JP2024513126A - ループまたは末端でペプチドタグと相互作用するポリペプチドおよびその使用 - Google Patents

ループまたは末端でペプチドタグと相互作用するポリペプチドおよびその使用 Download PDF

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Publication number
JP2024513126A
JP2024513126A JP2023561866A JP2023561866A JP2024513126A JP 2024513126 A JP2024513126 A JP 2024513126A JP 2023561866 A JP2023561866 A JP 2023561866A JP 2023561866 A JP2023561866 A JP 2023561866A JP 2024513126 A JP2024513126 A JP 2024513126A
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JP
Japan
Prior art keywords
seq
amino acid
polypeptide
acid sequence
peptide
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JP2023561866A
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English (en)
Japanese (ja)
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JPWO2022214795A5 (https=
JP2024513126A5 (https=
Inventor
ハワース、マーク
ヤーダヴ、ビカシュ
フェルラ、マッテオ
Original Assignee
オックスフォード ユニヴァーシティ イノヴェーション リミテッド
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Publication of JP2024513126A publication Critical patent/JP2024513126A/ja
Publication of JPWO2022214795A5 publication Critical patent/JPWO2022214795A5/ja
Publication of JP2024513126A5 publication Critical patent/JP2024513126A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/90—Fusion polypeptide containing a motif for post-translational modification

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2023561866A 2021-04-08 2022-04-01 ループまたは末端でペプチドタグと相互作用するポリペプチドおよびその使用 Pending JP2024513126A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB2104999.4A GB202104999D0 (en) 2021-04-08 2021-04-08 Polypeptides that interact with peptide tags at loops or termini and uses thereof
GB2104999.4 2021-04-08
PCT/GB2022/050841 WO2022214795A1 (en) 2021-04-08 2022-04-01 Polypeptides that interact with peptide tags at loops or termini and uses thereof

Publications (3)

Publication Number Publication Date
JP2024513126A true JP2024513126A (ja) 2024-03-21
JPWO2022214795A5 JPWO2022214795A5 (https=) 2025-04-09
JP2024513126A5 JP2024513126A5 (https=) 2025-04-09

Family

ID=75949566

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023561866A Pending JP2024513126A (ja) 2021-04-08 2022-04-01 ループまたは末端でペプチドタグと相互作用するポリペプチドおよびその使用

Country Status (10)

Country Link
US (1) US20240182530A1 (https=)
EP (1) EP4320140A1 (https=)
JP (1) JP2024513126A (https=)
KR (1) KR20230165919A (https=)
CN (1) CN117062828A (https=)
AU (1) AU2022254857A1 (https=)
BR (1) BR112023020647A2 (https=)
CA (1) CA3214614A1 (https=)
GB (1) GB202104999D0 (https=)
WO (1) WO2022214795A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202313175D0 (en) 2023-08-30 2023-10-11 Univ Oxford Innovation Ltd A bivalent polypeptide scaffold and uses thereof
GB202315107D0 (en) 2023-10-02 2023-11-15 Univ Oxford Innovation Ltd Polypeptides and peptide tags capable of spontaneous isopeptide bond formation at low temperature and low pH and uses thereof
GB202317925D0 (en) 2023-11-23 2024-01-10 Spybiotech Ltd Vaccines

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018521640A (ja) * 2015-06-05 2018-08-09 オックスフォード ユニバーシティ イノベーション リミテッドＯｘｆｏｒｄ Ｕｎｉｖｅｒｓｉｔｙ Ｉｎｎｏｖａｔｉｏｎ Ｌｉｍｉｔｅｄ 融合タンパク質を合成するための方法および製品
JP2020516314A (ja) * 2017-04-10 2020-06-11 オックスフォード ユニヴァーシティ イノヴェーション リミテッド ペプチドリガーゼ及びその使用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU530410B2 (en) 1978-02-21 1983-07-14 Sintef Preparing aqueous emulsions
GB201002362D0 (en) 2010-02-11 2010-03-31 Isis Innovation Peptide tag systems that spontaneously form an irreversible link to protein partners via isopeptide bonds
GB201706430D0 (en) 2017-04-24 2017-06-07 Univ Oxford Innovation Ltd Proteins and peptide tags with enhanced rate of spontaneous isopeptide bond formation and uses thereof
GB201819850D0 (en) 2018-12-05 2019-01-23 Univ Oxford Innovation Ltd Polypeptide and its use in affinity purification
GB201903479D0 (en) 2019-03-14 2019-05-01 Univ Oxford Innovation Ltd Polypeptide with enchanced rate of spontaneous isopeptide bond formation with it's peptide tag partner and uses thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018521640A (ja) * 2015-06-05 2018-08-09 オックスフォード ユニバーシティ イノベーション リミテッドＯｘｆｏｒｄ Ｕｎｉｖｅｒｓｉｔｙ Ｉｎｎｏｖａｔｉｏｎ Ｌｉｍｉｔｅｄ 融合タンパク質を合成するための方法および製品
JP2020516314A (ja) * 2017-04-10 2020-06-11 オックスフォード ユニヴァーシティ イノヴェーション リミテッド ペプチドリガーゼ及びその使用

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KHAIRIL ANUAR, IRSYAD N. A. ET AL., NATURE COMMUNICATIONS, vol. 10, no. 1, JPN6026006138, 2019, ISSN: 0005797118 *

Also Published As

Publication number Publication date
AU2022254857A1 (en) 2023-11-23
WO2022214795A1 (en) 2022-10-13
KR20230165919A (ko) 2023-12-05
US20240182530A1 (en) 2024-06-06
CN117062828A (zh) 2023-11-14
CA3214614A1 (en) 2022-10-13
BR112023020647A2 (pt) 2023-12-05
EP4320140A1 (en) 2024-02-14
GB202104999D0 (en) 2021-05-26

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