JP2024507550A - Ｈｉｖ療法に有用な化合物 - Google Patents

Ｈｉｖ療法に有用な化合物 Download PDF

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Publication number
JP2024507550A
JP2024507550A JP2023550695A JP2023550695A JP2024507550A JP 2024507550 A JP2024507550 A JP 2024507550A JP 2023550695 A JP2023550695 A JP 2023550695A JP 2023550695 A JP2023550695 A JP 2023550695A JP 2024507550 A JP2024507550 A JP 2024507550A
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JP
Japan
Prior art keywords
mmol
dcm
amino
phenylalaninate
stirred
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2023550695A
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English (en)
Japanese (ja)
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JP2024507550A5 (https=
Inventor
ビー．ナラシムフル、ナイドゥ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ViiV Healthcare Co
Original Assignee
ViiV Healthcare Co
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Publication date
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Publication of JP2024507550A publication Critical patent/JP2024507550A/ja
Publication of JP2024507550A5 publication Critical patent/JP2024507550A5/ja
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
JP2023550695A 2021-02-23 2022-02-21 Ｈｉｖ療法に有用な化合物 Withdrawn JP2024507550A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163152356P 2021-02-23 2021-02-23
US63/152,356 2021-02-23
PCT/US2022/017134 WO2022182604A1 (en) 2021-02-23 2022-02-21 Compounds useful in hiv treatment

Publications (2)

Publication Number Publication Date
JP2024507550A true JP2024507550A (ja) 2024-02-20
JP2024507550A5 JP2024507550A5 (https=) 2025-03-05

Family

ID=80685329

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023550695A Withdrawn JP2024507550A (ja) 2021-02-23 2022-02-21 Ｈｉｖ療法に有用な化合物

Country Status (4)

Country Link
US (1) US20240182510A1 (https=)
EP (1) EP4298105A1 (https=)
JP (1) JP2024507550A (https=)
WO (1) WO2022182604A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4358968A4 (en) * 2021-06-22 2025-05-07 Rome Therapeutics, Inc. 4-ETHINYL-3-HYDROXY-TETRAHYDROFURANYL ADENINE PHOSPHORAMIDATE AND RELATED COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISEASES

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4107288A (en) 1974-09-18 1978-08-15 Pharmaceutical Society Of Victoria Injectable compositions, nanoparticles useful therein, and process of manufacturing same
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
EP1378509A4 (en) 2001-03-19 2009-03-25 Ono Pharmaceutical Co DRUGS WITH TRIAZASPIRO ç5.5] UNDECANDERIVATES AS ACTIVE SUBSTANCE
CA2502109C (en) 2004-03-24 2010-02-23 Yamasa Corporation 4'-c-substituted-2-haloadenosine derivative
CN104640444B (zh) * 2012-06-16 2016-12-14 河南美泰宝生物制药有限公司 双肝脏靶向氨基磷酸酯和氨基膦酸酯前药
CN113811360A (zh) * 2019-03-06 2021-12-17 葛兰素史密斯克莱知识产权（第2 号）有限公司 用于hiv治疗的化合物
WO2021188959A1 (en) * 2020-03-20 2021-09-23 Gilead Sciences, Inc. Prodrugs of 4'-c-substituted-2-halo-2'-deoxyadenosine nucleosides and methods of making and using the same

Also Published As

Publication number Publication date
WO2022182604A1 (en) 2022-09-01
US20240182510A1 (en) 2024-06-06
EP4298105A1 (en) 2024-01-03

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