JP2024526939A - 酸化的網膜疾患の進行を抑制する方法 - Google Patents

酸化的網膜疾患の進行を抑制する方法 Download PDF

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Publication number
JP2024526939A
JP2024526939A JP2024503840A JP2024503840A JP2024526939A JP 2024526939 A JP2024526939 A JP 2024526939A JP 2024503840 A JP2024503840 A JP 2024503840A JP 2024503840 A JP2024503840 A JP 2024503840A JP 2024526939 A JP2024526939 A JP 2024526939A
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JP2024526939A5 (enExample
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シュミット カルステン
シチェピノフ ミハイル
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バイオジーバ リミティド ライアビリティ カンパニー
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Publication of JP2024526939A5 publication Critical patent/JP2024526939A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2024503840A 2021-07-22 2022-07-22 酸化的網膜疾患の進行を抑制する方法 Pending JP2024526939A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163224690P 2021-07-22 2021-07-22
US202163224674P 2021-07-22 2021-07-22
US202163224679P 2021-07-22 2021-07-22
US63/224,679 2021-07-22
US63/224,674 2021-07-22
US63/224,690 2021-07-22
PCT/US2022/038072 WO2023004151A1 (en) 2021-07-22 2022-07-22 Methods for inhibiting the progression of oxidative retinal diseases

Publications (2)

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JP2024526939A true JP2024526939A (ja) 2024-07-19
JP2024526939A5 JP2024526939A5 (enExample) 2024-07-29

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JP2024503840A Pending JP2024526939A (ja) 2021-07-22 2022-07-22 酸化的網膜疾患の進行を抑制する方法

Country Status (8)

Country Link
US (1) US20250099415A1 (enExample)
EP (1) EP4373479A4 (enExample)
JP (1) JP2024526939A (enExample)
KR (1) KR20240036651A (enExample)
AU (1) AU2022313207A1 (enExample)
CA (1) CA3227139A1 (enExample)
IL (1) IL310210A (enExample)
WO (1) WO2023004151A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024049497A1 (en) * 2022-09-02 2024-03-07 Biojiva Llc Pharmaceutical compositions of d10-docosahexaenoic acid or esters thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014514328A (ja) * 2011-04-26 2014-06-19 レトロトップ、 インコーポレイテッド 酸化的網膜疾患
JP2019501135A (ja) * 2015-11-23 2019-01-17 レトロトップ、 インコーポレイテッドＲｅｔｒｏｔｏｐｅ， Ｉｎｃ． １，４−ジエン系の部位特異的同位体標識

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060270739A1 (en) * 2005-04-28 2006-11-30 Trustees Of Tufts College Synergistic effects of docosahexaenoic acid (DHA) and carotenoid absorption on macular pigmentation
WO2009018333A2 (en) * 2007-07-30 2009-02-05 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Dha and pedf, a therapeutic composition for nerve and retinal pigment epithelial cells
US20100324138A1 (en) * 2007-10-29 2010-12-23 Bazan Nicolas G Lipoxin A4 Protection for Retinal Cells
EP3880194A4 (en) * 2018-11-15 2022-11-09 Retrotope, Inc. DEUTERED COMPOUNDS, COMPOSITIONS AND USES

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014514328A (ja) * 2011-04-26 2014-06-19 レトロトップ、 インコーポレイテッド 酸化的網膜疾患
JP2019501135A (ja) * 2015-11-23 2019-01-17 レトロトップ、 インコーポレイテッドＲｅｔｒｏｔｏｐｅ， Ｉｎｃ． １，４−ジエン系の部位特異的同位体標識

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DENNIS R. HOFFMAN, ET AL.: ""Docosahexaenoic Acid Slows Visual Field Progression in X-Linked Retinitis Pigmentosa: Ancillary Out", INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, vol. 56, no. 11, JPN6025039316, 2015, pages 6646 - 6653, ISSN: 0005698257 *
MELISSA ROSELL, ET AL.: "Bis-allylic Deuterated DHA Alleviates Oxidative Stress in Retinal Epithelial Cells"", ANTIOXIDANTS, vol. 8, no. 10, JPN6025039315, 2019, pages 447, ISSN: 0005698256 *

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Publication number Publication date
IL310210A (en) 2024-03-01
CA3227139A1 (en) 2023-01-26
EP4373479A1 (en) 2024-05-29
AU2022313207A1 (en) 2024-02-29
US20250099415A1 (en) 2025-03-27
WO2023004151A1 (en) 2023-01-26
EP4373479A4 (en) 2025-11-05
KR20240036651A (ko) 2024-03-20

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