JP2024526293A - 淋菌を標的とするワクチン - Google Patents

淋菌を標的とするワクチン Download PDF

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Publication number
JP2024526293A
JP2024526293A JP2024500094A JP2024500094A JP2024526293A JP 2024526293 A JP2024526293 A JP 2024526293A JP 2024500094 A JP2024500094 A JP 2024500094A JP 2024500094 A JP2024500094 A JP 2024500094A JP 2024526293 A JP2024526293 A JP 2024526293A
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JP
Japan
Prior art keywords
exactly
amino acid
polypeptide
seq
acid residues
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JP2024500094A
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English (en)
Japanese (ja)
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JP2024526293A5 (enExample
Inventor
ホルム マットソン，アンドレアス
スクト ステーンマンス，クリスチャン
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Evaxion AS
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Evaxion AS
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Publication of JP2024526293A publication Critical patent/JP2024526293A/ja
Publication of JP2024526293A5 publication Critical patent/JP2024526293A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2024500094A 2021-07-05 2022-07-05 淋菌を標的とするワクチン Pending JP2024526293A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21183614 2021-07-05
EP21183614.3 2021-07-05
PCT/EP2022/068509 WO2023280807A1 (en) 2021-07-05 2022-07-05 Vaccines targeting neisseria gonorrhoeae

Publications (2)

Publication Number Publication Date
JP2024526293A true JP2024526293A (ja) 2024-07-17
JP2024526293A5 JP2024526293A5 (enExample) 2025-07-14

Family

ID=77050766

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024500094A Pending JP2024526293A (ja) 2021-07-05 2022-07-05 淋菌を標的とするワクチン

Country Status (7)

Country Link
US (1) US20240424079A1 (enExample)
EP (1) EP4366762A1 (enExample)
JP (1) JP2024526293A (enExample)
CN (1) CN117915944A (enExample)
AU (1) AU2022307747A1 (enExample)
CA (1) CA3224564A1 (enExample)
WO (1) WO2023280807A1 (enExample)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003500420A (ja) * 1999-05-19 2003-01-07 カイロン エセ．ピー．アー． Ｎｅｉｓｓｅｒｉａ配合組成物
JP2004537977A (ja) * 2001-02-12 2004-12-24 カイロン ソチエタ ア レスポンサビリタ リミタータ 淋菌性タンパク質および淋菌性核酸
WO2021022001A1 (en) * 2019-08-01 2021-02-04 Trustees Of Tufts College Vaccine compositions and methods of selecting antigens

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Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003500420A (ja) * 1999-05-19 2003-01-07 カイロン エセ．ピー．アー． Ｎｅｉｓｓｅｒｉａ配合組成物
JP2004537977A (ja) * 2001-02-12 2004-12-24 カイロン ソチエタ ア レスポンサビリタ リミタータ 淋菌性タンパク質および淋菌性核酸
WO2021022001A1 (en) * 2019-08-01 2021-02-04 Trustees Of Tufts College Vaccine compositions and methods of selecting antigens

Also Published As

Publication number Publication date
AU2022307747A9 (en) 2024-02-22
AU2022307747A1 (en) 2024-01-25
WO2023280807A1 (en) 2023-01-12
CA3224564A1 (en) 2023-01-12
US20240424079A1 (en) 2024-12-26
CN117915944A (zh) 2024-04-19
EP4366762A1 (en) 2024-05-15

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