JP2024531346A5 - - Google Patents

Info

Publication number
JP2024531346A5
JP2024531346A5 JP2024509419A JP2024509419A JP2024531346A5 JP 2024531346 A5 JP2024531346 A5 JP 2024531346A5 JP 2024509419 A JP2024509419 A JP 2024509419A JP 2024509419 A JP2024509419 A JP 2024509419A JP 2024531346 A5 JP2024531346 A5 JP 2024531346A5
Authority
JP
Japan
Prior art keywords
amino acid
seq
substitution
residue
acid residue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024509419A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024531346A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2022/073145 external-priority patent/WO2023021169A1/en
Publication of JP2024531346A publication Critical patent/JP2024531346A/ja
Publication of JP2024531346A5 publication Critical patent/JP2024531346A5/ja
Pending legal-status Critical Current

Links

JP2024509419A 2021-08-20 2022-08-19 半減期が延長された抗体およびIgG融合タンパク質 Pending JP2024531346A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163235259P 2021-08-20 2021-08-20
US202163235261P 2021-08-20 2021-08-20
US63/235,261 2021-08-20
US63/235,259 2021-08-20
US202263341443P 2022-05-13 2022-05-13
US63/341,443 2022-05-13
PCT/EP2022/073145 WO2023021169A1 (en) 2021-08-20 2022-08-19 Antibodies and igg fusion proteins with an extended half-life

Publications (2)

Publication Number Publication Date
JP2024531346A JP2024531346A (ja) 2024-08-29
JP2024531346A5 true JP2024531346A5 (https=) 2025-08-22

Family

ID=83280226

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024509419A Pending JP2024531346A (ja) 2021-08-20 2022-08-19 半減期が延長された抗体およびIgG融合タンパク質

Country Status (7)

Country Link
US (1) US20250197514A1 (https=)
EP (1) EP4388004A1 (https=)
JP (1) JP2024531346A (https=)
AU (1) AU2022329459A1 (https=)
CA (1) CA3227716A1 (https=)
MX (1) MX2024002150A (https=)
WO (1) WO2023021169A1 (https=)

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US4447224A (en) 1982-09-20 1984-05-08 Infusaid Corporation Variable flow implantable infusion apparatus
US4487603A (en) 1982-11-26 1984-12-11 Cordis Corporation Implantable microinfusion pump system
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4596556A (en) 1985-03-25 1986-06-24 Bioject, Inc. Hypodermic injection apparatus
EP0216846B2 (en) 1985-04-01 1995-04-26 Celltech Limited Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same
GB8601597D0 (en) 1986-01-23 1986-02-26 Wilson R H Nucleotide sequences
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US4941880A (en) 1987-06-19 1990-07-17 Bioject, Inc. Pre-filled ampule and non-invasive hypodermic injection device assembly
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US7217797B2 (en) 2002-10-15 2007-05-15 Pdl Biopharma, Inc. Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
WO2005037867A1 (en) 2003-10-15 2005-04-28 Pdl Biopharma, Inc. ALTERATION OF Fc-FUSION PROTEIN SERUM HALF-LIVES BY MUTAGENESIS OF POSITIONS 250, 314 AND/OR 428 OF THE HEAVY CHAIN CONSTANT REGION OF IG
US8367805B2 (en) 2004-11-12 2013-02-05 Xencor, Inc. Fc variants with altered binding to FcRn
CN106029697B (zh) 2013-12-20 2021-06-04 英特维特国际股份有限公司 具有经修饰的ch2-ch3序列的犬抗体
US20200181258A1 (en) 2016-10-17 2020-06-11 Vetoquinol Sa Modified antibody constant region
IL276286B2 (en) 2018-01-26 2025-07-01 Genzyme Corp FC variants with improved binding to FCRN and extended half-life
US20210388053A1 (en) 2018-10-18 2021-12-16 Kindred Biosciences, Inc. Fc Variants with Altered Binding to Neonatal Fc Receptor (FCRN) for Veterinary Use
JP7536294B2 (ja) * 2018-12-05 2024-08-20 株式会社バイカ・セラピュティクス 抗体のFc領域改変体
CN113544153B (zh) 2019-01-03 2024-12-10 因外泰克斯公司 用于增加治疗剂在犬中的半衰期的组合物及使用方法
US20220169740A1 (en) 2019-03-20 2022-06-02 Kindred Biosciences, Inc. NGF Antagonists for Medical Use
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CN120590527A (zh) 2020-05-11 2025-09-05 因外泰克斯公司 用于增加治疗剂在犬中的半衰期的组合物和使用方法

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