JP2024539852A5 - - Google Patents

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Publication number
JP2024539852A5
JP2024539852A5 JP2024521120A JP2024521120A JP2024539852A5 JP 2024539852 A5 JP2024539852 A5 JP 2024539852A5 JP 2024521120 A JP2024521120 A JP 2024521120A JP 2024521120 A JP2024521120 A JP 2024521120A JP 2024539852 A5 JP2024539852 A5 JP 2024539852A5
Authority
JP
Japan
Application number
JP2024521120A
Other languages
Japanese (ja)
Other versions
JP2024539852A (ja
JPWO2023078881A5 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2022/080475 external-priority patent/WO2023078881A1/en
Publication of JP2024539852A publication Critical patent/JP2024539852A/ja
Publication of JP2024539852A5 publication Critical patent/JP2024539852A5/ja
Publication of JPWO2023078881A5 publication Critical patent/JPWO2023078881A5/ja
Pending legal-status Critical Current

Links

JP2024521120A 2021-11-04 2022-11-02 がんの治療のためのキナゾリノン化合物の新規使用 Pending JP2024539852A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21206336 2021-11-04
EP21206336.6 2021-11-04
PCT/EP2022/080475 WO2023078881A1 (en) 2021-11-04 2022-11-02 Novel use of quinazolinone compound for the treatment of cancer

Publications (3)

Publication Number Publication Date
JP2024539852A JP2024539852A (ja) 2024-10-31
JP2024539852A5 true JP2024539852A5 (https=) 2025-11-11
JPWO2023078881A5 JPWO2023078881A5 (https=) 2025-11-11

Family

ID=78516703

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024521120A Pending JP2024539852A (ja) 2021-11-04 2022-11-02 がんの治療のためのキナゾリノン化合物の新規使用

Country Status (11)

Country Link
US (1) US20240366605A1 (https=)
EP (1) EP4426305A1 (https=)
JP (1) JP2024539852A (https=)
KR (1) KR20240105382A (https=)
CN (1) CN118201615A (https=)
AU (1) AU2022383040A1 (https=)
CA (1) CA3230652A1 (https=)
IL (1) IL312171A (https=)
MX (1) MX2024005107A (https=)
TW (1) TW202333707A (https=)
WO (1) WO2023078881A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7834721B2 (ja) 2020-08-28 2026-03-24 アルビナス・オペレーションズ・インコーポレイテッド 急速進行性線維肉腫タンパク質分解化合物及び関連する使用方法
WO2022261250A1 (en) 2021-06-08 2022-12-15 C4 Therapeutics, Inc. Therapeutics for the degradation of mutant braf
EP4584258A1 (en) 2022-09-07 2025-07-16 Arvinas Operations, Inc. Rapidly accelerated fibrosarcoma (raf) degrading compounds and associated methods of use
CN120265291A (zh) * 2022-11-18 2025-07-04 豪夫迈·罗氏有限公司 喹唑啉酮化合物的新用途和制剂
CN120359214A (zh) * 2022-12-15 2025-07-22 豪夫迈·罗氏有限公司 用于癌症治疗的组合疗法
WO2025261943A1 (en) * 2024-06-18 2025-12-26 F. Hoffmann-La Roche Ag Anti-cancer combinations comprising mosperafenib and folfox or folfiri

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG2013013339A (en) 2002-03-13 2014-12-30 Array Biopharma Inc N3 alkylated benzimidazole derivatives as mek inhibitors
HRP20110498T1 (hr) 2005-10-07 2011-08-31 Exelixis Azetidini kao inhibitori mek za liječenje proliferativnih bolesti
JO3517B1 (ar) 2014-01-17 2020-07-05 Novartis Ag ان-ازاسبيرو الكان حلقي كبديل مركبات اريل-ان مغايرة وتركيبات لتثبيط نشاط shp2
CN105899493B (zh) 2014-01-17 2019-03-29 诺华股份有限公司 用于抑制shp2活性的1-(三嗪-3-基/哒嗪-3-基)-哌(-嗪)啶衍生物及其组合物
JP6523303B2 (ja) 2014-01-17 2019-05-29 ノバルティス アーゲー Shp2の活性を阻害するための1−ピリダジン/トリアジン−3−イル−ピペラジン/ピペリジン/ピロリジン誘導体およびその組成物
MX2020003579A (es) 2017-10-12 2020-07-22 Revolution Medicines Inc Compuestos de piridina, pirazina, y triazina como inhibidores de shp2 alostericos.
TWI817018B (zh) * 2019-06-28 2023-10-01 美商艾瑞生藥股份有限公司 用於治療braf相關的疾病和失調症之化合物
PL4073065T3 (pl) 2019-12-10 2025-05-19 F. Hoffmann-La Roche Ag Nowe pochodne metylochinazolinonu
BR112023025916A2 (pt) * 2021-06-09 2024-02-27 Chugai Pharmaceutical Co Ltd Combinação de um inibidor de braf e um inibidor de mek, uso de uma combinação, método para o tratamento ou profilaxia de câncer, composições farmacêuticas e invenção
AU2022289684A1 (en) * 2021-06-09 2023-10-05 F. Hoffmann-La Roche Ag Combination of a particular braf inhibitor (paradox breaker) and a pd-1 axis binding antagonist for use in the treatment of cancer

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