CA3209544A1 - Chromosome interaction markers - Google Patents

Chromosome interaction markers Download PDF

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Publication number
CA3209544A1
CA3209544A1 CA3209544A CA3209544A CA3209544A1 CA 3209544 A1 CA3209544 A1 CA 3209544A1 CA 3209544 A CA3209544 A CA 3209544A CA 3209544 A CA3209544 A CA 3209544A CA 3209544 A1 CA3209544 A1 CA 3209544A1
Authority
CA
Canada
Prior art keywords
cancer
individual
chromosome
immunotherapy
probe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3209544A
Other languages
English (en)
French (fr)
Inventor
Aroul Selvam Ramadass
Ewan HUNTER
Alexandre Akoulitchev
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxford Biodynamics PLC
Original Assignee
Oxford Biodynamics PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford Biodynamics PLC filed Critical Oxford Biodynamics PLC
Publication of CA3209544A1 publication Critical patent/CA3209544A1/en
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2531/00—Reactions of nucleic acids characterised by
    • C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
    • C12Q2531/113—PCR
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA3209544A 2021-03-04 2022-03-03 Chromosome interaction markers Pending CA3209544A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163156659P 2021-03-04 2021-03-04
US63/156,659 2021-03-04
US202163282284P 2021-11-23 2021-11-23
US63/282,284 2021-11-23
PCT/GB2022/050561 WO2022185062A1 (en) 2021-03-04 2022-03-03 Chromosome interaction markers

Publications (1)

Publication Number Publication Date
CA3209544A1 true CA3209544A1 (en) 2022-09-09

Family

ID=80735500

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3209544A Pending CA3209544A1 (en) 2021-03-04 2022-03-03 Chromosome interaction markers

Country Status (15)

Country Link
US (1) US20240229135A9 (enExample)
EP (1) EP4301874B1 (enExample)
JP (1) JP2024511292A (enExample)
KR (1) KR20240006020A (enExample)
AU (1) AU2022230780B2 (enExample)
BR (1) BR112023017802A2 (enExample)
CA (1) CA3209544A1 (enExample)
ES (1) ES3029416T3 (enExample)
GB (1) GB2618727B (enExample)
HU (1) HUE071359T2 (enExample)
IL (1) IL304883A (enExample)
PL (1) PL4301874T3 (enExample)
TW (1) TW202302862A (enExample)
WO (1) WO2022185062A1 (enExample)
ZA (1) ZA202309162B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202412610D0 (en) * 2024-08-28 2024-10-09 Oxford BioDynamics PLC Screening method

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111511930B (zh) * 2017-11-03 2024-11-22 牛津生物动力有限责任公司 通过染色体相互作用遗传调节免疫响应
WO2020198676A1 (en) * 2019-03-28 2020-10-01 Bristol-Myers Squibb Company Methods of treating tumor
GB2626699B (en) * 2019-05-08 2024-11-20 Oxford BioDynamics PLC Chromosome Conformation Markers of Prostate Cancer and Lymphoma
WO2021228888A1 (en) * 2020-05-12 2021-11-18 Asylia Diagnostics Biomarkers for hyperprogressive disease and therapy response after immunotherapy

Also Published As

Publication number Publication date
JP2024511292A (ja) 2024-03-13
US20240229135A9 (en) 2024-07-11
BR112023017802A2 (pt) 2023-12-12
TW202302862A (zh) 2023-01-16
AU2022230780A1 (en) 2023-10-12
EP4301874C0 (en) 2025-04-23
HUE071359T2 (hu) 2025-08-28
ES3029416T3 (en) 2025-06-24
EP4301874B1 (en) 2025-04-23
GB202313067D0 (en) 2023-10-11
WO2022185062A1 (en) 2022-09-09
AU2022230780B2 (en) 2024-05-23
ZA202309162B (en) 2025-03-26
GB2618727A (en) 2023-11-15
US20240132959A1 (en) 2024-04-25
PL4301874T3 (pl) 2025-06-23
GB2618727B (en) 2024-07-17
KR20240006020A (ko) 2024-01-12
EP4301874A1 (en) 2024-01-10
IL304883A (en) 2023-10-01

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