JP2024508047A5 - - Google Patents
Info
- Publication number
- JP2024508047A5 JP2024508047A5 JP2023572670A JP2023572670A JP2024508047A5 JP 2024508047 A5 JP2024508047 A5 JP 2024508047A5 JP 2023572670 A JP2023572670 A JP 2023572670A JP 2023572670 A JP2023572670 A JP 2023572670A JP 2024508047 A5 JP2024508047 A5 JP 2024508047A5
- Authority
- JP
- Japan
- Prior art keywords
- approximately
- lipid
- average
- molar ratio
- lipids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163147959P | 2021-02-10 | 2021-02-10 | |
| US63/147,959 | 2021-02-10 | ||
| US202163181899P | 2021-04-29 | 2021-04-29 | |
| US202163181917P | 2021-04-29 | 2021-04-29 | |
| US63/181,917 | 2021-04-29 | ||
| US63/181,899 | 2021-04-29 | ||
| PCT/US2022/011463 WO2022173531A1 (en) | 2021-02-10 | 2022-01-06 | Compounds, compositions, and methods of using thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024508047A JP2024508047A (ja) | 2024-02-21 |
| JP2024508047A5 true JP2024508047A5 (https=) | 2025-01-16 |
Family
ID=82837914
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023572670A Pending JP2024508047A (ja) | 2021-02-10 | 2022-01-06 | 化合物、組成物、及びそれらの使用方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20240173267A1 (https=) |
| EP (1) | EP4291201A4 (https=) |
| JP (1) | JP2024508047A (https=) |
| KR (1) | KR20230155448A (https=) |
| AU (1) | AU2022218642A1 (https=) |
| BR (1) | BR112023015937A2 (https=) |
| CA (1) | CA3207753A1 (https=) |
| IL (1) | IL305064A (https=) |
| MX (1) | MX2023009345A (https=) |
| WO (1) | WO2022173531A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2024542188A (ja) * | 2021-11-16 | 2024-11-13 | セイル バイオメディシンズ インコーポレイテッド | 新規イオン化可能な脂質および脂質ナノ粒子ならびにそれらを使用する方法 |
| CN119789852A (zh) * | 2022-08-30 | 2025-04-08 | 再生技术有限责任公司 | 用于递送rna的组合物和方法 |
| WO2024052923A1 (en) * | 2022-09-11 | 2024-03-14 | Barcode Nanotech Ltd. | Ionizable lipids and compositions comprising same |
| KR20250126155A (ko) | 2022-11-04 | 2025-08-22 | 라이프 에디트 테라퓨틱스, 인크. | 내부 삽입 부위를 갖는 진화된 아데닌 데아미나제 및 rna-가이드 뉴클레아제 융합 단백질 및 사용 방법 |
| CN115932098B (zh) * | 2022-12-14 | 2024-12-24 | 辅必成（上海）医药科技有限公司 | 一种用hplc法分离胆固醇、表胆甾醇和异胆固醇的方法 |
| CN115677518B (zh) * | 2023-01-05 | 2023-04-14 | 北京悦康科创医药科技股份有限公司 | 用于递送核酸的可电离阳离子脂质化合物和组合物及用途 |
| US20240366521A1 (en) * | 2023-01-17 | 2024-11-07 | Qana Therapeutics Inc. | Nanoparticles and methods of use |
| CN120826390A (zh) * | 2023-01-31 | 2025-10-21 | 安斯泰来制药株式会社 | 具有环状胺的氨甲酰基脂质或脲脂质、含有其的脂质纳米粒子和药物组合物 |
| WO2024178397A2 (en) | 2023-02-24 | 2024-08-29 | Elevatebio Technologies, Inc. | Modified immune effector cells and methods of use |
| CN118666726A (zh) * | 2023-03-17 | 2024-09-20 | 尧唐(上海)生物科技有限公司 | 递送治疗剂的脂质化合物及其制备方法与应用 |
| WO2024226779A1 (en) * | 2023-04-26 | 2024-10-31 | Saliogen Therapeutics, Inc. | Lipid nanoparticle (lnp) formulations |
| WO2025022367A2 (en) | 2023-07-27 | 2025-01-30 | Life Edit Therapeutics, Inc. | Rna-guided nucleases and active fragments and variants thereof and methods of use |
| WO2025083619A1 (en) | 2023-10-18 | 2025-04-24 | Life Edit Therapeutics, Inc. | Rna-guided nucleases and acive fragments and variants thereof and methods of use |
| CN117603064B (zh) * | 2023-11-08 | 2025-09-16 | 上海凌凯科技股份有限公司 | 一种三（羟基烷基）甲基胺的制备方法及中间体 |
| WO2025166238A1 (en) | 2024-01-31 | 2025-08-07 | Orna Therapeutics, Inc. | Fast-shedding polyethylene glycol lipids |
| WO2025174908A1 (en) | 2024-02-12 | 2025-08-21 | Life Edit Therapeutics, Inc. | Novel rna-guided nucleases and proteins for polymerase editing |
| WO2026003754A1 (en) | 2024-06-25 | 2026-01-02 | Life Edit Therapeutics, Inc. | Novel reverse transcriptases and uses thereof |
| WO2026003582A2 (en) | 2024-06-27 | 2026-01-02 | Axelyf ehf. | Lipids and lipid nanoparticles |
| WO2026029046A1 (ja) * | 2024-07-30 | 2026-02-05 | アステラス製薬株式会社 | 側鎖に環状基を有するウレア又はカーバメート脂質、その脂質ナノ粒子、及びその医薬組成物 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2341149T3 (en) | 2005-08-26 | 2017-02-27 | Dupont Nutrition Biosci Aps | Use of CRISPR-associated genes (Cas) |
| BRPI0716427A2 (pt) | 2006-08-11 | 2014-03-11 | Dow Agrosciences Llc | Recombinação homóloga mediada por nuclease de apêndice de zinco |
| WO2010011961A2 (en) | 2008-07-25 | 2010-01-28 | University Of Georgia Research Foundation, Inc. | Prokaryotic rnai-like system and methods of use |
| US20100076057A1 (en) | 2008-09-23 | 2010-03-25 | Northwestern University | TARGET DNA INTERFERENCE WITH crRNA |
| US9404098B2 (en) | 2008-11-06 | 2016-08-02 | University Of Georgia Research Foundation, Inc. | Method for cleaving a target RNA using a Cas6 polypeptide |
| US10662227B2 (en) | 2008-11-07 | 2020-05-26 | Dupont Nutrition Biosciences Aps | Bifidobacteria CRISPR sequences |
| CN103261213A (zh) | 2010-10-20 | 2013-08-21 | 杜邦营养生物科学有限公司 | 乳球菌CRISPR-Cas序列 |
| AU2012249390B2 (en) | 2011-04-27 | 2017-03-30 | Amyris, Inc. | Methods for genomic modification |
| WO2013016058A1 (en) * | 2011-07-22 | 2013-01-31 | Merck Sharp & Dohme Corp. | Novel bis-nitrogen containing cationic lipids for oligonucleotide delivery |
| PE20181541A1 (es) * | 2011-10-27 | 2018-09-26 | Massachusetts Inst Technology | Derivados de aminoacidos funcionalizados en la terminal n capaces de formar microesferas encapsuladoras de farmaco |
| AU2014348212C1 (en) * | 2013-11-18 | 2018-11-29 | Arcturus Therapeutics, Inc. | Ionizable cationic lipid for RNA delivery |
| JP6637988B2 (ja) | 2014-11-18 | 2020-01-29 | アークトゥルス セラピューティクス， インコーポレイテッド | Ｒｎａ送達のためのイオン化可能カチオン性脂質 |
| US10167253B2 (en) * | 2015-06-24 | 2019-01-01 | Nitto Denko Corporation | Ionizable compounds and compositions and uses thereof |
| US10526284B2 (en) * | 2016-12-21 | 2020-01-07 | Arcturus Therapeutics, Inc. | Ionizable cationic lipid for RNA delivery |
| US10383952B2 (en) * | 2016-12-21 | 2019-08-20 | Arcturus Therapeutics, Inc. | Ionizable cationic lipid for RNA delivery |
| WO2018183901A1 (en) * | 2017-03-30 | 2018-10-04 | The Government Of The United States Of America As Represented By The Secretary Of The Army | Nucleic acid vaccine composition comprising a lipid formulation, and method of increasing the potency of nucleic acid vaccines |
| EP3675817A1 (en) * | 2017-08-31 | 2020-07-08 | Modernatx, Inc. | Methods of making lipid nanoparticles |
| US20190314291A1 (en) * | 2018-01-30 | 2019-10-17 | Modernatx, Inc. | Compositions and methods for delivery of agents to immune cells |
| WO2019191780A1 (en) * | 2018-03-30 | 2019-10-03 | Arcturus Therapeutics, Inc. | Lipid particles for nucleic acid delivery |
| MX2021005448A (es) * | 2018-11-13 | 2021-08-11 | Oncorus Inc | Polinucleotidos encapsulados y metodos de uso. |
| MA55896A (fr) | 2019-05-07 | 2022-03-16 | Modernatx Inc | Polynucléotides servant à perturber l'activité de cellule immunitaire et procédés pour les utiliser |
-
2022
- 2022-01-06 CA CA3207753A patent/CA3207753A1/en active Pending
- 2022-01-06 JP JP2023572670A patent/JP2024508047A/ja active Pending
- 2022-01-06 MX MX2023009345A patent/MX2023009345A/es unknown
- 2022-01-06 AU AU2022218642A patent/AU2022218642A1/en active Pending
- 2022-01-06 IL IL305064A patent/IL305064A/en unknown
- 2022-01-06 KR KR1020237030352A patent/KR20230155448A/ko active Pending
- 2022-01-06 WO PCT/US2022/011463 patent/WO2022173531A1/en not_active Ceased
- 2022-01-06 EP EP22753098.7A patent/EP4291201A4/en active Pending
- 2022-01-06 BR BR112023015937A patent/BR112023015937A2/pt unknown
- 2022-01-06 US US18/276,527 patent/US20240173267A1/en active Pending
-
2024
- 2024-06-05 US US18/735,095 patent/US20240366518A1/en active Pending
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