CN118525099A - 真核细胞中表达的蛋白质变体文库的制备 - Google Patents
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- C12N15/1082—Preparation or screening gene libraries by chromosomal integration of polynucleotide sequences, HR-, site-specific-recombination, transposons, viral vectors
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- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
- C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
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| EP21193102 | 2021-08-25 | ||
| EP21193102.7 | 2021-08-25 | ||
| PCT/EP2022/073549 WO2023025834A1 (en) | 2021-08-25 | 2022-08-24 | Preparation of libraries of protein variants expressed in eukaryotic cells |
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| US11293033B2 (en) * | 2016-05-18 | 2022-04-05 | Amyris, Inc. | Compositions and methods for genomic integration of nucleic acids into exogenous landing pads |
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| IL275462B2 (en) * | 2017-12-22 | 2026-01-01 | Genentech Inc | Targeted integration of nucleic acids |
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