JP2024521025A5 - - Google Patents
Info
- Publication number
- JP2024521025A5 JP2024521025A5 JP2023568170A JP2023568170A JP2024521025A5 JP 2024521025 A5 JP2024521025 A5 JP 2024521025A5 JP 2023568170 A JP2023568170 A JP 2023568170A JP 2023568170 A JP2023568170 A JP 2023568170A JP 2024521025 A5 JP2024521025 A5 JP 2024521025A5
- Authority
- JP
- Japan
- Prior art keywords
- car
- vector
- gmp
- granulocytes
- macrophages
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163190387P | 2021-05-19 | 2021-05-19 | |
| US63/190,387 | 2021-05-19 | ||
| PCT/US2022/030109 WO2022246112A1 (en) | 2021-05-19 | 2022-05-19 | Chimeric antigen receptor-modified granulocyte-macrophage progenitors for cancer immunotherapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024521025A JP2024521025A (ja) | 2024-05-28 |
| JP2024521025A5 true JP2024521025A5 (https=) | 2025-05-19 |
Family
ID=84141835
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023568170A Pending JP2024521025A (ja) | 2021-05-19 | 2022-05-19 | がん免疫治療のためのキメラ抗原受容体で改変された顆粒球－マクロファージ前駆体 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20240240147A1 (https=) |
| EP (1) | EP4340871A4 (https=) |
| JP (1) | JP2024521025A (https=) |
| KR (1) | KR20240009461A (https=) |
| CN (1) | CN117295515A (https=) |
| AU (1) | AU2022275952A1 (https=) |
| CA (1) | CA3215633A1 (https=) |
| WO (1) | WO2022246112A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024123682A1 (en) * | 2022-12-05 | 2024-06-13 | Shoreline Biosciences, Inc. | Methods and compositions for generating modified pluripotent cells and derivates thereof |
| CN115814108B (zh) * | 2022-12-27 | 2025-04-25 | 华中科技大学 | 一种用于个性化肿瘤治疗的工程化巨噬细胞载药微颗粒制剂及其制备方法 |
| CN116218786B (zh) * | 2023-03-09 | 2024-01-23 | 山东大学齐鲁医院 | 一种多重基因编辑的通用型巨噬细胞及在制备抗肿瘤药物中的应用 |
| JP2026508020A (ja) * | 2023-03-09 | 2026-03-09 | クリエイト・メディシンズ，インコーポレーテッド | インビボ送達構築物の発現を制御するためのｍｉＲＮＡ |
| WO2025046513A1 (en) * | 2023-08-29 | 2025-03-06 | Inceptor Bio, Llc | Methods of manufacturing myeloid-derived cells from hematopoietic stem cells and compositions and uses thereof |
| CN118845835A (zh) * | 2024-09-24 | 2024-10-29 | 杭州阿克索生物科技有限责任公司 | 一种含有细胞因子的组合物及其制备方法和应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016179319A1 (en) * | 2015-05-04 | 2016-11-10 | Cellerant Therapeutics, Inc. | Chimeric antigen receptors with ctla4 signal transduction domains |
| IL315940A (en) * | 2015-07-28 | 2024-11-01 | Univ Pennsylvania | Altered monocytes/macrophages expressing chimeric antigen receptors and their uses |
| US11352439B2 (en) * | 2015-08-13 | 2022-06-07 | Kim Leslie O'Neill | Macrophage CAR (MOTO-CAR) in immunotherapy |
| WO2019135879A1 (en) * | 2018-01-05 | 2019-07-11 | Thunder Biotech, Inc. | Modified macrophages and macrophage precursors and associated methods |
| SG11202007171PA (en) * | 2018-02-02 | 2020-08-28 | Univ Pennsylvania | Modified monocytes/macrophages/dendritic cells expressing chimeric antigen receptors and uses in diseases and disorders associated with protein aggregates |
| CN111004781A (zh) * | 2018-10-08 | 2020-04-14 | 南加利福尼亚大学 | 长期扩增粒细胞-巨噬细胞祖细胞的方法及其应用 |
| CN109266618B (zh) * | 2018-10-18 | 2021-04-23 | 赛元生物科技(杭州)有限公司 | 能够靶向肿瘤细胞的巨噬细胞及其制备方法 |
| US10980836B1 (en) * | 2019-12-11 | 2021-04-20 | Myeloid Therapeutics, Inc. | Therapeutic cell compositions and methods of manufacturing and use thereof |
-
2022
- 2022-05-19 US US18/561,889 patent/US20240240147A1/en active Pending
- 2022-05-19 JP JP2023568170A patent/JP2024521025A/ja active Pending
- 2022-05-19 EP EP22805511.7A patent/EP4340871A4/en active Pending
- 2022-05-19 CA CA3215633A patent/CA3215633A1/en active Pending
- 2022-05-19 AU AU2022275952A patent/AU2022275952A1/en active Pending
- 2022-05-19 KR KR1020237043356A patent/KR20240009461A/ko active Pending
- 2022-05-19 CN CN202280032274.1A patent/CN117295515A/zh active Pending
- 2022-05-19 WO PCT/US2022/030109 patent/WO2022246112A1/en not_active Ceased
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