JP2025500404A5 - - Google Patents

Info

Publication number
JP2025500404A5
JP2025500404A5 JP2024537875A JP2024537875A JP2025500404A5 JP 2025500404 A5 JP2025500404 A5 JP 2025500404A5 JP 2024537875 A JP2024537875 A JP 2024537875A JP 2024537875 A JP2024537875 A JP 2024537875A JP 2025500404 A5 JP2025500404 A5 JP 2025500404A5
Authority
JP
Japan
Prior art keywords
pharmaceutically acceptable
acceptable salt
compound according
structural formula
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024537875A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025500404A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/053738 external-priority patent/WO2023122228A1/en
Publication of JP2025500404A publication Critical patent/JP2025500404A/ja
Publication of JP2025500404A5 publication Critical patent/JP2025500404A5/ja
Pending legal-status Critical Current

Links

JP2024537875A 2021-12-23 2022-12-21 新規オーリスタチン類似体およびその免疫複合体 Pending JP2025500404A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163293583P 2021-12-23 2021-12-23
US63/293,583 2021-12-23
PCT/US2022/053738 WO2023122228A1 (en) 2021-12-23 2022-12-21 Novel auristatin analogs and immunoconjugates thereof

Publications (2)

Publication Number Publication Date
JP2025500404A JP2025500404A (ja) 2025-01-09
JP2025500404A5 true JP2025500404A5 (https=) 2026-01-06

Family

ID=86903604

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024537875A Pending JP2025500404A (ja) 2021-12-23 2022-12-21 新規オーリスタチン類似体およびその免疫複合体

Country Status (10)

Country Link
US (1) US20250049937A1 (https=)
EP (1) EP4453000A4 (https=)
JP (1) JP2025500404A (https=)
KR (1) KR20240152826A (https=)
CN (1) CN118829645A (https=)
AU (1) AU2022422015A1 (https=)
CA (1) CA3241878A1 (https=)
IL (1) IL313784A (https=)
TW (1) TW202328162A (https=)
WO (1) WO2023122228A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025067221A1 (zh) * 2023-09-26 2025-04-03 上海齐鲁制药研究中心有限公司 奥瑞他汀衍生物及其抗体药物偶联物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015017552A1 (en) * 2013-08-01 2015-02-05 Agensys, Inc. Antibody drug conjugates (adc) that bind to cd37 proteins
CA2951368A1 (en) * 2014-06-13 2015-12-17 Novartis Ag Auristatin derivatives and conjugates thereof
CA3205824A1 (en) * 2014-10-09 2016-04-14 Genzyme Corporation Glycoengineered antibody drug conjugates
US20190194315A1 (en) * 2015-06-17 2019-06-27 Novartis Ag Antibody drug conjugates
CN119241554A (zh) * 2017-12-15 2025-01-03 四川科伦博泰生物医药股份有限公司 生物活性物偶联物及其制备方法和用途

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