JP2025029046A5 - - Google Patents
Info
- Publication number
- JP2025029046A5 JP2025029046A5 JP2024209068A JP2024209068A JP2025029046A5 JP 2025029046 A5 JP2025029046 A5 JP 2025029046A5 JP 2024209068 A JP2024209068 A JP 2024209068A JP 2024209068 A JP2024209068 A JP 2024209068A JP 2025029046 A5 JP2025029046 A5 JP 2025029046A5
- Authority
- JP
- Japan
- Prior art keywords
- occupied
- antigen
- kabat positions
- antibody fragment
- humanized antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962803334P | 2019-02-08 | 2019-02-08 | |
| US62/803,334 | 2019-02-08 | ||
| US201962813124P | 2019-03-03 | 2019-03-03 | |
| US62/813,124 | 2019-03-03 | ||
| US201962855434P | 2019-05-31 | 2019-05-31 | |
| US62/855,434 | 2019-05-31 | ||
| JP2021569259A JP7681316B2 (ja) | 2019-02-08 | 2020-02-07 | タウを認識する抗体 |
| PCT/US2020/017357 WO2020163817A1 (en) | 2019-02-08 | 2020-02-07 | Antibodies recognizing tau |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021569259A Division JP7681316B2 (ja) | 2019-02-08 | 2020-02-07 | タウを認識する抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2025029046A JP2025029046A (ja) | 2025-03-05 |
| JP2025029046A5 true JP2025029046A5 (https=) | 2025-10-08 |
| JP7843068B2 JP7843068B2 (ja) | 2026-04-09 |
Family
ID=71947192
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021569259A Active JP7681316B2 (ja) | 2019-02-08 | 2020-02-07 | タウを認識する抗体 |
| JP2024209068A Active JP7843068B2 (ja) | 2019-02-08 | 2024-11-29 | タウを認識する抗体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021569259A Active JP7681316B2 (ja) | 2019-02-08 | 2020-02-07 | タウを認識する抗体 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20220275067A1 (https=) |
| EP (1) | EP3921343A4 (https=) |
| JP (2) | JP7681316B2 (https=) |
| KR (1) | KR20210125037A (https=) |
| CN (2) | CN119954947A (https=) |
| AU (1) | AU2020219374A1 (https=) |
| BR (1) | BR112021015501A2 (https=) |
| CA (1) | CA3128392A1 (https=) |
| CO (1) | CO2021011140A2 (https=) |
| IL (1) | IL285444A (https=) |
| MX (1) | MX2021009440A (https=) |
| PE (1) | PE20211709A1 (https=) |
| SG (1) | SG11202106717PA (https=) |
| WO (1) | WO2020163817A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10501531B2 (en) | 2013-03-13 | 2019-12-10 | Prothena Biosciences Limited | Tau immunotherapy |
| MX2018013386A (es) | 2016-05-02 | 2019-02-28 | Prothena Biosciences Ltd | Anticuerpos que reconocen tau. |
| PT3452507T (pt) | 2016-05-02 | 2022-12-20 | Prothena Biosciences Ltd | Imunoterapia anti-tau |
| MY198194A (en) | 2016-05-02 | 2023-08-09 | Prothena Biosciences Ltd | Antibodies Recognizing Tau |
| KR102784294B1 (ko) | 2017-05-02 | 2025-03-19 | 프로테나 바이오사이언시즈 리미티드 | 타우 인식 항체 |
| CN111201030B (zh) | 2017-07-25 | 2024-11-01 | 真和制药有限公司 | 通过阻断tim-3和其配体的相互作用治疗癌症 |
| US12018087B2 (en) | 2018-08-02 | 2024-06-25 | Dyne Therapeutics, Inc. | Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject |
| US12370264B1 (en) | 2018-08-02 | 2025-07-29 | Dyne Therapeutics, Inc. | Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject |
| US12097263B2 (en) | 2018-08-02 | 2024-09-24 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| US11911484B2 (en) | 2018-08-02 | 2024-02-27 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| WO2020160156A2 (en) | 2019-01-30 | 2020-08-06 | Immutics, Inc. | Anti-gal3 antibodies and uses thereof |
| WO2020163817A1 (en) * | 2019-02-08 | 2020-08-13 | Prothena Biosciences Limited | Antibodies recognizing tau |
| JP7630834B2 (ja) | 2019-03-03 | 2025-02-18 | プロセナ バイオサイエンシーズ リミテッド | タウ認識抗体 |
| EP4157338A4 (en) | 2020-05-26 | 2024-11-13 | TrueBinding, Inc. | METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING |
| CA3226301A1 (en) * | 2021-07-09 | 2023-01-12 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| US11969475B2 (en) | 2021-07-09 | 2024-04-30 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy |
| US11633498B2 (en) | 2021-07-09 | 2023-04-25 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| IL316143A (en) | 2022-04-15 | 2024-12-01 | Dyne Therapeutics Inc | Muscle targeting complexes and formulations for the treatment of myotonic dystrophy |
| JP2023175325A (ja) * | 2022-05-30 | 2023-12-12 | 学校法人順天堂 | タウオパチーの鑑別診断法 |
| WO2025198916A1 (en) * | 2024-03-16 | 2025-09-25 | Abbvie Inc. | Anti-tau antibodies |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001018546A2 (en) * | 1999-09-09 | 2001-03-15 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Screening for inhibitors of 'paired helical filaments' |
| US8754034B2 (en) * | 2009-02-06 | 2014-06-17 | The Regents Of The University Of California | Structure-based design of peptide inhibitors of amyloid fibrillation |
| JP2013500326A (ja) * | 2009-07-30 | 2013-01-07 | ファイザー バクシーンズ エルエルシー | 抗原性タウペプチドおよびその使用 |
| US20120244174A1 (en) * | 2011-01-31 | 2012-09-27 | Intellect Neurosciences Inc. | Treatment of tauopathies |
| GB201111361D0 (en) | 2011-07-04 | 2011-08-17 | Nordic Bioscience As | Biochemical markers for neurodegenerative conditions |
| ME03008B (me) | 2011-09-19 | 2018-10-20 | Axon Neuroscience Se | Terapija na osnovu proteina i dijagnoza patologije u којој posreduje tau u alcнajмerovoj bolesti |
| US9738709B2 (en) * | 2011-10-21 | 2017-08-22 | Ohio State Innovation Foundation | Methylated peptides derived from tau protein and their antibodies for diagnosis and therapy of alzheimer's disease |
| US9200068B2 (en) * | 2012-12-18 | 2015-12-01 | Regents Of The University Of Minnesota | Compositions and methods related to tauopathy |
| US10501531B2 (en) * | 2013-03-13 | 2019-12-10 | Prothena Biosciences Limited | Tau immunotherapy |
| US20150253341A1 (en) * | 2014-02-10 | 2015-09-10 | Merck Sharp & Dohme Corp. | Quantification of tau in biological samples by immunoaffinity enrichment and mass spectrometry |
| NZ775762A (en) * | 2015-06-05 | 2025-02-28 | Genentech Inc | Anti-tau antibodies and methods of use |
| US20190330335A1 (en) * | 2015-10-06 | 2019-10-31 | Alector Llc | Anti-trem2 antibodies and methods of use thereof |
| JP7165995B2 (ja) * | 2017-02-21 | 2022-11-07 | アールイーエムディー バイオセラピューティクス，インコーポレイテッド | 細胞傷害性ｔリンパ球抗原－４（ｃｔｌａ－４）に結合する抗体を使用した癌治療 |
| WO2020163817A1 (en) * | 2019-02-08 | 2020-08-13 | Prothena Biosciences Limited | Antibodies recognizing tau |
-
2020
- 2020-02-07 WO PCT/US2020/017357 patent/WO2020163817A1/en not_active Ceased
- 2020-02-07 EP EP20753068.4A patent/EP3921343A4/en active Pending
- 2020-02-07 SG SG11202106717PA patent/SG11202106717PA/en unknown
- 2020-02-07 CN CN202510128272.8A patent/CN119954947A/zh active Pending
- 2020-02-07 CN CN202080018281.7A patent/CN113597431B/zh active Active
- 2020-02-07 BR BR112021015501-5A patent/BR112021015501A2/pt unknown
- 2020-02-07 PE PE2021001286A patent/PE20211709A1/es unknown
- 2020-02-07 US US17/429,288 patent/US20220275067A1/en active Pending
- 2020-02-07 JP JP2021569259A patent/JP7681316B2/ja active Active
- 2020-02-07 AU AU2020219374A patent/AU2020219374A1/en active Pending
- 2020-02-07 CA CA3128392A patent/CA3128392A1/en active Pending
- 2020-02-07 MX MX2021009440A patent/MX2021009440A/es unknown
- 2020-02-07 KR KR1020217028112A patent/KR20210125037A/ko active Pending
-
2021
- 2021-08-08 IL IL285444A patent/IL285444A/en unknown
- 2021-08-24 CO CONC2021/0011140A patent/CO2021011140A2/es unknown
-
2024
- 2024-11-29 JP JP2024209068A patent/JP7843068B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2025029046A5 (https=) | ||
| IL262726B1 (en) | Antibodies recognizing tau | |
| JP2023113836A5 (https=) | ||
| US12091458B2 (en) | Humanized antibodies against c-Kit | |
| JP2022520672A5 (https=) | ||
| EP3353213B1 (en) | Anti-mesothelin antibody and composition comprising the same | |
| JP2022506719A5 (https=) | ||
| JP2020508655A5 (https=) | ||
| JP2019525728A5 (https=) | ||
| JP2020520231A5 (https=) | ||
| JP2020513791A5 (https=) | ||
| JP2018510617A5 (https=) | ||
| JP2019525724A5 (https=) | ||
| JP2020536532A5 (https=) | ||
| RU2019121086A (ru) | Иммунотерапия с применением антител, связывающих лиганд 1 белка программируемой смерти клеток (PD-L1) | |
| JP2012525829A5 (https=) | ||
| JP2024527288A5 (https=) | ||
| JP2018509889A5 (https=) | ||
| JP2024520188A5 (https=) | ||
| JP2022549172A5 (https=) | ||
| RU2019121106A (ru) | Иммунотерапия с применением антител, связывающих белок 1 программируемой смерти клеток (pd-1) | |
| JP2021518748A5 (https=) | ||
| JP2025130076A5 (https=) | ||
| JP2025508042A5 (https=) | ||
| HK40117185A (en) | Humanized antibodies against c-kit |