JP2024514995A5 - - Google Patents

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Publication number
JP2024514995A5
JP2024514995A5 JP2023544357A JP2023544357A JP2024514995A5 JP 2024514995 A5 JP2024514995 A5 JP 2024514995A5 JP 2023544357 A JP2023544357 A JP 2023544357A JP 2023544357 A JP2023544357 A JP 2023544357A JP 2024514995 A5 JP2024514995 A5 JP 2024514995A5
Authority
JP
Japan
Prior art keywords
cancer
pharmaceutical composition
composition according
crystalline form
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023544357A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024514995A (ja
JP7565118B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/036260 external-priority patent/WO2023283269A1/en
Publication of JP2024514995A publication Critical patent/JP2024514995A/ja
Publication of JP2024514995A5 publication Critical patent/JP2024514995A5/ja
Application granted granted Critical
Publication of JP7565118B2 publication Critical patent/JP7565118B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2023544357A 2021-07-06 2022-07-06 (s,e)-4-(ジメチルアミノ)-n-(3-(4-(2-ヒドロキシ-1-フェネチルアミノ)-6-フェニルフロ[2,3-d]ピリミジン-5-イル)フェニル)ブタ-2-エナミド遊離塩基の結晶形 Active JP7565118B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163218504P 2021-07-06 2021-07-06
US63/218,504 2021-07-06
PCT/US2022/036260 WO2023283269A1 (en) 2021-07-06 2022-07-06 Crystalline forms of (s, e)-4-(dimethylamino)-n-(3-(4-(2-hydroxy-1-phenylethylamino)-6-phenylfuro[2,3-d]pyrimidin-5-yl)phenyl)but-2-enamide free base

Publications (3)

Publication Number Publication Date
JP2024514995A JP2024514995A (ja) 2024-04-04
JP2024514995A5 true JP2024514995A5 (enExample) 2024-08-20
JP7565118B2 JP7565118B2 (ja) 2024-10-10

Family

ID=84802010

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023544357A Active JP7565118B2 (ja) 2021-07-06 2022-07-06 (s,e)-4-(ジメチルアミノ)-n-(3-(4-(2-ヒドロキシ-1-フェネチルアミノ)-6-フェニルフロ[2,3-d]ピリミジン-5-イル)フェニル)ブタ-2-エナミド遊離塩基の結晶形

Country Status (12)

Country Link
US (2) US12240858B2 (enExample)
EP (1) EP4330259A4 (enExample)
JP (1) JP7565118B2 (enExample)
KR (1) KR102783648B1 (enExample)
CN (1) CN116916922B (enExample)
AU (1) AU2022307875B2 (enExample)
BR (1) BR112023024853A2 (enExample)
CA (1) CA3217088A1 (enExample)
IL (1) IL308946B2 (enExample)
MX (1) MX2023013093A (enExample)
TW (1) TWI809967B (enExample)
WO (1) WO2023283269A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI906763B (zh) * 2024-02-05 2025-12-01 財團法人國家衛生研究院 表皮生長因子受體抑制劑

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8507502B2 (en) * 2008-11-10 2013-08-13 National Health Research Institutes Fused bicyclic and tricyclic pyrimidine compounds as tyrosine kinase inhibitors
KR101301533B1 (ko) * 2010-02-09 2013-09-04 한미사이언스 주식회사 암세포 성장 억제 효과를 갖는 신규 피리미딘 유도체

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