JP2025500342A5 - - Google Patents
Info
- Publication number
- JP2025500342A5 JP2025500342A5 JP2024537359A JP2024537359A JP2025500342A5 JP 2025500342 A5 JP2025500342 A5 JP 2025500342A5 JP 2024537359 A JP2024537359 A JP 2024537359A JP 2024537359 A JP2024537359 A JP 2024537359A JP 2025500342 A5 JP2025500342 A5 JP 2025500342A5
- Authority
- JP
- Japan
- Prior art keywords
- drug conjugate
- note
- aryl
- heteroaryl
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163292101P | 2021-12-21 | 2021-12-21 | |
| US63/292,101 | 2021-12-21 | ||
| PCT/IB2022/000772 WO2023118961A1 (en) | 2021-12-21 | 2022-12-20 | Antibody drug conjugates comprising toxins with polar groups and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025500342A JP2025500342A (ja) | 2025-01-09 |
| JP2025500342A5 true JP2025500342A5 (https=) | 2026-01-06 |
Family
ID=86766932
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024537359A Pending JP2025500342A (ja) | 2021-12-21 | 2022-12-20 | 極性基を有する毒素を含む抗体薬物コンジュゲート及びその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20230190939A1 (https=) |
| EP (1) | EP4452328A1 (https=) |
| JP (1) | JP2025500342A (https=) |
| KR (1) | KR20240127409A (https=) |
| CN (2) | CN119838020A (https=) |
| WO (1) | WO2023118961A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112930350A (zh) | 2018-10-31 | 2021-06-08 | 尹图赛利有限公司 | 稠合杂环苯并二氮杂䓬衍生物及其用途 |
| US20250239582A1 (en) | 2024-01-19 | 2025-07-24 | 24M Technologies, Inc. | Systems and methods for preparing semi-solid electrodes |
| WO2025214466A1 (en) * | 2024-04-12 | 2025-10-16 | BeiGene Guangzhou Biologics Manufacturing Co., Ltd. | Targeted pyrrolobenzodiazapine conjugates |
| WO2026059501A1 (en) * | 2024-09-13 | 2026-03-19 | Hummingbird Bioscience Pte. Ltd. | Linker moieties |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5843937A (en) * | 1996-05-23 | 1998-12-01 | Panorama Research, Inc. | DNA-binding indole derivatives, their prodrugs and immunoconjugates as anticancer agents |
| CA2891280C (en) * | 2012-11-24 | 2018-03-20 | Hangzhou Dac Biotech Co., Ltd. | Hydrophilic linkers and their uses for conjugation of drugs to cell binding molecules |
| GB201617466D0 (en) * | 2016-10-14 | 2016-11-30 | Medimmune Ltd | Pyrrolobenzodiazepine conjugates |
| CN112930350A (zh) * | 2018-10-31 | 2021-06-08 | 尹图赛利有限公司 | 稠合杂环苯并二氮杂䓬衍生物及其用途 |
| KR102503143B1 (ko) * | 2019-03-06 | 2023-02-24 | 주식회사 레고켐 바이오사이언스 | 인간 dlk1에 대한 항체를 포함하는 항체 약물 접합체 및 이의 용도 |
-
2022
- 2022-12-20 JP JP2024537359A patent/JP2025500342A/ja active Pending
- 2022-12-20 US US18/084,739 patent/US20230190939A1/en active Pending
- 2022-12-20 CN CN202411879063.9A patent/CN119838020A/zh active Pending
- 2022-12-20 KR KR1020247024345A patent/KR20240127409A/ko active Pending
- 2022-12-20 WO PCT/IB2022/000772 patent/WO2023118961A1/en not_active Ceased
- 2022-12-20 EP EP22910281.9A patent/EP4452328A1/en active Pending
- 2022-12-20 CN CN202280084624.9A patent/CN118414170A/zh active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2025500342A5 (https=) | ||
| TWI710574B (zh) | 抗訊號調節蛋白α(SIRPα)抗體 | |
| AU2016232839B2 (en) | CD48 antibodies and conjugates thereof | |
| CN107849133B (zh) | 抗cd166抗体、可活化抗cd166抗体及其使用方法 | |
| JP2022064924A (ja) | 抗pd-1抗体、活性化可能抗pd-1抗体、およびその使用方法 | |
| JP2023551355A (ja) | 抗腫瘍化合物並びにその調製方法及び使用 | |
| Maleki et al. | Future prospects of monoclonal antibodies as magic bullets in immunotherapy | |
| CA2890256A1 (en) | Anti-il-13 receptor alpha 2 antibodies and antibody-drug conjugates | |
| JP2023505708A (ja) | 抗クローディン抗体薬物複合体及びその医薬用途 | |
| US20250032633A1 (en) | Antibody-drug conjugate and application thereof | |
| CN110799540A (zh) | 多特异性抗体及其制备和使用方法 | |
| CN115298220A (zh) | 抗体-药物偶联物及其医药用途 | |
| AU2026202052A1 (en) | Anti-c-Met antibody drug conjugates | |
| CA3261633A1 (en) | ANTIBODY-DRUG CONJUGATE, PREPARATION METHOD AND USE | |
| JP2023528344A (ja) | がんの治療のための抗b7h3抗体 | |
| IL314567A (en) | Drug-conjugated antibody to HER3 and its use | |
| CN113549127A (zh) | 长春新碱及其抗体偶联物、其制备方法和医药用途 | |
| TW202342025A (zh) | Gpc3抗體藥物偶聯物及其用途 | |
| CN116568707A (zh) | 一种抗体药物偶联物及其医药用途 | |
| CA3225975A1 (en) | Drug conjugate of eribulin derivative | |
| US20240390509A1 (en) | Antibody-drug conjugate, preparation method therefor, and pharmaceutical use thereof | |
| WO2024188339A1 (zh) | 抗liv-1抗体和抗liv-1抗体药物偶联物及其药物用途 | |
| TWI908142B (zh) | Nectin-4抗體及抗體藥物結合物 | |
| WO2026057074A1 (zh) | 抗liv-1抗体-药物偶联物的组合疗法 | |
| US20250197501A1 (en) | Recombinant antibody, immunoconjugate comprising the same, and uses thereof in treating cancers |