JP2024508347A5 - - Google Patents
Info
- Publication number
- JP2024508347A5 JP2024508347A5 JP2023537357A JP2023537357A JP2024508347A5 JP 2024508347 A5 JP2024508347 A5 JP 2024508347A5 JP 2023537357 A JP2023537357 A JP 2023537357A JP 2023537357 A JP2023537357 A JP 2023537357A JP 2024508347 A5 JP2024508347 A5 JP 2024508347A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- sulfur
- nitrogen
- oxygen
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063128680P | 2020-12-21 | 2020-12-21 | |
| US63/128,680 | 2020-12-21 | ||
| US202163223971P | 2021-07-20 | 2021-07-20 | |
| US63/223,971 | 2021-07-20 | ||
| US202163287390P | 2021-12-08 | 2021-12-08 | |
| US63/287,390 | 2021-12-08 | ||
| PCT/US2021/064339 WO2022140252A1 (en) | 2020-12-21 | 2021-12-20 | Nanomaterials comprising ester-linked acetals |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024508347A JP2024508347A (ja) | 2024-02-27 |
| JP2024508347A5 true JP2024508347A5 (enExample) | 2024-12-27 |
Family
ID=82159839
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023537357A Pending JP2024508347A (ja) | 2020-12-21 | 2021-12-20 | エステル結合アセタールを含むナノ材料 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20230331657A1 (enExample) |
| EP (1) | EP4262819A4 (enExample) |
| JP (1) | JP2024508347A (enExample) |
| KR (1) | KR20230133986A (enExample) |
| AU (1) | AU2021410666A1 (enExample) |
| CA (1) | CA3203295A1 (enExample) |
| IL (1) | IL303365A (enExample) |
| MX (1) | MX2023007137A (enExample) |
| WO (1) | WO2022140252A1 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3145913A1 (en) | 2019-07-29 | 2021-02-04 | James Everett Dahlman | Nanomaterials containing constrained lipids and uses thereof |
| IL294318A (en) | 2020-01-09 | 2022-08-01 | Guide Therapeutics Llc | Nanomaterials |
| JP2024503976A (ja) * | 2020-12-21 | 2024-01-30 | ビーム セラピューティクス インク． | アセタールを含むナノ材料 |
| CN116761888A (zh) | 2021-01-20 | 2023-09-15 | 比姆医疗股份有限公司 | 纳米材料 |
| EP4281080A4 (en) | 2021-01-20 | 2025-09-24 | Beam Therapeutics Inc | NANOMATERIALS COMPRISING A BIODEGRADABLE ELEMENT |
| AU2022268465A1 (en) * | 2021-05-06 | 2023-03-09 | Stemirna Therapeutics Co., Ltd. | A lipid |
| TW202328067A (zh) | 2021-09-14 | 2023-07-16 | 美商雷納嘉德醫療管理公司 | 環狀脂質及其使用方法 |
| CN118317944A (zh) | 2021-09-14 | 2024-07-09 | 雷纳嘉德医疗管理公司 | 非环状脂质及其使用方法 |
| TW202334080A (zh) | 2021-11-08 | 2023-09-01 | 美商歐納醫療公司 | 用於遞送環狀聚核苷酸之脂質奈米粒子組合物 |
| EP4452925A1 (en) * | 2021-12-20 | 2024-10-30 | Beam Therapeutics Inc. | Nanomaterial comprising diamines |
| EP4452928A1 (en) | 2021-12-23 | 2024-10-30 | Renagade Therapeutics Management Inc. | Constrained lipids and methods of use thereof |
| TW202330457A (zh) * | 2022-01-19 | 2023-08-01 | 大陸商蘇州艾博生物科技有限公司 | 脂質化合物和脂質奈米顆粒組合物 |
| CA3260437A1 (en) | 2022-07-20 | 2024-01-25 | Beam Therapeutics Inc. | NANOMATERIALS INCLUDING TRIOLS |
| EP4615425A1 (en) | 2022-11-11 | 2025-09-17 | Beam Therapeutics Inc. | Base editing of transthyretin gene |
| WO2024112775A1 (en) * | 2022-11-25 | 2024-05-30 | Beam Therapeutics Inc. | Compositions and methods for editing a transthyretin gene |
| CN120418427A (zh) | 2022-12-23 | 2025-08-01 | 因特利亚治疗公司 | 用于基因组编辑的系统和方法 |
| WO2024140546A1 (zh) * | 2022-12-26 | 2024-07-04 | 北京新合睿恩生物医疗科技有限公司 | 一种阳离子脂质化合物及制备方法和应用、mRNA递送系统 |
| AU2024236558A1 (en) * | 2023-03-15 | 2025-10-09 | Renagade Therapeutics Management Inc. | Delivery of gene editing systems and methods of use thereof |
| AU2024279278A1 (en) | 2023-05-31 | 2025-12-18 | Capstan Therapeutics, Inc. | Lipid nanoparticle formulations and compositions |
| WO2025000542A1 (en) * | 2023-06-30 | 2025-01-02 | Shanghai Vitalgen Biopharma Co., Ltd. | Ionizable cationic lipid compounds for delivery of biologically active agents |
| KR20260046133A (ko) * | 2023-07-19 | 2026-04-06 | 젠에디트바이오 리미티드 | 지질 및 지질 나노입자 |
| AU2024325364A1 (en) * | 2023-08-16 | 2026-03-26 | Beam Therapeutics Inc. | Ionizable lipids with branched head groups |
| WO2025159966A1 (en) * | 2024-01-23 | 2025-07-31 | Beam Therapeutics Inc. | Compositions and methods for altering a nucleobase in a transthyretin polynucleotide |
| WO2025212851A2 (en) | 2024-04-03 | 2025-10-09 | Orbital Therapeutics, Inc. | mRNA COMPOSITIONS AND USES THEREOF IN VARICELLA ZOSTER VIRUS VACCINES |
| WO2025259931A1 (en) | 2024-06-14 | 2025-12-18 | Orbital Therapeutics, Inc. | Compositions and methods for rna circularization |
| WO2026006203A2 (en) | 2024-06-24 | 2026-01-02 | Orbital Therapeutics, Inc. | Compositions and methods for making circular rna |
| WO2026003582A2 (en) | 2024-06-27 | 2026-01-02 | Axelyf ehf. | Lipids and lipid nanoparticles |
| WO2026006687A1 (en) | 2024-06-28 | 2026-01-02 | Orbital Therapeutics, Inc. | Circular rna compositions and uses thereof for diseases caused by varicella-zoster virus |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2075970B (en) * | 1980-04-10 | 1984-05-02 | Nippon Paint Co Ltd | Polymerisable amino acid compounds and their production |
| US20030083272A1 (en) | 1997-09-19 | 2003-05-01 | Lahive & Cockfield, Llp | Sense mrna therapy |
| DE19940641A1 (de) * | 1999-08-26 | 2001-03-01 | Basf Ag | Verfahren zur Herstellung von 4-Acyl-aminosäureestern und N-Acyl-Aminoacetalen |
| CA2721333C (en) | 2008-04-15 | 2020-12-01 | Protiva Biotherapeutics, Inc. | Novel lipid formulations for nucleic acid delivery |
| JP6948313B6 (ja) | 2015-09-17 | 2022-01-14 | モデルナティエックス インコーポレイテッド | 治療剤の細胞内送達のための化合物および組成物 |
| CN110214183A (zh) | 2016-08-03 | 2019-09-06 | 哈佛大学的校长及成员们 | 腺苷核碱基编辑器及其用途 |
| BR112019015797A2 (pt) * | 2017-02-01 | 2020-03-17 | Modernatx, Inc. | Composições de mrna terapêuticas imunomoduladoras que codificam peptídeos de mutação de oncogene de ativação |
| US20220009878A1 (en) * | 2018-10-02 | 2022-01-13 | Intellia Therapeutics, Inc. | Ionizable amine lipids |
| CN114127044A (zh) * | 2019-04-25 | 2022-03-01 | 英特利亚治疗股份有限公司 | 可电离的胺类脂质和脂质纳米颗粒 |
| IL294318A (en) * | 2020-01-09 | 2022-08-01 | Guide Therapeutics Llc | Nanomaterials |
| AU2021269137A1 (en) * | 2020-05-08 | 2022-12-15 | Orna Therapeutics, Inc. | Circular RNA compositions and methods |
-
2021
- 2021-12-20 EP EP21911970.8A patent/EP4262819A4/en active Pending
- 2021-12-20 JP JP2023537357A patent/JP2024508347A/ja active Pending
- 2021-12-20 KR KR1020237023906A patent/KR20230133986A/ko active Pending
- 2021-12-20 IL IL303365A patent/IL303365A/en unknown
- 2021-12-20 CA CA3203295A patent/CA3203295A1/en active Pending
- 2021-12-20 MX MX2023007137A patent/MX2023007137A/es unknown
- 2021-12-20 WO PCT/US2021/064339 patent/WO2022140252A1/en not_active Ceased
- 2021-12-20 AU AU2021410666A patent/AU2021410666A1/en active Pending
-
2023
- 2023-06-20 US US18/211,857 patent/US20230331657A1/en active Pending
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