JP2024535852A5 - - Google Patents

Info

Publication number
JP2024535852A5
JP2024535852A5 JP2024516862A JP2024516862A JP2024535852A5 JP 2024535852 A5 JP2024535852 A5 JP 2024535852A5 JP 2024516862 A JP2024516862 A JP 2024516862A JP 2024516862 A JP2024516862 A JP 2024516862A JP 2024535852 A5 JP2024535852 A5 JP 2024535852A5
Authority
JP
Japan
Prior art keywords
dsrna agent
angptl4
subject
nucleotides
disorder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024516862A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024535852A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/076613 external-priority patent/WO2023044458A1/en
Publication of JP2024535852A publication Critical patent/JP2024535852A/ja
Publication of JP2024535852A5 publication Critical patent/JP2024535852A5/ja
Pending legal-status Critical Current

Links

JP2024516862A 2021-09-17 2022-09-16 ＡＮＧＰＴＬ４をサイレンシングするためのｉＲＮＡ組成物および方法 Pending JP2024535852A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163245693P 2021-09-17 2021-09-17
US63/245,693 2021-09-17
US202263317480P 2022-03-07 2022-03-07
US63/317,480 2022-03-07
PCT/US2022/076613 WO2023044458A1 (en) 2021-09-17 2022-09-16 Irna compositions and methods for silencing angptl4

Publications (2)

Publication Number Publication Date
JP2024535852A JP2024535852A (ja) 2024-10-02
JP2024535852A5 true JP2024535852A5 (enExample) 2025-11-06

Family

ID=85603655

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024516862A Pending JP2024535852A (ja) 2021-09-17 2022-09-16 ＡＮＧＰＴＬ４をサイレンシングするためのｉＲＮＡ組成物および方法

Country Status (4)

Country Link
US (1) US20250136978A1 (enExample)
EP (1) EP4402261A4 (enExample)
JP (1) JP2024535852A (enExample)
WO (1) WO2023044458A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023239307A1 (en) * 2022-06-10 2023-12-14 Nanyang Technological University Methods of treating liver fibrosis, inflammation or associated diseases using an angptl4 antagonist
CN120019148A (zh) * 2023-08-22 2025-05-16 成都先衍生物技术有限公司 一种靶向ANGPTL4的siRNA及其缀合物和用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030194704A1 (en) * 2002-04-03 2003-10-16 Penn Sharron Gaynor Human genome-derived single exon nucleic acid probes useful for gene expression analysis two
BRPI0606432A2 (pt) * 2005-01-07 2009-06-30 Lexicon Pharmaceuticals Inc anticorpos monoclonais contra angptl4
BR112017021053A2 (en) * 2015-04-13 2018-08-14 Alnylam Pharmaceuticals, Inc. angiopoietin type 3 (angpt13) irna compositions and methods of use thereof
CA3029121A1 (en) * 2016-06-29 2018-01-04 Crispr Therapeutics Ag Compositions and methods for gene editing
CA3164050A1 (en) * 2019-12-09 2021-06-17 Empirico Inc. Oligonucleotides for treatment of angiopoietin like 4 (angptl4) related diseases

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