JP2024540015A5 - - Google Patents

Info

Publication number
JP2024540015A5
JP2024540015A5 JP2024525058A JP2024525058A JP2024540015A5 JP 2024540015 A5 JP2024540015 A5 JP 2024540015A5 JP 2024525058 A JP2024525058 A JP 2024525058A JP 2024525058 A JP2024525058 A JP 2024525058A JP 2024540015 A5 JP2024540015 A5 JP 2024540015A5
Authority
JP
Japan
Prior art keywords
braf
cancer
inhibitor
raf
use according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024525058A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024540015A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/078771 external-priority patent/WO2023076991A1/en
Publication of JP2024540015A publication Critical patent/JP2024540015A/ja
Publication of JP2024540015A5 publication Critical patent/JP2024540015A5/ja
Pending legal-status Critical Current

Links

JP2024525058A 2021-10-28 2022-10-27 異常な細胞成長を処置するための併用療法 Pending JP2024540015A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163272899P 2021-10-28 2021-10-28
US63/272,899 2021-10-28
PCT/US2022/078771 WO2023076991A1 (en) 2021-10-28 2022-10-27 Combination therapy for treating abnormal cell growth

Publications (2)

Publication Number Publication Date
JP2024540015A JP2024540015A (ja) 2024-10-31
JP2024540015A5 true JP2024540015A5 (https=) 2025-11-05

Family

ID=86158717

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024525058A Pending JP2024540015A (ja) 2021-10-28 2022-10-27 異常な細胞成長を処置するための併用療法

Country Status (10)

Country Link
US (1) US20250009746A1 (https=)
EP (1) EP4422617A4 (https=)
JP (1) JP2024540015A (https=)
KR (1) KR20240095266A (https=)
CN (1) CN118510505A (https=)
AU (1) AU2022376939A1 (https=)
CA (1) CA3235499A1 (https=)
IL (1) IL312248A (https=)
MX (1) MX2024005024A (https=)
WO (1) WO2023076991A1 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021206684B2 (en) 2020-01-10 2024-01-18 Immuneering Corporation MEK inhibitors and therapeutic uses thereof
WO2022047145A1 (en) 2020-08-28 2022-03-03 Arvinas Operations, Inc. Rapidly accelerating fibrosarcoma protein degrading compounds and associated methods of use
US11873296B2 (en) 2022-06-07 2024-01-16 Verastem, Inc. Solid forms of a dual RAF/MEK inhibitor
WO2024054591A1 (en) * 2022-09-07 2024-03-14 Arvinas Operations, Inc. Rapidly accelerated fibrosarcoma (raf) degrading compounds and associated methods of use
TW202517624A (zh) * 2023-07-03 2025-05-01 美商醫療免疫工程公司 Mek免疫腫瘤抑制劑醫藥組合物
CN116570599B (zh) * 2023-07-04 2023-10-20 四川大学华西医院 Vs6766联合ly3009120的应用及药物组合物
US20250049810A1 (en) 2023-08-07 2025-02-13 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder
AU2024360465A1 (en) 2023-10-12 2026-04-09 Revolution Medicines, Inc. Macrocyclic ras inhibitors
WO2025171296A1 (en) 2024-02-09 2025-08-14 Revolution Medicines, Inc. Ras inhibitors
TW202547461A (zh) 2024-05-17 2025-12-16 美商銳新醫藥公司 Ras抑制劑
WO2025255438A1 (en) 2024-06-07 2025-12-11 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder
WO2025265060A1 (en) 2024-06-21 2025-12-26 Revolution Medicines, Inc. Therapeutic compositions and methods for managing treatment-related effects
WO2026006747A1 (en) 2024-06-28 2026-01-02 Revolution Medicines, Inc. Ras inhibitors
WO2026015801A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015790A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015796A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015825A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Use of ras inhibitor for treating pancreatic cancer
WO2026050446A1 (en) 2024-08-29 2026-03-05 Revolution Medicines, Inc. Ras inhibitors
WO2026072904A2 (en) 2024-09-26 2026-04-02 Revolution Medicines, Inc. Compositions and methods for treating lung cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10668055B2 (en) * 2013-12-20 2020-06-02 Biomed Valley Discoveries, Inc. Cancer treatment using combinations of ERK and RAF inhibitors
US20170112865A1 (en) * 2014-05-21 2017-04-27 The Board Of Regents Of The University Of Texas System Treatment for melanoma
JP6864990B2 (ja) * 2015-04-16 2021-04-28 日東電工株式会社 Braf遺伝子変異を有する細胞に対する細胞死誘導剤、当該細胞の増殖抑制剤及び当該細胞の増殖異常に起因する疾患の治療用医薬組成物
KR20200037820A (ko) * 2017-08-07 2020-04-09 에볼 사이언스 엘엘씨 암을 치료하기 위한 조합
JP2022547358A (ja) * 2019-09-13 2022-11-14 ジ インスティテュート オブ キャンサー リサーチ:ロイヤル キャンサー ホスピタル 治療組成物、組み合わせ、及び使用方法

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