JP2024523702A5 - - Google Patents
Info
- Publication number
- JP2024523702A5 JP2024523702A5 JP2024500176A JP2024500176A JP2024523702A5 JP 2024523702 A5 JP2024523702 A5 JP 2024523702A5 JP 2024500176 A JP2024500176 A JP 2024500176A JP 2024500176 A JP2024500176 A JP 2024500176A JP 2024523702 A5 JP2024523702 A5 JP 2024523702A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- seq
- nucleotide sequence
- nucleotide
- sisod1
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2021105081 | 2021-07-07 | ||
| CNPCT/CN2021/105081 | 2021-07-07 | ||
| CNPCT/CN2022/091076 | 2022-05-06 | ||
| CN2022091076 | 2022-05-06 | ||
| PCT/CN2022/104037 WO2023280190A1 (en) | 2021-07-07 | 2022-07-06 | Oligonucleotide-based delivery vehicle for oligonucleotides agents and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024523702A JP2024523702A (ja) | 2024-06-28 |
| JP2024523702A5 true JP2024523702A5 (https=) | 2025-07-10 |
Family
ID=84801315
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024500176A Pending JP2024523702A (ja) | 2021-07-07 | 2022-07-06 | オリゴヌクレオチド剤用オリゴヌクレオチドベースの送達担体およびその使用方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20250297258A1 (https=) |
| EP (1) | EP4367244A4 (https=) |
| JP (1) | JP2024523702A (https=) |
| KR (1) | KR20240043822A (https=) |
| CN (1) | CN117916374A (https=) |
| AU (1) | AU2022308123A1 (https=) |
| CA (1) | CA3225998A1 (https=) |
| TW (1) | TW202321449A (https=) |
| WO (1) | WO2023280190A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2025522433A (ja) | 2022-06-15 | 2025-07-15 | アローヘッド ファーマシューティカルズ インコーポレイテッド | スーパーオキシドジスムターゼ１（ＳＯＤ１）の発現を阻害するためのＲＮＡｉ剤、その組成物、及び使用の方法 |
| KR20250148653A (ko) * | 2023-02-17 | 2025-10-14 | 아이오니스 파마수티컬즈, 인코포레이티드 | App 발현을 감소시키기 위한 화합물 및 방법 |
| KR20250155023A (ko) * | 2023-02-24 | 2025-10-29 | 락티젠 세러퓨틱스 | Sod1을 표적으로 하는 올리고뉴클레오타이드 |
| WO2024199445A1 (en) * | 2023-03-30 | 2024-10-03 | Ractigen Therapeutics | Vehicles for delivering oligonucleotides and methods of use thereof |
| EP4728073A1 (en) * | 2023-06-16 | 2026-04-22 | Ractigen Therapeutics | Oligonucleotide formulation |
| CN117402096A (zh) * | 2023-10-20 | 2024-01-16 | 康羽生命科学技术(苏州)有限公司 | 一种辅氨酸衍生物的合成方法 |
| WO2025119303A1 (en) * | 2023-12-07 | 2025-06-12 | Ractigen Therapeutics | Abasic modification compound, gene modulating agents and the use thereof |
| WO2025126153A2 (en) * | 2023-12-14 | 2025-06-19 | Aviadobio Ltd. | Compositions and methods for treating sod1-mediated neurological diseases |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2715289C (en) * | 2008-02-11 | 2019-12-24 | Rxi Pharmaceuticals Corporation | Modified rnai polynucleotides and uses thereof |
| EP2342340A1 (en) * | 2008-09-22 | 2011-07-13 | Rxi Pharmaceuticals Corporation | Rna interference in skin indications |
| EP2362729A1 (en) * | 2008-11-17 | 2011-09-07 | Enzon Pharmaceuticals, Inc. | Releasable conjugates for nucleic acids delivery systems |
| US9745574B2 (en) * | 2009-02-04 | 2017-08-29 | Rxi Pharmaceuticals Corporation | RNA duplexes with single stranded phosphorothioate nucleotide regions for additional functionality |
| EP2756845B1 (en) * | 2009-04-03 | 2017-03-15 | Dicerna Pharmaceuticals, Inc. | Methods and compositions for the specific inhibition of KRAS by asymmetric double-stranded RNA |
| RU2615143C2 (ru) * | 2010-03-24 | 2017-04-04 | Адвирна | Самодоставляющие PHKi соединения уменьшенного размера |
| CA2871089A1 (en) * | 2011-04-20 | 2012-10-26 | Smith Holdings, Llc | Methods and compositions for modulating gene expression using components that self assemble in cells and produce rnai activity |
| EP3004347B1 (en) * | 2013-05-30 | 2018-09-26 | National University Corporation Tokyo Medical and Dental University | Double-stranded agents for delivering therapeutic oligonucleotides |
| EP3862005A1 (en) * | 2015-07-06 | 2021-08-11 | Phio Pharmaceuticals Corp. | Nucleic acid molecules targeting superoxide dismutase 1 (sod1) |
| US11260134B2 (en) * | 2016-09-29 | 2022-03-01 | National University Corporation Tokyo Medical And Dental University | Double-stranded nucleic acid complex having overhang |
| SG10201609048RA (en) * | 2016-10-28 | 2018-05-30 | Agency Science Tech & Res | Antisense oligonucleotides |
| US20210002640A1 (en) * | 2018-02-28 | 2021-01-07 | Exicure, Inc. | Liposomal spherical nucleic acid (sna) constructs for survival of motor neuron (sma) inhibitors |
| CN113614232A (zh) * | 2019-01-18 | 2021-11-05 | 马萨诸塞大学 | 动态药代动力学修饰锚 |
-
2022
- 2022-04-18 US US18/577,092 patent/US20250297258A1/en active Pending
- 2022-07-06 CN CN202280048479.9A patent/CN117916374A/zh active Pending
- 2022-07-06 AU AU2022308123A patent/AU2022308123A1/en active Pending
- 2022-07-06 KR KR1020247004696A patent/KR20240043822A/ko active Pending
- 2022-07-06 CA CA3225998A patent/CA3225998A1/en active Pending
- 2022-07-06 WO PCT/CN2022/104037 patent/WO2023280190A1/en not_active Ceased
- 2022-07-06 EP EP22836938.5A patent/EP4367244A4/en active Pending
- 2022-07-06 JP JP2024500176A patent/JP2024523702A/ja active Pending
- 2022-07-06 TW TW111125375A patent/TW202321449A/zh unknown
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