JP2024522148A - インターフェロン誘導ヘリカーゼｃドメイン１（ｉｆｉｈ１）阻害剤による乾癬の治療 - Google Patents

インターフェロン誘導ヘリカーゼｃドメイン１（ｉｆｉｈ１）阻害剤による乾癬の治療 Download PDF

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JP2024522148A
JP2024522148A JP2023574638A JP2023574638A JP2024522148A JP 2024522148 A JP2024522148 A JP 2024522148A JP 2023574638 A JP2023574638 A JP 2023574638A JP 2023574638 A JP2023574638 A JP 2023574638A JP 2024522148 A JP2024522148 A JP 2024522148A
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nucleic acid
ifih1
acid molecule
subject
trim65
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JP2024522148A5 (https=
Inventor
イー． ホロウィッツ、ジュリー
アレン レベズ フェレイラ、マヌエル
シミノビッチ、キャサリン
バラス、アリス
クリミアン、ロリ
カラリス、カティア
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Regeneron Pharmaceuticals Inc
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Regeneron Pharmaceuticals Inc
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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    • A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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    • C12Y306/04—Hydrolases acting on acid anhydrides (3.6) acting on acid anhydrides; involved in cellular and subcellular movement (3.6.4)
    • C12Y306/04013—RNA helicase (3.6.4.13)
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    • C12N2310/50—Physical structure
    • C12N2310/53—Physical structure partially self-complementary or closed
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JP2023574638A 2021-06-10 2022-06-09 インターフェロン誘導ヘリカーゼｃドメイン１（ｉｆｉｈ１）阻害剤による乾癬の治療 Pending JP2024522148A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163209075P 2021-06-10 2021-06-10
US63/209,075 2021-06-10
PCT/US2022/032859 WO2022261341A1 (en) 2021-06-10 2022-06-09 Treatment of psoriasis with interferon induced helicase c domain 1 (ifih1) inhibitors

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JP2024522148A true JP2024522148A (ja) 2024-06-11
JP2024522148A5 JP2024522148A5 (https=) 2025-06-05

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JP2023574638A Pending JP2024522148A (ja) 2021-06-10 2022-06-09 インターフェロン誘導ヘリカーゼｃドメイン１（ｉｆｉｈ１）阻害剤による乾癬の治療

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US (1) US12584174B2 (https=)
EP (1) EP4352224A1 (https=)
JP (1) JP2024522148A (https=)
KR (1) KR20240019766A (https=)
CN (1) CN117441019A (https=)
AU (1) AU2022288634A1 (https=)
CA (1) CA3219620A1 (https=)
IL (1) IL308354A (https=)
MX (1) MX2023014586A (https=)
WO (1) WO2022261341A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025202219A1 (en) * 2024-03-25 2025-10-02 Institut National de la Santé et de la Recherche Médicale Mda5 inhibition as a broad defense and healthspan extending strategy

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018204764A1 (en) * 2017-05-05 2018-11-08 Camp4 Therapeutics Corporation Identification and targeted modulation of gene signaling networks
BR112022006441A2 (pt) * 2019-10-04 2022-07-05 Univ Michigan Regents Métodos para determinar a capacidade de resposta à terapia antifator de necrose tumoral no tratamento da psoríase
EP3858332A1 (en) * 2020-01-31 2021-08-04 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Bottom-up assembly of synthetic extracellular vesicles

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MX2023014586A (es) 2023-12-15
US20230037582A1 (en) 2023-02-09
US12584174B2 (en) 2026-03-24
WO2022261341A1 (en) 2022-12-15
AU2022288634A9 (en) 2023-12-07
CN117441019A (zh) 2024-01-23
KR20240019766A (ko) 2024-02-14
EP4352224A1 (en) 2024-04-17
IL308354A (en) 2024-01-01
AU2022288634A1 (en) 2023-11-30
CA3219620A1 (en) 2022-12-15

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