JP2024507986A5 - - Google Patents

Info

Publication number
JP2024507986A5
JP2024507986A5 JP2023552183A JP2023552183A JP2024507986A5 JP 2024507986 A5 JP2024507986 A5 JP 2024507986A5 JP 2023552183 A JP2023552183 A JP 2023552183A JP 2023552183 A JP2023552183 A JP 2023552183A JP 2024507986 A5 JP2024507986 A5 JP 2024507986A5
Authority
JP
Japan
Prior art keywords
antibody
antibody fragment
use according
fragment
region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023552183A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024507986A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2022/055080 external-priority patent/WO2022184676A1/en
Publication of JP2024507986A publication Critical patent/JP2024507986A/ja
Publication of JP2024507986A5 publication Critical patent/JP2024507986A5/ja
Pending legal-status Critical Current

Links

JP2023552183A 2021-03-01 2022-03-01 抗体関連型移植拒絶反応の治療に使用するための抗cd38抗体 Pending JP2024507986A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21159860 2021-03-01
EP21159860.2 2021-03-01
PCT/EP2022/055080 WO2022184676A1 (en) 2021-03-01 2022-03-01 Anti-cd38 antibodies for use in the treatment of antibody-mediated transplant rejection

Publications (2)

Publication Number Publication Date
JP2024507986A JP2024507986A (ja) 2024-02-21
JP2024507986A5 true JP2024507986A5 (cg-RX-API-DMAC10.html) 2025-03-07

Family

ID=74844778

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023552183A Pending JP2024507986A (ja) 2021-03-01 2022-03-01 抗体関連型移植拒絶反応の治療に使用するための抗cd38抗体

Country Status (12)

Country Link
US (1) US20240228654A9 (cg-RX-API-DMAC10.html)
EP (1) EP4301779A1 (cg-RX-API-DMAC10.html)
JP (1) JP2024507986A (cg-RX-API-DMAC10.html)
KR (1) KR20230154239A (cg-RX-API-DMAC10.html)
AU (1) AU2022230717A1 (cg-RX-API-DMAC10.html)
BR (1) BR112023016352A2 (cg-RX-API-DMAC10.html)
CA (1) CA3209172A1 (cg-RX-API-DMAC10.html)
CL (1) CL2023002495A1 (cg-RX-API-DMAC10.html)
IL (1) IL304692A (cg-RX-API-DMAC10.html)
MX (1) MX2023009868A (cg-RX-API-DMAC10.html)
TW (1) TW202302642A (cg-RX-API-DMAC10.html)
WO (1) WO2022184676A1 (cg-RX-API-DMAC10.html)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202545561A (zh) * 2024-01-16 2025-12-01 德商莫菲西斯有限責任公司 抗體的高度濃縮液體製劑

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020164788A1 (en) 1994-12-02 2002-11-07 The Wellcome Foundation Limited Humanized antibodies to CD38
AU770718B2 (en) 1998-06-05 2004-02-26 Mayo Foundation For Medical Education And Research Use of genetically engineered antibodies to CD38 to treat multiple myeloma
US7223397B1 (en) 1999-01-07 2007-05-29 Research Development Foundation Potentiation of anti-CD38-Immunotoxin cytotoxicity
EP1174440A1 (en) 2000-07-19 2002-01-23 U-BISys B.V. A selectively-expressed epitope on the human CD38 molecule detected by a phage display library-derived human scFv antibody fragment
EP2915820A1 (en) 2004-02-06 2015-09-09 MorphoSys AG Anti-CD38 human antibodies and uses therefor
EP2551282A3 (en) 2005-03-23 2013-02-13 Genmab A/S Antibodies against CD38 for treatment of multiple myeloma
TW200745162A (en) 2005-05-24 2007-12-16 Morphosys Ag Generation and profiling of fully human hucal gold-derived therapeutic antibodies specific for human CD38
CN101287764B (zh) 2005-10-12 2013-11-13 莫佛塞斯公司 特异性针对人CD38的完全人HuCAL GOLD-衍生治疗抗体的生成和鉴定
PL2081595T3 (pl) 2006-09-26 2019-11-29 Genmab As Anty-cd38 wraz z kortykosteroidami wraz ze środkiem chemioterapeutycznym niebędącym kortykosteroidem, do leczenia guzów nowotworowych
EP1914242A1 (en) 2006-10-19 2008-04-23 Sanofi-Aventis Novel anti-CD38 antibodies for the treatment of cancer
EP2191842A1 (en) 2008-11-28 2010-06-02 Sanofi-Aventis Antitumor combinations containing antibodies recognizing specifically CD38 and cytarabine
EP2191841A1 (en) 2008-11-28 2010-06-02 Sanofi-Aventis Antitumor combinations containing antibodies recognizing specifically CD38 and vincristine
EP2191840A1 (en) 2008-11-28 2010-06-02 Sanofi-Aventis Antitumor combinations containing antibodies recognizing specifically CD38 and melphalan
EP2191843A1 (en) 2008-11-28 2010-06-02 Sanofi-Aventis Antitumor combinations containing antibodies recognizing specifically CD38 and cyclophosphamide
US9732154B2 (en) 2014-02-28 2017-08-15 Janssen Biotech, Inc. Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia
PE20171094A1 (es) 2014-12-04 2017-08-07 Janssen Biotech Inc Anticuerpos anti-cd38 para el tratamiento de la leucemia linfoblastica aguda
EP3313441B1 (en) 2015-06-24 2024-02-21 Janssen Biotech, Inc. Immune modulation and treatment of solid tumors with antibodies that specifically bind cd38
WO2018002181A1 (en) 2016-06-28 2018-01-04 Umc Utrecht Holding B.V. TREATMENT OF IgE-MEDIATED DISEASES WITH ANTIBODIES THAT SPECIFICALLY BIND CD38
EP3434692A1 (en) 2017-07-24 2019-01-30 Encefa Compounds which specifically binds to cd38 for use in the treatment of neurodegenerative diseases
WO2020185672A1 (en) 2019-03-08 2020-09-17 Cedars-Sinai Medical Center Anti-cd38 agents for desensitization and treatment of antibody-mediated rejection of organ transplants
TWI924633B (zh) 2019-03-15 2026-05-11 德商莫菲西斯公司 用於治療自體抗體介導的自體免疫疾病的抗-cd38 抗體及其醫藥組成物

Similar Documents

Publication Publication Date Title
JP7771235B2 (ja) 抗-cd19抗体薬物複合体に関連する組成物および方法
JP2020019787A5 (cg-RX-API-DMAC10.html)
BR112021005868A2 (pt) Anticorpos anti-hla-g, composições compreendendo anticorpos anti-hla-g e métodos de uso de anticorpos anti-hla-g
JP2022515077A5 (cg-RX-API-DMAC10.html)
JP2020528768A5 (cg-RX-API-DMAC10.html)
BR112019016204A2 (pt) anticorpo ou fragmento de ligação a antígeno do anticorpo, polinucleotídeo, vetor, célula, imunócito artificial, métodos para produzir um anticorpo ou um fragmento de ligação a antígeno do anticorpo, para produzir uma molécula que se liga ao cd3 humano e cd3 de macaco cinomolgo e ao gprc5d humano, composição medicinal para tratamento e/ou prevenção, moléculas tendo atividade de ligação a antígeno e que se ligam ao cd3 humano e cd3 de macaco cinomolgo e ao gprc5d humano, e, usos para preparar um medicamento para tratar e/ou prevenir um câncer, para induzir citotoxicidade para as células expressando gprc5d e para redirecionamento de células t para as células expressando gprc5d
RU2018145852A (ru) Антитело против lag-3, его антигенсвязывающий фрагмент и их фармацевтическое применение
JP2021524256A5 (cg-RX-API-DMAC10.html)
JP2021510736A5 (cg-RX-API-DMAC10.html)
JP2020536109A5 (cg-RX-API-DMAC10.html)
TW202214697A (zh) 抗cd70抗體及其應用
US9156912B2 (en) Immunological reconstitution promoter or prophylactic agent for infections each of which maintains graft-versus-tumor effect
JP2024531151A5 (cg-RX-API-DMAC10.html)
JP2020528750A5 (cg-RX-API-DMAC10.html)
JP2021527640A5 (cg-RX-API-DMAC10.html)
RU2019139093A (ru) Фармацевтическая композиция на основе антитела к pd-l1 и ее применение
JP2025183307A5 (cg-RX-API-DMAC10.html)
JP2024520666A5 (cg-RX-API-DMAC10.html)
CA3108812A1 (en) Use of tim-3 antibody in preparation of medicines for treating tumors
JP2020513757A5 (cg-RX-API-DMAC10.html)
JP2024503784A5 (cg-RX-API-DMAC10.html)
JP2024540226A5 (cg-RX-API-DMAC10.html)
JP2024537284A5 (cg-RX-API-DMAC10.html)
JP2025509567A5 (cg-RX-API-DMAC10.html)
JP2025502061A5 (cg-RX-API-DMAC10.html)