JP2024520020A - 肝疾患の治療における使用のためのペマフィブラートおよび／またはトホグリフロジン - Google Patents

肝疾患の治療における使用のためのペマフィブラートおよび／またはトホグリフロジン Download PDF

Info

Publication number
JP2024520020A
JP2024520020A JP2023572876A JP2023572876A JP2024520020A JP 2024520020 A JP2024520020 A JP 2024520020A JP 2023572876 A JP2023572876 A JP 2023572876A JP 2023572876 A JP2023572876 A JP 2023572876A JP 2024520020 A JP2024520020 A JP 2024520020A
Authority
JP
Japan
Prior art keywords
patient
pharma
score
acceptable salt
administering
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023572876A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024520020A5 (enExample
Inventor
昇 金田
隆 大島
サンチタ ペンゼ，ショナ
亮平 谷川
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kowa Co Ltd
Original Assignee
Kowa Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co Ltd filed Critical Kowa Co Ltd
Publication of JP2024520020A publication Critical patent/JP2024520020A/ja
Publication of JP2024520020A5 publication Critical patent/JP2024520020A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/423—Oxazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2023572876A 2021-05-27 2022-05-25 肝疾患の治療における使用のためのペマフィブラートおよび／またはトホグリフロジン Pending JP2024520020A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163194088P 2021-05-27 2021-05-27
US63/194,088 2021-05-27
PCT/IB2022/054867 WO2022249071A1 (en) 2021-05-27 2022-05-25 Pemafibrate and/or tofogliflozin for use in treating liver disease

Publications (2)

Publication Number Publication Date
JP2024520020A true JP2024520020A (ja) 2024-05-21
JP2024520020A5 JP2024520020A5 (enExample) 2025-05-08

Family

ID=82020168

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023572876A Pending JP2024520020A (ja) 2021-05-27 2022-05-25 肝疾患の治療における使用のためのペマフィブラートおよび／またはトホグリフロジン

Country Status (10)

Country Link
US (1) US20240277745A1 (enExample)
EP (1) EP4346809A1 (enExample)
JP (1) JP2024520020A (enExample)
KR (1) KR20240013203A (enExample)
CN (1) CN117677385A (enExample)
AU (1) AU2022282651A1 (enExample)
BR (1) BR112023024701A2 (enExample)
CA (1) CA3221073A1 (enExample)
MX (1) MX2023013886A (enExample)
WO (1) WO2022249071A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20250034041A (ko) * 2022-07-15 2025-03-10 교와 가부시키가이샤 혈중 ldl 콜레스테롤 저하제
CN115991682A (zh) * 2023-03-21 2023-04-21 广州佳途科技股份有限公司 一种培马贝特-d4的制备方法及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI696462B (zh) 2013-07-10 2020-06-21 日商興和股份有限公司 非酒精性脂肪性肝疾病治療劑
ES3026786T3 (en) 2017-01-11 2025-06-12 Kowa Co Pemafibrate in combination with a sglt2 inhibitor for the prophylactic or therapeutic treatment of liver diseases nonalcoholic fatty liver disease

Also Published As

Publication number Publication date
CA3221073A1 (en) 2022-12-01
US20240277745A1 (en) 2024-08-22
EP4346809A1 (en) 2024-04-10
BR112023024701A2 (pt) 2024-02-15
MX2023013886A (es) 2024-04-19
KR20240013203A (ko) 2024-01-30
WO2022249071A1 (en) 2022-12-01
AU2022282651A1 (en) 2023-12-07
CN117677385A (zh) 2024-03-08

Similar Documents

Publication Publication Date Title
AU2016229982A1 (en) Methods for the treatment of nonalcoholic fatty liver disease and/or lipodystrophy
US20240173333A1 (en) Treating Alagille Syndrome (ALGS)
EP4706756A2 (en) Semaglutide for the treatment of non-alcoholic steatohepatitis
JP2024520020A (ja) 肝疾患の治療における使用のためのペマフィブラートおよび／またはトホグリフロジン
JP7691971B2 (ja) レビー小体型認知症を処置するための組成物および方法
EP2861244B1 (en) Sleep apnea treatment
JP2019515895A (ja) インスリン抵抗性の治療におけるアゼライン酸エステル
TW202114654A (zh) 包含如sglt 1/2抑制劑的sglt抑制劑之治療
US8445467B2 (en) Reducing risk of type 2 diabetes (T2D)
KR102512518B1 (ko) 페마피브레이트를 함유하는 의약
JP2024539949A (ja) ボクセロトールを投与する方法
AU2018376904A1 (en) FXR agonists for the treatment of liver diseases
US20220347190A1 (en) Treatment comprising fxr agonists
WO2021101910A1 (en) Methods of administering voxelotor
CN112823007A (zh) 用巴瑞替尼治疗原发性胆汁性胆管炎和原发性硬化性胆管炎
CA3034956C (en) TREATMENT OF NON-ALCOHOLIC HEPATIC STEATOSE
CN117462526A (zh) 一种大黄素琥珀酰酯类化合物在非酒精性脂肪肝病中的用途
WO2023202439A1 (zh) 二萜化合物衍生物或其盐在制备防治特应性皮炎的药物中的应用
TW202539665A (zh) Fgfr4抑制劑與ppar促效劑之組合
KR20210020788A (ko) 하이드로퀴논 유도체, 및 오베티콜릭산을 포함하는 비알콜성 지방간염의 예방 또는 치료용 약학조성물
WO2015063602A1 (en) Desmopressin and blood glucose

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20250425

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20250425

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20260428