JP2024511292A - 染色体相互作用マーカー - Google Patents

染色体相互作用マーカー Download PDF

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Publication number
JP2024511292A
JP2024511292A JP2023553436A JP2023553436A JP2024511292A JP 2024511292 A JP2024511292 A JP 2024511292A JP 2023553436 A JP2023553436 A JP 2023553436A JP 2023553436 A JP2023553436 A JP 2023553436A JP 2024511292 A JP2024511292 A JP 2024511292A
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JP
Japan
Prior art keywords
cancer
immunotherapy
individual
chromosomal
dna
Prior art date
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Pending
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JP2023553436A
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English (en)
Japanese (ja)
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JP2024511292A5 (enExample
Inventor
セルバム ラマダス、アロウル
ハンター、ユアン
アクーリチェフ、アレクサンドル
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Oxford Biodynamics PLC
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Oxford Biodynamics PLC
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Publication date
Application filed by Oxford Biodynamics PLC filed Critical Oxford Biodynamics PLC
Publication of JP2024511292A publication Critical patent/JP2024511292A/ja
Publication of JP2024511292A5 publication Critical patent/JP2024511292A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2531/00—Reactions of nucleic acids characterised by
    • C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
    • C12Q2531/113—PCR
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2023553436A 2021-03-04 2022-03-03 染色体相互作用マーカー Pending JP2024511292A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163156659P 2021-03-04 2021-03-04
US63/156,659 2021-03-04
US202163282284P 2021-11-23 2021-11-23
US63/282,284 2021-11-23
PCT/GB2022/050561 WO2022185062A1 (en) 2021-03-04 2022-03-03 Chromosome interaction markers

Publications (2)

Publication Number Publication Date
JP2024511292A true JP2024511292A (ja) 2024-03-13
JP2024511292A5 JP2024511292A5 (enExample) 2025-03-03

Family

ID=80735500

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023553436A Pending JP2024511292A (ja) 2021-03-04 2022-03-03 染色体相互作用マーカー

Country Status (15)

Country Link
US (1) US20240229135A9 (enExample)
EP (1) EP4301874B1 (enExample)
JP (1) JP2024511292A (enExample)
KR (1) KR20240006020A (enExample)
AU (1) AU2022230780B2 (enExample)
BR (1) BR112023017802A2 (enExample)
CA (1) CA3209544A1 (enExample)
ES (1) ES3029416T3 (enExample)
GB (1) GB2618727B (enExample)
HU (1) HUE071359T2 (enExample)
IL (1) IL304883A (enExample)
PL (1) PL4301874T3 (enExample)
TW (1) TW202302862A (enExample)
WO (1) WO2022185062A1 (enExample)
ZA (1) ZA202309162B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202412610D0 (en) * 2024-08-28 2024-10-09 Oxford BioDynamics PLC Screening method

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021501592A (ja) * 2017-11-03 2021-01-21 オックスフォード バイオダイナミックス リミテッド 遺伝子調節

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020198676A1 (en) * 2019-03-28 2020-10-01 Bristol-Myers Squibb Company Methods of treating tumor
GB2626699B (en) * 2019-05-08 2024-11-20 Oxford BioDynamics PLC Chromosome Conformation Markers of Prostate Cancer and Lymphoma
WO2021228888A1 (en) * 2020-05-12 2021-11-18 Asylia Diagnostics Biomarkers for hyperprogressive disease and therapy response after immunotherapy

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021501592A (ja) * 2017-11-03 2021-01-21 オックスフォード バイオダイナミックス リミテッド 遺伝子調節

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ALEXANDRE AKOULITCHEV ET AL., JOURNAL OF CLINICAL ONCOLOGY, vol. Vol. 35、Issue 15, JPN6022042014, 30 May 2017 (2017-05-30), ISSN: 0005781761 *

Also Published As

Publication number Publication date
US20240229135A9 (en) 2024-07-11
BR112023017802A2 (pt) 2023-12-12
TW202302862A (zh) 2023-01-16
AU2022230780A1 (en) 2023-10-12
EP4301874C0 (en) 2025-04-23
HUE071359T2 (hu) 2025-08-28
ES3029416T3 (en) 2025-06-24
EP4301874B1 (en) 2025-04-23
GB202313067D0 (en) 2023-10-11
WO2022185062A1 (en) 2022-09-09
AU2022230780B2 (en) 2024-05-23
ZA202309162B (en) 2025-03-26
GB2618727A (en) 2023-11-15
US20240132959A1 (en) 2024-04-25
PL4301874T3 (pl) 2025-06-23
GB2618727B (en) 2024-07-17
KR20240006020A (ko) 2024-01-12
CA3209544A1 (en) 2022-09-09
EP4301874A1 (en) 2024-01-10
IL304883A (en) 2023-10-01

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