JP2025500342A5 - - Google Patents

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Publication number
JP2025500342A5
JP2025500342A5 JP2024537359A JP2024537359A JP2025500342A5 JP 2025500342 A5 JP2025500342 A5 JP 2025500342A5 JP 2024537359 A JP2024537359 A JP 2024537359A JP 2024537359 A JP2024537359 A JP 2024537359A JP 2025500342 A5 JP2025500342 A5 JP 2025500342A5
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JP
Japan
Prior art keywords
drug conjugate
note
aryl
heteroaryl
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024537359A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025500342A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2022/000772 external-priority patent/WO2023118961A1/en
Publication of JP2025500342A publication Critical patent/JP2025500342A/ja
Publication of JP2025500342A5 publication Critical patent/JP2025500342A5/ja
Pending legal-status Critical Current

Links

JP2024537359A 2021-12-21 2022-12-20 極性基を有する毒素を含む抗体薬物コンジュゲート及びその使用 Pending JP2025500342A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163292101P 2021-12-21 2021-12-21
US63/292,101 2021-12-21
PCT/IB2022/000772 WO2023118961A1 (en) 2021-12-21 2022-12-20 Antibody drug conjugates comprising toxins with polar groups and uses thereof

Publications (2)

Publication Number Publication Date
JP2025500342A JP2025500342A (ja) 2025-01-09
JP2025500342A5 true JP2025500342A5 (https=) 2026-01-06

Family

ID=86766932

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024537359A Pending JP2025500342A (ja) 2021-12-21 2022-12-20 極性基を有する毒素を含む抗体薬物コンジュゲート及びその使用

Country Status (6)

Country Link
US (1) US20230190939A1 (https=)
EP (1) EP4452328A1 (https=)
JP (1) JP2025500342A (https=)
KR (1) KR20240127409A (https=)
CN (2) CN119838020A (https=)
WO (1) WO2023118961A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112930350A (zh) 2018-10-31 2021-06-08 尹图赛利有限公司 稠合杂环苯并二氮杂䓬衍生物及其用途
US20250239582A1 (en) 2024-01-19 2025-07-24 24M Technologies, Inc. Systems and methods for preparing semi-solid electrodes
WO2025214466A1 (en) * 2024-04-12 2025-10-16 BeiGene Guangzhou Biologics Manufacturing Co., Ltd. Targeted pyrrolobenzodiazapine conjugates
WO2026059501A1 (en) * 2024-09-13 2026-03-19 Hummingbird Bioscience Pte. Ltd. Linker moieties

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843937A (en) * 1996-05-23 1998-12-01 Panorama Research, Inc. DNA-binding indole derivatives, their prodrugs and immunoconjugates as anticancer agents
CA2891280C (en) * 2012-11-24 2018-03-20 Hangzhou Dac Biotech Co., Ltd. Hydrophilic linkers and their uses for conjugation of drugs to cell binding molecules
GB201617466D0 (en) * 2016-10-14 2016-11-30 Medimmune Ltd Pyrrolobenzodiazepine conjugates
CN112930350A (zh) * 2018-10-31 2021-06-08 尹图赛利有限公司 稠合杂环苯并二氮杂䓬衍生物及其用途
KR102503143B1 (ko) * 2019-03-06 2023-02-24 주식회사 레고켐 바이오사이언스 인간 dlk1에 대한 항체를 포함하는 항체 약물 접합체 및 이의 용도

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