JP2024515344A5 - - Google Patents

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Publication number
JP2024515344A5
JP2024515344A5 JP2023564255A JP2023564255A JP2024515344A5 JP 2024515344 A5 JP2024515344 A5 JP 2024515344A5 JP 2023564255 A JP2023564255 A JP 2023564255A JP 2023564255 A JP2023564255 A JP 2023564255A JP 2024515344 A5 JP2024515344 A5 JP 2024515344A5
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JP
Japan
Prior art keywords
disease
item
composition according
pharmaceutically acceptable
nucleotides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023564255A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024515344A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/025648 external-priority patent/WO2022226127A1/en
Publication of JP2024515344A publication Critical patent/JP2024515344A/ja
Priority to JP2025066627A priority Critical patent/JP2025100729A/ja
Publication of JP2024515344A5 publication Critical patent/JP2024515344A5/ja
Pending legal-status Critical Current

Links

JP2023564255A 2021-04-20 2022-04-20 補体成分3の発現を阻害するための組成物及び方法 Pending JP2024515344A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025066627A JP2025100729A (ja) 2021-04-20 2025-04-15 補体成分3の発現を阻害するための組成物及び方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163177254P 2021-04-20 2021-04-20
US63/177,254 2021-04-20
PCT/US2022/025648 WO2022226127A1 (en) 2021-04-20 2022-04-20 Compositions and methods for inhibiting complement component 3 expression

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025066627A Division JP2025100729A (ja) 2021-04-20 2025-04-15 補体成分3の発現を阻害するための組成物及び方法

Publications (2)

Publication Number Publication Date
JP2024515344A JP2024515344A (ja) 2024-04-09
JP2024515344A5 true JP2024515344A5 (enExample) 2025-04-23

Family

ID=83723122

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2023564255A Pending JP2024515344A (ja) 2021-04-20 2022-04-20 補体成分3の発現を阻害するための組成物及び方法
JP2025066627A Pending JP2025100729A (ja) 2021-04-20 2025-04-15 補体成分3の発現を阻害するための組成物及び方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025066627A Pending JP2025100729A (ja) 2021-04-20 2025-04-15 補体成分3の発現を阻害するための組成物及び方法

Country Status (12)

Country Link
US (1) US20250002908A1 (enExample)
EP (1) EP4326876A4 (enExample)
JP (2) JP2024515344A (enExample)
KR (1) KR20230173116A (enExample)
CN (1) CN117295819A (enExample)
AU (1) AU2022261922A1 (enExample)
BR (1) BR112023021703A2 (enExample)
CA (1) CA3177629A1 (enExample)
CO (1) CO2023014681A2 (enExample)
IL (1) IL307721A (enExample)
MX (1) MX2023012385A (enExample)
WO (1) WO2022226127A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI868755B (zh) 2022-06-24 2025-01-01 丹麥商諾佛 儂迪克股份有限公司 抑制跨膜絲胺酸蛋白酶6(tmprss6)表現的組成物及方法
WO2024169907A1 (zh) * 2023-02-17 2024-08-22 苏州时安生物技术有限公司 一种调节补体C3表达的siRNA、其缀合物和药物组合物及用途
CN121488036A (zh) * 2023-07-21 2026-02-06 上海舶望制药有限公司 用于抑制补体成分3(c3)表达的组合物和方法
WO2025168134A1 (zh) * 2024-02-08 2025-08-14 北京安龙生物医药有限公司 靶向补体成分c3基因的寡核苷酸及其用途
CN121154665B (zh) * 2025-11-21 2026-02-27 天津医科大学第二医院 尿苷在防治糖尿病肾病药物开发过程中及药物中的应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003295600A1 (en) * 2002-11-14 2004-06-15 Dharmacon, Inc. Functional and hyperfunctional sirna
CA2670801A1 (en) * 2005-11-30 2007-06-07 Intradigm Corporation Compositions and methods of using sirna to knockdown gene expression and to improve solid organ and cell transplantation
WO2010042755A2 (en) * 2008-10-08 2010-04-15 Chimeros Inc. Chimeric therapeutics, compositions, and methods for using same
SG10201804960RA (en) * 2013-12-12 2018-07-30 Alnylam Pharmaceuticals Inc Complement component irna compositions and methods of use thereof
RU2019113301A (ru) * 2016-10-17 2020-11-17 Апеллис Фармасьютикалс, Инк. Комбинированная терапия для ингибирования с3
SG11202002940QA (en) * 2017-11-01 2020-04-29 Alnylam Pharmaceuticals Inc Complement component c3 irna compositions and methods of use thereof
US20220017899A1 (en) * 2018-11-23 2022-01-20 Silence Therapeutics Gmbh Nucleic acids for inhibiting expression of c3 in a cell
BR112022003513A2 (pt) * 2019-08-27 2022-05-17 Silence Therapeutics Gmbh Ácidos nucleicos para inibição da expressão de c3 em uma célula
WO2021081026A1 (en) * 2019-10-22 2021-04-29 Alnylam Pharmaceuticals, Inc. Complement component c3 irna compositions and methods of use thereof
IL295517A (en) * 2020-02-14 2022-10-01 Apellis Pharmaceuticals Inc Rnas for complement inhibition
MX2023008469A (es) * 2021-01-22 2023-11-22 Alnylam Pharmaceuticals Inc Oligonucleotidos de doble hebra modificados.
EP4346844A4 (en) * 2021-05-26 2025-09-10 Apellis Pharmaceuticals Inc TREATMENT OF COMPLEMENT-MEDIATED DISORDERS

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