JP2024517917A5 - - Google Patents
Info
- Publication number
- JP2024517917A5 JP2024517917A5 JP2023569634A JP2023569634A JP2024517917A5 JP 2024517917 A5 JP2024517917 A5 JP 2024517917A5 JP 2023569634 A JP2023569634 A JP 2023569634A JP 2023569634 A JP2023569634 A JP 2023569634A JP 2024517917 A5 JP2024517917 A5 JP 2024517917A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- triazine
- amino
- hydroxy
- piperidyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21173452.0 | 2021-05-12 | ||
| EP21173452 | 2021-05-12 | ||
| EP21209447 | 2021-11-22 | ||
| EP21209447.8 | 2021-11-22 | ||
| EP21215859.6 | 2021-12-20 | ||
| EP21215859 | 2021-12-20 | ||
| PCT/EP2022/062525 WO2022238347A1 (en) | 2021-05-12 | 2022-05-10 | Nlrp3 inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024517917A JP2024517917A (ja) | 2024-04-23 |
| JP2024517917A5 true JP2024517917A5 (https=) | 2025-04-30 |
Family
ID=81941106
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023569634A Pending JP2024517917A (ja) | 2021-05-12 | 2022-05-10 | Ｎｌｒｐ３阻害剤 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US20240208928A1 (https=) |
| EP (2) | EP4337652B1 (https=) |
| JP (1) | JP2024517917A (https=) |
| KR (1) | KR20240007152A (https=) |
| AR (1) | AR125818A1 (https=) |
| AU (1) | AU2022275300A1 (https=) |
| BR (1) | BR112023023527A2 (https=) |
| CA (1) | CA3214626A1 (https=) |
| CL (1) | CL2023003312A1 (https=) |
| CO (1) | CO2023016204A2 (https=) |
| CR (1) | CR20230529A (https=) |
| DK (1) | DK4337652T3 (https=) |
| ES (1) | ES3031704T3 (https=) |
| FI (1) | FI4337652T3 (https=) |
| HR (1) | HRP20250632T1 (https=) |
| HU (1) | HUE071498T2 (https=) |
| IL (1) | IL307188A (https=) |
| LT (1) | LT4337652T (https=) |
| MA (1) | MA64323B1 (https=) |
| MX (1) | MX2023012907A (https=) |
| PE (1) | PE20240126A1 (https=) |
| PL (1) | PL4337652T3 (https=) |
| RS (1) | RS66893B1 (https=) |
| SI (1) | SI4337652T1 (https=) |
| WO (1) | WO2022238347A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11618751B1 (en) | 2022-03-25 | 2023-04-04 | Ventus Therapeutics U.S., Inc. | Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives |
| US11319319B1 (en) | 2021-04-07 | 2022-05-03 | Ventus Therapeutics U.S., Inc. | Compounds for inhibiting NLRP3 and uses thereof |
| IL314025A (en) * | 2022-01-07 | 2024-08-01 | Transthera Sciences Nanjing Inc | Nlrp3 inflammasome inhibitor and uses thereof |
| US12331048B2 (en) | 2022-10-31 | 2025-06-17 | Ventus Therapeutics U.S., Inc. | Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 inhibitors |
| AU2023371859A1 (en) * | 2022-11-04 | 2025-06-12 | Transthera Sciences (Nanjing) , Inc. | Nlrp3 inflammasome inhibitor and use thereof |
| PE20251845A1 (es) * | 2022-12-07 | 2025-07-17 | Hoffmann La Roche | Compuestos novedosos como moduladores de la inhibicion de nlrp3 |
| WO2024158941A2 (en) * | 2023-01-27 | 2024-08-02 | Mwyngil Therapeutics, Inc. | Inhibitors of nlrp3 |
| JP2026511027A (ja) * | 2023-03-20 | 2026-04-10 | インシリコ メディスン アイピー リミティド | Ｎｌｒｐ３インフラマソーム阻害剤及びその使用 |
| WO2024193699A1 (zh) | 2023-03-23 | 2024-09-26 | 成都赜灵生物医药科技有限公司 | 三嗪类化合物及其用途 |
| KR20260027946A (ko) | 2023-06-02 | 2026-03-03 | 머크 샤프 앤드 돔 엘엘씨 | Nod-유사 수용체 단백질 3의 억제제로서 유용한 5,6 불포화 비시클릭 헤테로사이클 |
| IL324489A (en) | 2023-06-29 | 2026-01-01 | Hoffmann La Roche | Triazine derivatives as NLRP3 inhibitors |
| CN121586712A (zh) | 2023-07-28 | 2026-02-27 | 豪夫迈·罗氏有限公司 | 新颖化合物 |
| WO2025059069A1 (en) * | 2023-09-12 | 2025-03-20 | Zomagen Biosciences Ltd | Nlrp3 modulators |
| WO2025153532A1 (en) | 2024-01-16 | 2025-07-24 | NodThera Limited | Nlrp3 inhibitors and glp-1 agonists combination therapies |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6653316B1 (en) * | 1999-05-19 | 2003-11-25 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade |
| AR119731A1 (es) * | 2019-05-17 | 2022-01-05 | Novartis Ag | Inhibidores del inflamasoma nlrp3 |
-
2022
- 2022-05-10 AR ARP220101225A patent/AR125818A1/es unknown
- 2022-05-10 PL PL22728228.2T patent/PL4337652T3/pl unknown
- 2022-05-10 CA CA3214626A patent/CA3214626A1/en active Pending
- 2022-05-10 HU HUE22728228A patent/HUE071498T2/hu unknown
- 2022-05-10 EP EP22728228.2A patent/EP4337652B1/en active Active
- 2022-05-10 LT LTEPPCT/EP2022/062525T patent/LT4337652T/lt unknown
- 2022-05-10 JP JP2023569634A patent/JP2024517917A/ja active Pending
- 2022-05-10 HR HRP20250632TT patent/HRP20250632T1/hr unknown
- 2022-05-10 MX MX2023012907A patent/MX2023012907A/es unknown
- 2022-05-10 DK DK22728228.2T patent/DK4337652T3/da active
- 2022-05-10 MA MA64323A patent/MA64323B1/fr unknown
- 2022-05-10 RS RS20250561A patent/RS66893B1/sr unknown
- 2022-05-10 IL IL307188A patent/IL307188A/en unknown
- 2022-05-10 PE PE2023002971A patent/PE20240126A1/es unknown
- 2022-05-10 FI FIEP22728228.2T patent/FI4337652T3/fi active
- 2022-05-10 SI SI202230138T patent/SI4337652T1/sl unknown
- 2022-05-10 AU AU2022275300A patent/AU2022275300A1/en active Pending
- 2022-05-10 WO PCT/EP2022/062525 patent/WO2022238347A1/en not_active Ceased
- 2022-05-10 BR BR112023023527A patent/BR112023023527A2/pt unknown
- 2022-05-10 KR KR1020237038678A patent/KR20240007152A/ko active Pending
- 2022-05-10 ES ES22728228T patent/ES3031704T3/es active Active
- 2022-05-10 EP EP25167922.1A patent/EP4609865A3/en active Pending
- 2022-05-10 CR CR20230529A patent/CR20230529A/es unknown
-
2023
- 2023-11-07 CL CL2023003312A patent/CL2023003312A1/es unknown
- 2023-11-10 US US18/506,492 patent/US20240208928A1/en active Pending
- 2023-11-29 CO CONC2023/0016204A patent/CO2023016204A2/es unknown
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