JP2024540480A - 腎臓疾患の貧血を処置する方法 - Google Patents

腎臓疾患の貧血を処置する方法 Download PDF

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Publication number
JP2024540480A
JP2024540480A JP2024529330A JP2024529330A JP2024540480A JP 2024540480 A JP2024540480 A JP 2024540480A JP 2024529330 A JP2024529330 A JP 2024529330A JP 2024529330 A JP2024529330 A JP 2024529330A JP 2024540480 A JP2024540480 A JP 2024540480A
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JP
Japan
Prior art keywords
amino acid
seq
acid sequence
hjv
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024529330A
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English (en)
Japanese (ja)
Other versions
JP2024540480A5 (https=
Inventor
マクドナルド，ブライアン
クイゼル，ジョン
サベッジ，ウィル
ヤン，ホア
ユー，ジョナサン
ウー，ミン
ベコーニ，マリア
エム ペレス，ジェニファー
ミュラー，ベルンハルト
ポップ，アンドレアス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AbbVie Deutschland GmbH and Co KG
AbbVie Inc
Disc Medicine Inc
Original Assignee
AbbVie Deutschland GmbH and Co KG
AbbVie Inc
Disc Medicine Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AbbVie Deutschland GmbH and Co KG, AbbVie Inc, Disc Medicine Inc filed Critical AbbVie Deutschland GmbH and Co KG
Publication of JP2024540480A publication Critical patent/JP2024540480A/ja
Publication of JP2024540480A5 publication Critical patent/JP2024540480A5/ja
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2024529330A 2021-11-17 2022-11-16 腎臓疾患の貧血を処置する方法 Pending JP2024540480A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163280594P 2021-11-17 2021-11-17
US63/280,594 2021-11-17
US202263419648P 2022-10-26 2022-10-26
US63/419,648 2022-10-26
PCT/US2022/079987 WO2023091968A1 (en) 2021-11-17 2022-11-16 Methods for treating anemia of kidney disease

Publications (2)

Publication Number Publication Date
JP2024540480A true JP2024540480A (ja) 2024-10-31
JP2024540480A5 JP2024540480A5 (https=) 2025-11-21

Family

ID=84923162

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024529330A Pending JP2024540480A (ja) 2021-11-17 2022-11-16 腎臓疾患の貧血を処置する方法

Country Status (8)

Country Link
US (1) US20240417458A1 (https=)
EP (1) EP4433160A1 (https=)
JP (1) JP2024540480A (https=)
KR (1) KR20240101681A9 (https=)
AU (1) AU2022394462A1 (https=)
CA (1) CA3235096A1 (https=)
MX (1) MX2024006006A (https=)
WO (1) WO2023091968A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3204283A1 (en) 2011-12-14 2013-06-20 AbbVie Deutschland GmbH & Co. KG Composition and method for the diagnosis and treatment of iron-related disorders
KR20230012539A (ko) 2020-05-13 2023-01-26 디스크 메디슨, 인크. 골수섬유증을 치료하기 위한 항-헤모주벨린 (hjv) 항체

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Also Published As

Publication number Publication date
EP4433160A1 (en) 2024-09-25
CA3235096A1 (en) 2023-05-25
AU2022394462A1 (en) 2024-05-02
US20240417458A1 (en) 2024-12-19
MX2024006006A (es) 2024-08-27
KR20240101681A9 (ko) 2025-12-10
WO2023091968A1 (en) 2023-05-25
KR20240101681A (ko) 2024-07-02

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