JP2024517710A5 - - Google Patents

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Publication number
JP2024517710A5
JP2024517710A5 JP2023565854A JP2023565854A JP2024517710A5 JP 2024517710 A5 JP2024517710 A5 JP 2024517710A5 JP 2023565854 A JP2023565854 A JP 2023565854A JP 2023565854 A JP2023565854 A JP 2023565854A JP 2024517710 A5 JP2024517710 A5 JP 2024517710A5
Authority
JP
Japan
Prior art keywords
targeted peptide
modified
modified aav
capsid protein
aav according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023565854A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024517710A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/026518 external-priority patent/WO2022232257A1/en
Publication of JP2024517710A publication Critical patent/JP2024517710A/ja
Publication of JP2024517710A5 publication Critical patent/JP2024517710A5/ja
Pending legal-status Critical Current

Links

JP2023565854A 2021-04-27 2022-04-27 蝸牛に形質導入するためのアデノ随伴ウイルスベクター Pending JP2024517710A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163180394P 2021-04-27 2021-04-27
US63/180,394 2021-04-27
PCT/US2022/026518 WO2022232257A1 (en) 2021-04-27 2022-04-27 Adeno-associated viral vectors for transduction of cochlea

Publications (2)

Publication Number Publication Date
JP2024517710A JP2024517710A (ja) 2024-04-23
JP2024517710A5 true JP2024517710A5 (https=) 2025-04-21

Family

ID=83847287

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023565854A Pending JP2024517710A (ja) 2021-04-27 2022-04-27 蝸牛に形質導入するためのアデノ随伴ウイルスベクター

Country Status (7)

Country Link
US (1) US20240197920A1 (https=)
EP (1) EP4330413A4 (https=)
JP (1) JP2024517710A (https=)
KR (1) KR20240004536A (https=)
AU (1) AU2022264006A1 (https=)
CA (1) CA3216591A1 (https=)
WO (1) WO2022232257A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN121816425A (zh) * 2023-09-11 2026-04-07 学校法人顺天堂 能够感染内耳的aav变体
US20250152747A1 (en) * 2023-11-15 2025-05-15 Genzyme Corporation Methods of treating gaucher disease and gba-parkinson’s disease
US20250152744A1 (en) * 2023-11-15 2025-05-15 Genzyme Corporation Methods of treating neurodegenerative disorders
WO2025170984A1 (en) * 2024-02-05 2025-08-14 The Children's Hospital Of Philadelphia Cell-type-specific control of gene expression in auditory hair cells

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3762040A4 (en) * 2018-03-05 2022-01-05 Children's Medical Center Corporation COMPOSITIONS AND METHODS OF ADMINISTRATION OF NUCLEIC ACIDS TO COCHLEAR AND VESTIBULAR CELLS
WO2020077295A1 (en) * 2018-10-11 2020-04-16 Decibel Therapeutics, Inc. Aav1 vectors and uses thereof for treatment of otic indications
WO2021067448A1 (en) * 2019-09-30 2021-04-08 Applied Genetic Technologies Corporation Adeno-associated virus (aav) systems for treatment of genetic hearing loss
AU2020366531A1 (en) * 2019-10-18 2022-05-26 Research Institute At Nationwide Children's Hospital Gene therapy targeting cochlear cells
WO2021231538A2 (en) * 2020-05-13 2021-11-18 Akouos, Inc. Compositions and methods for treating kcnq4-associated hearing loss

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