JP2024504364A5 - - Google Patents
Info
- Publication number
- JP2024504364A5 JP2024504364A5 JP2023544292A JP2023544292A JP2024504364A5 JP 2024504364 A5 JP2024504364 A5 JP 2024504364A5 JP 2023544292 A JP2023544292 A JP 2023544292A JP 2023544292 A JP2023544292 A JP 2023544292A JP 2024504364 A5 JP2024504364 A5 JP 2024504364A5
- Authority
- JP
- Japan
- Prior art keywords
- membered
- alkyl
- group
- alkyls
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163140314P | 2021-01-22 | 2021-01-22 | |
| US63/140,314 | 2021-01-22 | ||
| PCT/US2022/013383 WO2022159746A1 (en) | 2021-01-22 | 2022-01-21 | Gcn2 modulating compounds and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024504364A JP2024504364A (ja) | 2024-01-31 |
| JP2024504364A5 true JP2024504364A5 (enExample) | 2025-01-28 |
Family
ID=80446635
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023544292A Pending JP2024504364A (ja) | 2021-01-22 | 2022-01-21 | Ｇｃｎ２をモジュレートする化合物およびその使用 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20240083897A1 (enExample) |
| EP (1) | EP4281182A1 (enExample) |
| JP (1) | JP2024504364A (enExample) |
| KR (1) | KR20240021143A (enExample) |
| CN (1) | CN117203206A (enExample) |
| AU (1) | AU2022210760A1 (enExample) |
| BR (1) | BR112023014723A2 (enExample) |
| CA (1) | CA3209124A1 (enExample) |
| CO (1) | CO2023010940A2 (enExample) |
| CR (1) | CR20230408A (enExample) |
| IL (1) | IL304611A (enExample) |
| MX (1) | MX2023008589A (enExample) |
| PE (1) | PE20240691A1 (enExample) |
| WO (1) | WO2022159746A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB202008749D0 (en) | 2020-06-09 | 2020-07-22 | Ip2Ipo Innovations Ltd | Novel compounds |
| WO2023230567A1 (en) * | 2022-05-25 | 2023-11-30 | Hibercell, Inc. | Gcn2 modulator for treating cancer |
| WO2024077092A1 (en) * | 2022-10-04 | 2024-04-11 | Hibercell, Inc. | Gcn2 inhibitor for treating metastases |
| IL322199A (en) * | 2023-01-20 | 2025-09-01 | Hibercell Inc | Crystalline forms of 6-(3-((5-chloro-2-methoxypyridine)-3-sulfonamido)-6,2-difluorophenyl)-N-methylimidazo[1, 5-A]pyrazine-1-carboxamide and methods of use are |
| WO2025122985A1 (en) * | 2023-12-08 | 2025-06-12 | Hibercell, Inc. | Methods of treating acute myeloid leukemia using combinations of gcn2 modulators, venetoclax, and azacitidine |
| WO2025137710A1 (en) * | 2023-12-22 | 2025-06-26 | Hibercell, Inc. | Methods of treating cancer using combinations of gcn2 modulators and belzutifan |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004279427B2 (en) * | 2003-10-08 | 2008-07-03 | Irm Llc | Compounds and compositions as protein kinase inhibitors |
| ES2422263T3 (es) * | 2008-12-19 | 2013-09-10 | Nerviano Medical Sciences Srl | Pirazoles bicíclicos como inhibidores de la proteinquinasa |
| HRP20241768T1 (hr) * | 2016-08-10 | 2025-02-28 | Takeda Pharmaceutical Company Limited | Heterociklički spoj |
| JP7229257B2 (ja) * | 2018-01-29 | 2023-02-28 | メルク パテント ゲーエムベーハー | Ｇｃｎ２阻害剤およびその使用 |
| US20220388964A1 (en) * | 2019-04-12 | 2022-12-08 | Hibercell, Inc. | (aza)indazolyl-aryl sulfonamide and related compounds and their use in treating medical conditions |
| JP2023514328A (ja) * | 2020-02-17 | 2023-04-05 | アレスタ・セラピューティクス・ベスローテン・フェンノートシャップ | Ｇｃｎ２モジュレーター化合物 |
-
2022
- 2022-01-21 BR BR112023014723A patent/BR112023014723A2/pt unknown
- 2022-01-21 KR KR1020237028260A patent/KR20240021143A/ko active Pending
- 2022-01-21 CA CA3209124A patent/CA3209124A1/en active Pending
- 2022-01-21 PE PE2023002158A patent/PE20240691A1/es unknown
- 2022-01-21 EP EP22704111.8A patent/EP4281182A1/en active Pending
- 2022-01-21 US US18/262,493 patent/US20240083897A1/en active Pending
- 2022-01-21 WO PCT/US2022/013383 patent/WO2022159746A1/en not_active Ceased
- 2022-01-21 MX MX2023008589A patent/MX2023008589A/es unknown
- 2022-01-21 JP JP2023544292A patent/JP2024504364A/ja active Pending
- 2022-01-21 CR CR20230408A patent/CR20230408A/es unknown
- 2022-01-21 AU AU2022210760A patent/AU2022210760A1/en active Pending
- 2022-01-21 CN CN202280022926.3A patent/CN117203206A/zh active Pending
-
2023
- 2023-07-20 IL IL304611A patent/IL304611A/en unknown
- 2023-08-22 CO CONC2023/0010940A patent/CO2023010940A2/es unknown
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