JP2024540863A5 - - Google Patents

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Publication number
JP2024540863A5
JP2024540863A5 JP2024522065A JP2024522065A JP2024540863A5 JP 2024540863 A5 JP2024540863 A5 JP 2024540863A5 JP 2024522065 A JP2024522065 A JP 2024522065A JP 2024522065 A JP2024522065 A JP 2024522065A JP 2024540863 A5 JP2024540863 A5 JP 2024540863A5
Authority
JP
Japan
Prior art keywords
amino acid
seq
acid sequence
taa
multispecific antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024522065A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024540863A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2022/124961 external-priority patent/WO2023061417A1/en
Publication of JP2024540863A publication Critical patent/JP2024540863A/ja
Publication of JP2024540863A5 publication Critical patent/JP2024540863A5/ja
Pending legal-status Critical Current

Links

JP2024522065A 2021-10-12 2022-10-12 改善された治療指数を有するcd3標的化t細胞エンゲージャー Pending JP2024540863A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CNPCT/CN2021/123374 2021-10-12
CN2021123374 2021-10-12
CNPCT/CN2022/104995 2022-07-11
CN2022104995 2022-07-11
PCT/CN2022/124961 WO2023061417A1 (en) 2021-10-12 2022-10-12 Cd3-targeting t-cell engagers with improved therapeutic index

Publications (2)

Publication Number Publication Date
JP2024540863A JP2024540863A (ja) 2024-11-06
JP2024540863A5 true JP2024540863A5 (enExample) 2025-10-22

Family

ID=85987305

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024522065A Pending JP2024540863A (ja) 2021-10-12 2022-10-12 改善された治療指数を有するcd3標的化t細胞エンゲージャー

Country Status (5)

Country Link
US (1) US20240417469A1 (enExample)
EP (1) EP4415825A4 (enExample)
JP (1) JP2024540863A (enExample)
CN (1) CN118556083A (enExample)
WO (1) WO2023061417A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN122070305A (zh) * 2023-09-21 2026-05-19 艾科联生物科技(上海)有限公司 多特异性抗体及其用途
WO2025103425A1 (en) * 2023-11-15 2025-05-22 Concept To Medicine Biotech Co., Ltd. Multispecific antibodies and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY200973A (en) * 2017-04-11 2024-01-26 Inhibrx Inc Multispecific Polypeptide Constructs Having Constrained Cd3 Binding And Methods Of Using The Same
TW202010757A (zh) * 2018-04-11 2020-03-16 美商英伊布里克斯公司 具有經受限cd3結合的多重特異性多肽構築體以及相關方法及用途
WO2020023553A1 (en) * 2018-07-24 2020-01-30 Inhibrx, Inc. Multispecific polypeptide constructs containing a constrained cd3 binding domain and a receptor binding region and methods of using the same
JP2022501325A (ja) * 2018-09-28 2022-01-06 中外製薬株式会社 改変された抗体可変領域を含む抗原結合分子
CN113166261A (zh) * 2018-10-11 2021-07-23 印希比股份有限公司 B7h3单域抗体及其治疗性组合物
US12590169B2 (en) * 2018-10-11 2026-03-31 Inhibrx Biosciences, Inc. 5T4 single domain antibodies and therapeutic compositions thereof
CN110669137B (zh) * 2019-10-24 2021-07-16 高新 一种多特异性抗体及其制备方法和用途
EP4110820A4 (en) * 2020-02-25 2024-03-27 Gensun Biopharma Inc. Trispecific t cell engagers

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