JP2025502811A5 - - Google Patents
Info
- Publication number
- JP2025502811A5 JP2025502811A5 JP2024539661A JP2024539661A JP2025502811A5 JP 2025502811 A5 JP2025502811 A5 JP 2025502811A5 JP 2024539661 A JP2024539661 A JP 2024539661A JP 2024539661 A JP2024539661 A JP 2024539661A JP 2025502811 A5 JP2025502811 A5 JP 2025502811A5
- Authority
- JP
- Japan
- Prior art keywords
- chains
- nucleic acid
- stranded dna
- cytosine
- dna fragments
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163294640P | 2021-12-29 | 2021-12-29 | |
| US63/294,640 | 2021-12-29 | ||
| PCT/US2022/082476 WO2023129965A2 (en) | 2021-12-29 | 2022-12-28 | Detection of genetic and epigenetic information in a single workflow |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025502811A JP2025502811A (ja) | 2025-01-28 |
| JP2025502811A5 true JP2025502811A5 (enExample) | 2025-12-16 |
Family
ID=87000276
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024539661A Pending JP2025502811A (ja) | 2021-12-29 | 2022-12-28 | 単一ワークフローにおける遺伝子情報及びエピジェネティック情報の検出 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20250051840A1 (enExample) |
| EP (1) | EP4457357A4 (enExample) |
| JP (1) | JP2025502811A (enExample) |
| CN (1) | CN118541493A (enExample) |
| WO (1) | WO2023129965A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025104430A1 (en) * | 2023-11-14 | 2025-05-22 | Tagomics Ltd | Profiling method for determining epigenetic modifications |
| WO2025128727A1 (en) * | 2023-12-12 | 2025-06-19 | Foundation Medicine, Inc. | Methods and systems for preparing a sequencing library |
| WO2025160495A1 (en) * | 2024-01-26 | 2025-07-31 | Cornell University | Hematopoietic stem cells and uses thereof in treating cancer |
| WO2025235365A1 (en) * | 2024-05-08 | 2025-11-13 | Freenome Holdings, Inc. | Methods and systems for improved methylation sequencing |
| WO2026022118A1 (en) | 2024-07-23 | 2026-01-29 | Qiagen Gmbh | Method of detecting methylated nucleic acids |
| WO2026043738A1 (en) * | 2024-08-20 | 2026-02-26 | Natera, Inc. | Improved method for methylation biomarker generation and analysis |
| US12509733B1 (en) | 2025-04-07 | 2025-12-30 | Inivata Ltd. | Methods and systems for detecting a primary disease |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009132315A1 (en) * | 2008-04-24 | 2009-10-29 | Life Technologies Corporation | Method of sequencing and mapping target nucleic acids |
| WO2010048337A2 (en) * | 2008-10-22 | 2010-04-29 | Illumina, Inc. | Preservation of information related to genomic dna methylation |
| US20150011396A1 (en) * | 2012-07-09 | 2015-01-08 | Benjamin G. Schroeder | Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing |
| NZ765943A (en) * | 2018-01-08 | 2022-10-28 | Ludwig Inst For Cancer Res Ltd | Bisulfite-free, base-resolution identification of cytosine modifications |
| CA3225385A1 (en) * | 2021-07-12 | 2023-01-19 | The Trustees Of The University Of Pennsylvania | Modified adapters for enzymatic dna deamination and methods of use thereof for epigenetic sequencing of free and immobilized dna |
-
2022
- 2022-12-28 EP EP22917534.4A patent/EP4457357A4/en active Pending
- 2022-12-28 JP JP2024539661A patent/JP2025502811A/ja active Pending
- 2022-12-28 CN CN202280087109.6A patent/CN118541493A/zh active Pending
- 2022-12-28 WO PCT/US2022/082476 patent/WO2023129965A2/en not_active Ceased
- 2022-12-28 US US18/722,508 patent/US20250051840A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2025502811A5 (enExample) | ||
| US11162094B2 (en) | Capture methodologies for circulating cell free DNA | |
| JP7008407B2 (ja) | ヌクレアーゼ、リガーゼ、ポリメラーゼ、及び配列決定反応の組み合わせを用いた、核酸配列、発現、コピー、またはｄｎａのメチル化変化の識別及び計数方法 | |
| US10760123B2 (en) | Sequential sequencing | |
| US20150126376A1 (en) | Compositions and methods for sensitive mutation detection in nucleic acid molecules | |
| US20220267848A1 (en) | Detection and quantification of rare variants with low-depth sequencing via selective allele enrichment or depletion | |
| JP2003517309A (ja) | 単一ヌクレオチドの変異及びジェノタイピングの決定方法 | |
| US11261479B2 (en) | Methods and compositions for enrichment of target nucleic acids | |
| WO2019062614A1 (en) | METHOD FOR AMPLIFYING TARGET NUCLEIC ACID | |
| JP2020530270A (ja) | ゲノム再編成検出のための配列決定方法 | |
| JP2005518216A (ja) | 融解温度依存ｄｎａ増幅 | |
| JP6906504B2 (ja) | 短いホモポリマー反復の改良された検出 | |
| CN105247071B (zh) | 使用等位基因特异的反应性引物的核酸扩增方法 | |
| KR102265417B1 (ko) | 단일염기다형성 다중 분석용 프라이머 | |
| JP2007530026A (ja) | 核酸配列決定 | |
| US20170275675A1 (en) | Detection method and kit of base mutation, and method for limiting pcr amplification of nucleic acid sample | |
| JP2022533088A5 (enExample) | ||
| WO2012032510A1 (en) | Primers for amplifying dna and methods of selecting same | |
| CN114929896B (zh) | 用于多重靶扩增pcr的有效方法和组合物 | |
| KR101856205B1 (ko) | 핵산의 대립형질 특이적 프라이머 및 이를 이용한 유전형 판별 방법 | |
| JP2018533943A (ja) | 一塩基多型検出用キット及び方法 | |
| CN110938681A (zh) | 等位基因核酸富集和检测方法 | |
| KR102768600B1 (ko) | 대립유전자 분석을 위한 Miso-Winglet 구조의 프라이머 쌍 및 이를 이용한 단일염기서열변이의 대립유전자를 분석하는 방법 | |
| WO2001032932A2 (en) | Method of identifying a nucleic acid sequence | |
| US20190119746A1 (en) | Oligonucleotides for selective amplification of nucleic acids |