JP2024539655A5 - - Google Patents

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Publication number
JP2024539655A5
JP2024539655A5 JP2024522548A JP2024522548A JP2024539655A5 JP 2024539655 A5 JP2024539655 A5 JP 2024539655A5 JP 2024522548 A JP2024522548 A JP 2024522548A JP 2024522548 A JP2024522548 A JP 2024522548A JP 2024539655 A5 JP2024539655 A5 JP 2024539655A5
Authority
JP
Japan
Prior art keywords
substituted
unsubstituted
hydrogen
unsubstituted alkyl
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024522548A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024539655A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/046386 external-priority patent/WO2023064343A1/en
Publication of JP2024539655A publication Critical patent/JP2024539655A/ja
Publication of JP2024539655A5 publication Critical patent/JP2024539655A5/ja
Pending legal-status Critical Current

Links

JP2024522548A 2021-10-13 2022-10-12 グルコセレブロシダーゼ活性の小分子モジュレーターおよびその使用 Pending JP2024539655A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163255272P 2021-10-13 2021-10-13
US63/255,272 2021-10-13
PCT/US2022/046386 WO2023064343A1 (en) 2021-10-13 2022-10-12 Small molecule modulators of glucocerebrosidase activity and uses thereof

Publications (2)

Publication Number Publication Date
JP2024539655A JP2024539655A (ja) 2024-10-29
JP2024539655A5 true JP2024539655A5 (https=) 2025-10-20

Family

ID=85988704

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024522548A Pending JP2024539655A (ja) 2021-10-13 2022-10-12 グルコセレブロシダーゼ活性の小分子モジュレーターおよびその使用

Country Status (15)

Country Link
US (1) US20250034170A1 (https=)
EP (1) EP4415706A4 (https=)
JP (1) JP2024539655A (https=)
KR (1) KR20240102969A (https=)
CN (1) CN118382436A (https=)
AR (1) AR127355A1 (https=)
AU (1) AU2022364718A1 (https=)
CA (1) CA3235270A1 (https=)
CL (1) CL2024001109A1 (https=)
IL (1) IL312086A (https=)
JO (1) JOP20240081A1 (https=)
MX (1) MX2024004581A (https=)
PE (1) PE20242105A1 (https=)
TW (1) TW202327586A (https=)
WO (1) WO2023064343A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN121941686A (zh) * 2023-10-04 2026-04-28 美利坚合众国,由健康及人类服务部部长代表 用于治疗神经退行性疾病的融合杂环
WO2025237303A1 (zh) * 2024-05-14 2025-11-20 先声药业有限公司 β-葡萄糖脑苷脂酶变构调节剂、其药物组合物及用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0302811D0 (sv) * 2003-10-23 2003-10-23 Astrazeneca Ab Novel compounds
DE102005030051A1 (de) * 2005-06-27 2006-12-28 Grünenthal GmbH Substituierte 1-Oxa-3,8-diazaspiro[4,5]-decan-2-on-Verbindungen und deren Verwendung zur Herstellung von Arzneimitteln
GB0601402D0 (en) * 2006-01-24 2006-03-08 Syngenta Participations Ag Chemical Compounds
MX2009002920A (es) * 2006-09-15 2009-04-01 Schering Corp Tratamiento del dolor, diabetes y trastornos del metabolismo de los lipidos.
TW201026708A (en) * 2008-12-12 2010-07-16 Solvay Pharm Bv Spiro azepane-oxazolidinones as Kv1.3 potassium channel blockers
CN103517910B (zh) * 2011-03-14 2016-12-14 沃泰克斯药物股份有限公司 作为离子通道调节剂的吗啉-螺环哌啶酰胺
US9796680B2 (en) * 2013-12-23 2017-10-24 Alectos Therapeutics Inc. Glucocerebrosidase modulators and uses thereof

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