JP2024535637A5 - - Google Patents
Info
- Publication number
- JP2024535637A5 JP2024535637A5 JP2024542231A JP2024542231A JP2024535637A5 JP 2024535637 A5 JP2024535637 A5 JP 2024535637A5 JP 2024542231 A JP2024542231 A JP 2024542231A JP 2024542231 A JP2024542231 A JP 2024542231A JP 2024535637 A5 JP2024535637 A5 JP 2024535637A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid sequence
- chain variable
- variable region
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111139621.4 | 2021-09-27 | ||
| CN202111139621 | 2021-09-27 | ||
| CN202210915323.8 | 2022-08-01 | ||
| CN202210915323 | 2022-08-01 | ||
| PCT/CN2022/121776 WO2023046202A1 (zh) | 2021-09-27 | 2022-09-27 | 一种抗体及其药物偶联物和用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024535637A JP2024535637A (ja) | 2024-09-30 |
| JP2024535637A5 true JP2024535637A5 (enExample) | 2026-02-18 |
Family
ID=85720158
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024542231A Pending JP2024535637A (ja) | 2021-09-27 | 2022-09-27 | 抗体及びその薬物コンジュゲ－ト並びに用途 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20240409628A1 (enExample) |
| EP (1) | EP4410372A4 (enExample) |
| JP (1) | JP2024535637A (enExample) |
| KR (1) | KR20240082348A (enExample) |
| CN (3) | CN122302064A (enExample) |
| AU (1) | AU2022350588A1 (enExample) |
| CA (1) | CA3233254A1 (enExample) |
| WO (1) | WO2023046202A1 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2023389998A1 (en) * | 2022-12-07 | 2025-06-12 | Merck Sharp & Dohme Llc | Process for making antibody-drug conjugates |
| KR20260007619A (ko) * | 2023-05-09 | 2026-01-14 | 상하이 헨리우스 바이오테크, 인크. | 항-pdl1 항체-약물 접합체 및 응용 |
| CN121263211A (zh) * | 2023-05-09 | 2026-01-02 | 上海复宏汉霖生物技术股份有限公司 | 一种抗表皮生长因子受体(egfr)抗体-药物偶联物及其应用 |
| JP7689606B2 (ja) * | 2023-06-20 | 2025-06-06 | イーライ リリー アンド カンパニー | ネクチン－４抗体及び抗体－薬物コンジュゲート |
| CN121889155A (zh) | 2023-08-07 | 2026-04-17 | 锐新医药公司 | 用于治疗ras蛋白相关疾病或病症的rmc-6291 |
| AU2024360465A1 (en) | 2023-10-12 | 2026-04-09 | Revolution Medicines, Inc. | Macrocyclic ras inhibitors |
| TW202539743A (zh) * | 2024-02-07 | 2025-10-16 | 大陸商長春金賽藥業有限責任公司 | 帶有連接系統的抗體藥物偶聯物 |
| WO2025171296A1 (en) | 2024-02-09 | 2025-08-14 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025240847A1 (en) | 2024-05-17 | 2025-11-20 | Revolution Medicines, Inc. | Ras inhibitors |
| TW202547557A (zh) * | 2024-05-30 | 2025-12-16 | 德商拜恩技術股份公司 | 抗體藥物結合物之新用途 |
| US20250375445A1 (en) | 2024-06-07 | 2025-12-11 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| WO2025265060A1 (en) | 2024-06-21 | 2025-12-26 | Revolution Medicines, Inc. | Therapeutic compositions and methods for managing treatment-related effects |
| WO2026006747A1 (en) | 2024-06-28 | 2026-01-02 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026015825A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Use of ras inhibitor for treating pancreatic cancer |
| WO2026015796A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015801A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015790A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026050446A1 (en) | 2024-08-29 | 2026-03-05 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026072904A2 (en) | 2024-09-26 | 2026-04-02 | Revolution Medicines, Inc. | Compositions and methods for treating lung cancer |
| WO2026090116A2 (en) | 2024-10-21 | 2026-04-30 | Revolution Medicines, Inc. | Ras inhibitors |
| US20260108528A1 (en) | 2024-10-22 | 2026-04-23 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| WO2026090245A1 (en) | 2024-10-22 | 2026-04-30 | Revolution Medicines, Inc. | Use of ras inhibitors for treating cancer |
| WO2026085745A1 (en) * | 2024-10-23 | 2026-04-30 | Zai Lab (Shanghai) Co., Ltd. | Dosing regimens of antibody-drug conjugate targeting delta-like ligand 3 for treatment of neuroendocrine neoplasms |
| WO2026086850A1 (en) * | 2024-10-23 | 2026-04-30 | Zai Lab (Shanghai) Co., Ltd. | Dosing regimens of antibody-drug conjugate targeting delta-like ligand 3 for treatment of neuroendocrine neoplasms |
| CN119345386B (zh) * | 2024-10-25 | 2025-12-09 | 华润生物医药有限公司 | 靶向Claudin18.2的抗体药物耦联物及其用途 |
| WO2026106912A1 (en) | 2024-11-12 | 2026-05-21 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026112260A1 (en) | 2024-11-21 | 2026-05-28 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026122764A2 (en) | 2024-12-06 | 2026-06-11 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026128688A2 (en) | 2024-12-13 | 2026-06-18 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026161839A1 (en) | 2025-01-27 | 2026-07-30 | Revolution Medicines, Inc. | Ras inhibitors |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1790664A1 (en) | 2005-11-24 | 2007-05-30 | Ganymed Pharmaceuticals AG | Monoclonal antibodies against claudin-18 for treatment of cancer |
| CN111936169A (zh) | 2018-04-06 | 2020-11-13 | 西雅图遗传学公司 | 喜树碱肽缀合物 |
| TWI920652B (zh) * | 2018-06-07 | 2026-04-01 | 美商思進公司 | 喜樹鹼結合物 |
| CN111110862A (zh) * | 2018-11-01 | 2020-05-08 | 上海健信生物医药科技有限公司 | 抗cldn18．2抗体的药物偶联体及其制备方法和用途 |
| EP3808376A4 (en) * | 2018-06-17 | 2021-09-01 | L&L Biopharma Co., Ltd. | CLDN18.2 ANTIBODY, BISPECIFIC ANTIBODY, ADC AND CAR, AND APPLICATIONS THEREOF |
| CN110862454B (zh) * | 2018-08-27 | 2022-12-30 | 南京圣和药业股份有限公司 | 一种抗Claudin18_2抗体及其应用 |
| CN111433188B (zh) * | 2018-12-17 | 2023-08-01 | 荣昌生物制药(烟台)股份有限公司 | 一种用于抗体药物偶联物的连接子及其应用 |
| CN109762067B (zh) * | 2019-01-17 | 2020-02-28 | 北京天广实生物技术股份有限公司 | 结合人Claudin 18.2的抗体及其用途 |
| BR112021023024A2 (pt) * | 2019-05-16 | 2022-01-25 | Qilu Pharmaceutical Co Ltd | Anticorpo contra claudina 18a2 e uso do mesmo |
| WO2020259258A1 (zh) * | 2019-06-28 | 2020-12-30 | 上海复旦张江生物医药股份有限公司 | 一种抗体偶联药物、其中间体、制备方法及应用 |
| CN112237634B (zh) * | 2019-07-19 | 2023-11-28 | 上海复旦张江生物医药股份有限公司 | 抗体药物偶联物、其中间体、制备方法及应用 |
| CN120093941A (zh) | 2021-02-09 | 2025-06-06 | 苏州宜联生物医药有限公司 | 生物活性物偶联物及其制备方法和用途 |
-
2022
- 2022-09-27 CA CA3233254A patent/CA3233254A1/en active Pending
- 2022-09-27 CN CN202610640633.1A patent/CN122302064A/zh active Pending
- 2022-09-27 EP EP22872245.0A patent/EP4410372A4/en active Pending
- 2022-09-27 US US18/695,296 patent/US20240409628A1/en active Pending
- 2022-09-27 WO PCT/CN2022/121776 patent/WO2023046202A1/zh not_active Ceased
- 2022-09-27 KR KR1020247011648A patent/KR20240082348A/ko active Pending
- 2022-09-27 JP JP2024542231A patent/JP2024535637A/ja active Pending
- 2022-09-27 CN CN202280065004.0A patent/CN118159300B/zh active Active
- 2022-09-27 CN CN202610640640.1A patent/CN122321167A/zh active Pending
- 2022-09-27 AU AU2022350588A patent/AU2022350588A1/en active Pending
-
2026
- 2026-03-24 US US19/577,068 patent/US20260201030A1/en active Pending
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