JP2025503641A5 - - Google Patents

Info

Publication number
JP2025503641A5
JP2025503641A5 JP2024541159A JP2024541159A JP2025503641A5 JP 2025503641 A5 JP2025503641 A5 JP 2025503641A5 JP 2024541159 A JP2024541159 A JP 2024541159A JP 2024541159 A JP2024541159 A JP 2024541159A JP 2025503641 A5 JP2025503641 A5 JP 2025503641A5
Authority
JP
Japan
Application number
JP2024541159A
Other languages
Japanese (ja)
Other versions
JPWO2023133543A5 (https=
JP2025503641A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/060288 external-priority patent/WO2023133543A1/en
Publication of JP2025503641A publication Critical patent/JP2025503641A/ja
Publication of JP2025503641A5 publication Critical patent/JP2025503641A5/ja
Publication of JPWO2023133543A5 publication Critical patent/JPWO2023133543A5/ja
Pending legal-status Critical Current

Links

JP2024541159A 2022-01-10 2023-01-09 Ras阻害剤 Pending JP2025503641A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263298098P 2022-01-10 2022-01-10
US63/298,098 2022-01-10
PCT/US2023/060288 WO2023133543A1 (en) 2022-01-10 2023-01-09 Ras inhibitors

Publications (3)

Publication Number Publication Date
JP2025503641A JP2025503641A (ja) 2025-02-04
JP2025503641A5 true JP2025503641A5 (https=) 2026-01-19
JPWO2023133543A5 JPWO2023133543A5 (https=) 2026-01-19

Family

ID=85199574

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024541159A Pending JP2025503641A (ja) 2022-01-10 2023-01-09 Ras阻害剤

Country Status (16)

Country Link
US (1) US20250197423A1 (https=)
EP (1) EP4463231A1 (https=)
JP (1) JP2025503641A (https=)
KR (1) KR20240132492A (https=)
CN (2) CN118922423A (https=)
AR (1) AR128234A1 (https=)
AU (1) AU2023204824A1 (https=)
CA (1) CA3246887A1 (https=)
CL (2) CL2024002041A1 (https=)
CO (1) CO2024010814A2 (https=)
CR (1) CR20240276A (https=)
IL (1) IL314033A (https=)
MX (1) MX2024008561A (https=)
PE (1) PE20241892A1 (https=)
TW (1) TW202330553A (https=)
WO (1) WO2023133543A1 (https=)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2023003060A (es) 2020-09-15 2023-04-05 Revolution Medicines Inc Derivados indolicos como inhibidores de ras en el tratamiento del cancer.
WO2023240263A1 (en) * 2022-06-10 2023-12-14 Revolution Medicines, Inc. Macrocyclic ras inhibitors
CN119546613A (zh) * 2022-07-08 2025-02-28 豪夫迈·罗氏有限公司 可用作kras抑制剂的大环化合物
CN119522225A (zh) 2022-09-29 2025-02-25 广州嘉越医药科技有限公司 大环衍生物及其应用
WO2024104364A1 (zh) * 2022-11-16 2024-05-23 杭州阿诺生物医药科技有限公司 一种pan-KRAS抑制剂化合物
CR20250329A (es) 2023-02-14 2025-09-12 Hoffmann La Roche Compuestos tricíclicos para el tratamiento del cáncer
EP4687905A1 (en) 2023-03-30 2026-02-11 Revolution Medicines, Inc. Compositions for inducing ras gtp hydrolysis and uses thereof
CN121263418A (zh) 2023-04-07 2026-01-02 锐新医药公司 大环ras抑制剂
AU2024265078A1 (en) 2023-05-04 2025-12-11 Revolution Medicines, Inc. Combination therapy for a ras related disease or disorder
IL326136A (en) 2023-08-07 2026-03-01 Revolution Medicines Inc RMC-6291 for use in the treatment of a disease or disorder associated with the RAS protein
US20250154171A1 (en) 2023-10-12 2025-05-15 Revolution Medicines, Inc. Ras inhibitors
WO2025104149A1 (en) * 2023-11-16 2025-05-22 F. Hoffmann-La Roche Ag Macrocyclic compounds as kras mutant inhibitors for the treatment of cancer
WO2025171296A1 (en) 2024-02-09 2025-08-14 Revolution Medicines, Inc. Ras inhibitors
WO2025213065A1 (en) * 2024-04-05 2025-10-09 Revolution Medicines, Inc. Peptide conjugates
WO2025217307A1 (en) 2024-04-09 2025-10-16 Revolution Medicines, Inc. Methods for predicting response to a ras(on) inhibitor and combination therapies
WO2025240847A1 (en) 2024-05-17 2025-11-20 Revolution Medicines, Inc. Ras inhibitors
US20250375445A1 (en) 2024-06-07 2025-12-11 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder
WO2025265060A1 (en) 2024-06-21 2025-12-26 Revolution Medicines, Inc. Therapeutic compositions and methods for managing treatment-related effects
WO2026006747A1 (en) 2024-06-28 2026-01-02 Revolution Medicines, Inc. Ras inhibitors
WO2026015825A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Use of ras inhibitor for treating pancreatic cancer
WO2026015790A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015796A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015801A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026050446A1 (en) 2024-08-29 2026-03-05 Revolution Medicines, Inc. Ras inhibitors
WO2026072904A2 (en) 2024-09-26 2026-04-02 Revolution Medicines, Inc. Compositions and methods for treating lung cancer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2022005359A (es) 2019-11-04 2022-06-02 Revolution Medicines Inc Inhibidores de ras.
CN120699039A (zh) * 2019-11-04 2025-09-26 锐新医药公司 Ras抑制剂
WO2021091956A1 (en) * 2019-11-04 2021-05-14 Revolution Medicines, Inc. Ras inhibitors
TW202304452A (zh) * 2021-04-09 2023-02-01 美商銳新醫藥公司 Sos1抑制劑與ras抑制劑於治療癌症之用途
CA3217393A1 (en) * 2021-05-05 2022-11-10 Elena S. Koltun Ras inhibitors
MX2023013912A (es) * 2021-05-25 2024-02-12 Revolution Medicines Inc Metodos para inhibir ras.

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