JP2024514344A5 - - Google Patents

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Publication number
JP2024514344A5
JP2024514344A5 JP2023564087A JP2023564087A JP2024514344A5 JP 2024514344 A5 JP2024514344 A5 JP 2024514344A5 JP 2023564087 A JP2023564087 A JP 2023564087A JP 2023564087 A JP2023564087 A JP 2023564087A JP 2024514344 A5 JP2024514344 A5 JP 2024514344A5
Authority
JP
Japan
Prior art keywords
approximately
pharmaceutical composition
seq
amino acid
stable aqueous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023564087A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024514344A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2022/053733 external-priority patent/WO2022224187A1/en
Publication of JP2024514344A publication Critical patent/JP2024514344A/ja
Publication of JP2024514344A5 publication Critical patent/JP2024514344A5/ja
Pending legal-status Critical Current

Links

JP2023564087A 2021-04-21 2022-04-21 高濃度二重特異性抗体製剤 Pending JP2024514344A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163177518P 2021-04-21 2021-04-21
US63/177,518 2021-04-21
US202163180690P 2021-04-28 2021-04-28
US63/180,690 2021-04-28
US202263309230P 2022-02-11 2022-02-11
US63/309,230 2022-02-11
PCT/IB2022/053733 WO2022224187A1 (en) 2021-04-21 2022-04-21 High concentration bispecific antibody formulations

Publications (2)

Publication Number Publication Date
JP2024514344A JP2024514344A (ja) 2024-04-01
JP2024514344A5 true JP2024514344A5 (https=) 2026-01-06

Family

ID=81579656

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023564087A Pending JP2024514344A (ja) 2021-04-21 2022-04-21 高濃度二重特異性抗体製剤

Country Status (17)

Country Link
US (2) US20220395573A1 (https=)
EP (1) EP4326242A1 (https=)
JP (1) JP2024514344A (https=)
KR (1) KR20230174239A (https=)
AU (1) AU2022260814A1 (https=)
BR (1) BR112023021549A2 (https=)
CA (1) CA3217191A1 (https=)
CR (1) CR20230497A (https=)
EC (1) ECSP23080283A (https=)
IL (1) IL307879A (https=)
JO (1) JOP20230263A1 (https=)
MX (1) MX2023012508A (https=)
PE (1) PE20240805A1 (https=)
PH (1) PH12023552883A1 (https=)
TW (1) TW202308689A (https=)
UY (1) UY39734A (https=)
WO (1) WO2022224187A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI907491B (zh) * 2020-08-26 2025-12-11 美商健生生物科技公司 包括雙特異性egfr/c-met抗體之穩定調配物
WO2024003837A1 (en) 2022-06-30 2024-01-04 Janssen Biotech, Inc. Use of anti-egfr/anti-met antibody to treat gastric or esophageal cancer
CA3228195A1 (en) 2023-05-23 2025-06-30 Janssen Biotech, Inc. Methods for treatment of non-small cell lung cancer (nsclc)
AU2024337472A1 (en) 2023-09-05 2026-04-16 Janssen Biotech, Inc. Methods of treating non-small cell lung cancer
CN119700964A (zh) * 2023-09-28 2025-03-28 上海翰森生物医药科技有限公司 一种双特异性抗体在制备治疗癌症的药物中的用途
WO2025079020A1 (en) 2023-10-12 2025-04-17 Janssen Biotech, Inc. First line treatment in egfr exon 20 insertion-mutated advanced non-small cell lung cancer
WO2025158277A1 (en) 2024-01-22 2025-07-31 Janssen Biotech, Inc. Use of amivantamab to treat head and neck cancer
WO2025191459A1 (en) 2024-03-11 2025-09-18 Janssen Biotech, Inc. Use of bispecific anti-egfr/c-met antibodies to treat solid tumors
WO2025227052A1 (en) * 2024-04-26 2025-10-30 Cephalon Llc Doses and formulations of anti-il-15 antibody for the treatment of immune diseases
WO2026022733A1 (en) 2024-07-23 2026-01-29 Janssen Biotech, Inc. Combination therapies for the treatment of colorectal cancer
WO2026022739A1 (en) 2024-07-23 2026-01-29 Janssen Biotech, Inc. Combination therapies for the treatment of colorectal cancer
WO2026042017A1 (en) 2024-08-19 2026-02-26 Janssen Biotech, Inc. Amivantamab in combination with lazertinib for the treatment of non-small cell lung cancer (nsclc)

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0281604B1 (en) 1986-09-02 1993-03-31 Enzon Labs Inc. Single polypeptide chain binding molecules
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
ES2156149T3 (es) 1992-12-04 2001-06-16 Medical Res Council Proteinas de union multivalente y multiespecificas, su fabricacion y su uso.
AUPO591797A0 (en) 1997-03-27 1997-04-24 Commonwealth Scientific And Industrial Research Organisation High avidity polyvalent and polyspecific reagents
CA2450285C (en) * 2001-06-13 2016-08-02 Genmab A/S Human monoclonal antibodies to epidermal growth factor receptor (egfr)
NZ542873A (en) 2003-03-05 2008-07-31 Halozyme Inc Soluble, neutral-active hyaluronidase activity glycoprotein (sHASEGP) that is produced with high yield in a mammalian expression system by introducing nucleic acids that lack a narrow region encoding amino acids in the carboxy terminus of the human PH20 cDNA
ES2569409T3 (es) * 2005-03-08 2016-05-10 Pfizer Products Inc. Composiciones de anticuerpo anti-CTLA-4
TWI395593B (zh) * 2008-03-06 2013-05-11 Halozyme Inc 可活化的基質降解酵素之活體內暫時性控制
BR112012013148A2 (pt) * 2009-12-29 2017-03-21 F Hoffmann - La Roche Ag formulação farmacêutica e uso
HRP20241208T1 (hr) * 2010-04-20 2024-11-22 Genmab A/S Heterodimerni proteini koji sadrže fc fragment protutijela i postupci za njihovu proizvodnju
MX361088B (es) * 2012-11-21 2018-11-26 Janssen Biotech Inc Anticuerpos del receptor del factor de crecimiento epidérmico aislado/del receptor del factor de crecimiento de hepatocitos (egfr/c-met) biespecíficos.
TWI907491B (zh) * 2020-08-26 2025-12-11 美商健生生物科技公司 包括雙特異性egfr/c-met抗體之穩定調配物
EP4210702A1 (en) * 2020-09-14 2023-07-19 JANSSEN Pharmaceutica NV Fgfr inhibitor combination therapies

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