analysis
Landscapes
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Theoretical Computer Science (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Evolutionary Biology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Data Mining & Analysis (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Evolutionary Computation (AREA)
- Artificial Intelligence (AREA)
- Software Systems (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Databases & Information Systems (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Bioethics (AREA)
- Mathematical Physics (AREA)
- Biomedical Technology (AREA)
- Computational Linguistics (AREA)
- General Physics & Mathematics (AREA)
- Computing Systems (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Machine Translation (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263297679P | 2022-01-07 | 2022-01-07 | |
| US202263320067P | 2022-03-15 | 2022-03-15 | |
| US202263338398P | 2022-05-04 | 2022-05-04 | |
| US202263338433P | 2022-05-04 | 2022-05-04 | |
| US202263339450P | 2022-05-07 | 2022-05-07 | |
| US202263398222P | 2022-08-15 | 2022-08-15 | |
| US18/046,849 US20230268026A1 (en) | 2022-01-07 | 2022-10-14 | Designing biomolecule sequence variants with pre-specified attributes |
| PCT/US2023/060167 WO2023133462A1 (en) | 2022-01-07 | 2023-01-05 | Designing biomolecule sequence variants with pre-specified attributes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2024008515A true MX2024008515A (es) | 2024-08-27 |
Family
ID=85227256
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2024008515A MX2024008515A (es) | 2022-01-07 | 2023-01-05 | Diseño de variantes de secuencia de biomolécula con atributos especificados previamente. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20230268026A1 (https=) |
| EP (1) | EP4460827A1 (https=) |
| JP (1) | JP2025504384A (https=) |
| KR (1) | KR20240141868A (https=) |
| AU (1) | AU2023204806A1 (https=) |
| CA (1) | CA3247366A1 (https=) |
| IL (1) | IL313957A (https=) |
| MX (1) | MX2024008515A (https=) |
| WO (1) | WO2023133462A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12282941B2 (en) * | 2022-06-30 | 2025-04-22 | Constant Contact, Inc. | Email subject line generation method |
| CN115747089A (zh) * | 2022-07-06 | 2023-03-07 | 河南省巴饲福微生物技术研究院 | 一种生产谷胱甘肽的重组酿酒酵母菌及其构建方法 |
| US20240047006A1 (en) * | 2022-07-07 | 2024-02-08 | Lurong Pan | Artificial intelligence system and method for designing protein sequences |
| WO2025058962A1 (en) * | 2023-09-11 | 2025-03-20 | Absci Corporation | High-throughput methods for kinetic characterization, quantifying and optimizing antibodies and antibody fragments expression in bacteria |
| CN117079716B (zh) * | 2023-09-13 | 2024-04-05 | 江苏运动健康研究院 | 一种基于基因检测的肿瘤用药方案的深度学习预测方法 |
| CN116994654B (zh) * | 2023-09-27 | 2023-12-29 | 北京立康生命科技有限公司 | 一种用于鉴定与mhc-i/hla-i类结合及tcr识别肽段的方法、设备及存储介质 |
| US20250109209A1 (en) | 2023-10-03 | 2025-04-03 | Absci Corporation | Tl1a associated antibody compositions and methods of use |
| WO2025122885A1 (en) | 2023-12-08 | 2025-06-12 | Absci Corporation | Anti-her2 associated antibody compositions designed by artificial intelligence and methods of use |
| WO2025144700A1 (en) | 2023-12-27 | 2025-07-03 | Absci Corporation | Nanobody library screening using bacterial surface display |
| WO2025155628A1 (en) * | 2024-01-16 | 2025-07-24 | The Regents Of The University Of California | Interpretable deep learning predicts chemoresistance |
| WO2025170869A1 (en) * | 2024-02-06 | 2025-08-14 | Aikium Inc. | Multi-objective designed molecules and generation thereof |
| US20250279158A1 (en) * | 2024-02-29 | 2025-09-04 | Lurong Pan | Computer-assisted method and system for evaluating and modifying immunogenicity of protein sequences using a protein large language model |
| WO2025255259A1 (en) * | 2024-06-06 | 2025-12-11 | Generate Biomedicines, Inc. | Machine learning-guided generation of cross-reactive neutralizing antigen binding molecules against viral proteins |
| WO2026019845A1 (en) * | 2024-07-16 | 2026-01-22 | Hepta Bio, Inc. | Generalizable transformer for disease state classification from liquid biopsies |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8178338B2 (en) | 2005-07-01 | 2012-05-15 | The Regents Of The University Of California | Inducible expression vectors and methods of use thereof |
| CN107119095B (zh) | 2008-01-03 | 2022-07-05 | 康乃尔研究基金会有限公司 | 原核生物中的糖基化蛋白表达 |
| WO2017106583A1 (en) | 2015-12-15 | 2017-06-22 | Absci, Llc | Cytoplasmic expression system |
| US20150353940A1 (en) | 2013-08-05 | 2015-12-10 | Absci, Llc | Vectors for use in an inducible coexpression system |
| EP3924971A1 (en) | 2019-02-11 | 2021-12-22 | Flagship Pioneering Innovations VI, LLC | Machine learning guided polypeptide analysis |
| WO2020208555A1 (en) * | 2019-04-09 | 2020-10-15 | Eth Zurich | Systems and methods to classify antibodies |
| EP4008006A1 (en) | 2019-08-02 | 2022-06-08 | Flagship Pioneering Innovations VI, LLC | Machine learning guided polypeptide design |
| MX2022008801A (es) | 2020-01-15 | 2022-11-07 | Absci Corp | Enriquecimiento de células específico de la actividad. |
| JP2023513578A (ja) | 2020-02-11 | 2023-03-31 | アブサイ コーポレーション | 近接アッセイ |
-
2022
- 2022-10-14 US US18/046,849 patent/US20230268026A1/en active Pending
-
2023
- 2023-01-05 KR KR1020247026560A patent/KR20240141868A/ko active Pending
- 2023-01-05 EP EP23705152.9A patent/EP4460827A1/en active Pending
- 2023-01-05 WO PCT/US2023/060167 patent/WO2023133462A1/en not_active Ceased
- 2023-01-05 MX MX2024008515A patent/MX2024008515A/es unknown
- 2023-01-05 JP JP2024541017A patent/JP2025504384A/ja active Pending
- 2023-01-05 IL IL313957A patent/IL313957A/en unknown
- 2023-01-05 CA CA3247366A patent/CA3247366A1/en active Pending
- 2023-01-05 AU AU2023204806A patent/AU2023204806A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20230268026A1 (en) | 2023-08-24 |
| WO2023133462A1 (en) | 2023-07-13 |
| IL313957A (en) | 2024-08-01 |
| CA3247366A1 (en) | 2023-07-13 |
| KR20240141868A (ko) | 2024-09-27 |
| JP2025504384A (ja) | 2025-02-12 |
| EP4460827A1 (en) | 2024-11-13 |
| AU2023204806A1 (en) | 2024-07-25 |
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