JP2024531431A5 - - Google Patents

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Publication number
JP2024531431A5
JP2024531431A5 JP2024510636A JP2024510636A JP2024531431A5 JP 2024531431 A5 JP2024531431 A5 JP 2024531431A5 JP 2024510636 A JP2024510636 A JP 2024510636A JP 2024510636 A JP2024510636 A JP 2024510636A JP 2024531431 A5 JP2024531431 A5 JP 2024531431A5
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JP
Japan
Prior art keywords
gene
nln
library
eukaryotic cell
cell
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Pending
Application number
JP2024510636A
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English (en)
Japanese (ja)
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JP2024531431A (ja
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Application filed filed Critical
Priority claimed from PCT/EP2022/073549 external-priority patent/WO2023025834A1/en
Publication of JP2024531431A publication Critical patent/JP2024531431A/ja
Publication of JP2024531431A5 publication Critical patent/JP2024531431A5/ja
Pending legal-status Critical Current

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JP2024510636A 2021-08-25 2022-08-24 真核細胞で発現するタンパク質変異体のライブラリーの調製 Pending JP2024531431A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21193102 2021-08-25
EP21193102.7 2021-08-25
PCT/EP2022/073549 WO2023025834A1 (en) 2021-08-25 2022-08-24 Preparation of libraries of protein variants expressed in eukaryotic cells

Publications (2)

Publication Number Publication Date
JP2024531431A JP2024531431A (ja) 2024-08-29
JP2024531431A5 true JP2024531431A5 (https=) 2025-08-26

Family

ID=77774665

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024510636A Pending JP2024531431A (ja) 2021-08-25 2022-08-24 真核細胞で発現するタンパク質変異体のライブラリーの調製

Country Status (7)

Country Link
US (1) US20250129362A1 (https=)
EP (1) EP4392571A1 (https=)
JP (1) JP2024531431A (https=)
CN (1) CN118525099A (https=)
AU (1) AU2022334794A1 (https=)
CA (1) CA3229003A1 (https=)
WO (1) WO2023025834A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024251820A1 (en) 2023-06-06 2024-12-12 Iontas Limited Preparation of libraries of bispecific binders expressed in eukaryotic cells

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61134325A (ja) 1984-12-04 1986-06-21 Teijin Ltd ハイブリツド抗体遺伝子の発現方法
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
ES2156149T3 (es) 1992-12-04 2001-06-16 Medical Res Council Proteinas de union multivalente y multiespecificas, su fabricacion y su uso.
DK1137941T4 (da) 1998-12-10 2014-01-06 Brystol Myers Squibb Company Protein-scaffolds til antistof-mimetika og andre bindingsproteiner
CA2789446A1 (en) 2010-02-12 2011-08-18 Oncomed Pharmaceuticals, Inc. Methods for identifying and isolating cells expressing a polypeptide
AU2012249390B2 (en) 2011-04-27 2017-03-30 Amyris, Inc. Methods for genomic modification
BR112015031639A2 (pt) * 2013-06-19 2019-09-03 Sigma Aldrich Co Llc integração alvo
US9209965B2 (en) 2014-01-14 2015-12-08 Microsemi Semiconductor Ulc Network interface with clock recovery module on line card
GB201407852D0 (en) 2014-05-02 2014-06-18 Iontas Ltd Preparation of libraries od protein variants expressed in eukaryotic cells and use for selecting binding molecules
US11293033B2 (en) * 2016-05-18 2022-04-05 Amyris, Inc. Compositions and methods for genomic integration of nucleic acids into exogenous landing pads
GB201720351D0 (en) 2017-12-06 2018-01-17 Iontas Ltd Selecting for developability in drug discovery
IL275462B2 (en) * 2017-12-22 2026-01-01 Genentech Inc Targeted integration of nucleic acids

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