JP2024503924A5 - - Google Patents

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Publication number
JP2024503924A5
JP2024503924A5 JP2023545254A JP2023545254A JP2024503924A5 JP 2024503924 A5 JP2024503924 A5 JP 2024503924A5 JP 2023545254 A JP2023545254 A JP 2023545254A JP 2023545254 A JP2023545254 A JP 2023545254A JP 2024503924 A5 JP2024503924 A5 JP 2024503924A5
Authority
JP
Japan
Prior art keywords
immunoconjugate
seq
radioactive metal
antigen
binding domain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023545254A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024503924A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2022/050673 external-priority patent/WO2022162549A2/en
Publication of JP2024503924A publication Critical patent/JP2024503924A/ja
Publication of JP2024503924A5 publication Critical patent/JP2024503924A5/ja
Pending legal-status Critical Current

Links

JP2023545254A 2021-01-27 2022-01-26 カリクレイン関連ペプチダーゼ2抗原結合ドメインを含む免疫コンジュゲート及びその使用 Pending JP2024503924A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163142147P 2021-01-27 2021-01-27
US63/142,147 2021-01-27
US202163144586P 2021-02-02 2021-02-02
US63/144,586 2021-02-02
PCT/IB2022/050673 WO2022162549A2 (en) 2021-01-27 2022-01-26 Immunoconjugates comprising kallikrein related peptidase 2 antigen binding domains and their uses

Publications (2)

Publication Number Publication Date
JP2024503924A JP2024503924A (ja) 2024-01-29
JP2024503924A5 true JP2024503924A5 (https=) 2025-01-30

Family

ID=80447388

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023545254A Pending JP2024503924A (ja) 2021-01-27 2022-01-26 カリクレイン関連ペプチダーゼ2抗原結合ドメインを含む免疫コンジュゲート及びその使用

Country Status (9)

Country Link
US (1) US20250325718A1 (https=)
EP (1) EP4284446A2 (https=)
JP (1) JP2024503924A (https=)
KR (1) KR20230142482A (https=)
AU (1) AU2022213825A1 (https=)
CA (1) CA3205707A1 (https=)
IL (1) IL304656A (https=)
MX (1) MX2023008803A (https=)
WO (1) WO2022162549A2 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10806806B2 (en) 2016-06-23 2020-10-20 Cornell University Trifunctional constructs with tunable pharmacokinetics useful in imaging and anti-tumor therapies
CN109843339B (zh) 2016-06-23 2023-07-07 康奈尔大学 影响肿瘤杀伤的双重靶向构建体
JP7699542B2 (ja) 2018-11-20 2025-06-27 コーネル ユニバーシティー 放射線核種の大環状錯体およびがんの放射線療法におけるそれらの使用
BR112021022237A2 (pt) 2019-05-10 2022-03-29 Janssen Biotech Inc Queladores macrocíclicos e métodos de uso dos mesmos
BR112022001368A2 (pt) 2019-07-26 2022-05-24 Janssen Biotech Inc Proteínas que compreendem domínios de ligação ao antígeno de peptidase 2 relacionada à calicreína e seus usos
CA3240194A1 (en) * 2021-11-09 2023-05-19 Edward Cleator Macrocyclic compounds and methods of making the same
EP4469095A1 (en) * 2022-01-26 2024-12-04 Janssen Biotech, Inc. Immunoconjugates comprising kallikrein related peptidase 2 antigen binding domains and their uses

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6884869B2 (en) 2001-04-30 2005-04-26 Seattle Genetics, Inc. Pentapeptide compounds and uses related thereto
CA2478683C (en) * 2002-03-08 2016-01-26 Protein Design Labs, Inc. Antibodies against cancer antigen tmeff2 and uses thereof
DK1912677T3 (da) * 2005-06-20 2014-01-13 Psma Dev Company L L C PSMA-antistof-lægemiddel-konjugater
AU2008343589A1 (en) 2007-12-19 2009-07-09 Centocor Ortho Biotech Inc. Design and generation of human de novo pIX phage display libraries via fusion to pIX or pVII, vectors, antibodies and methods
ES2984483T3 (es) 2010-03-31 2024-10-29 Ablexis Llc Ingeniería genética de ratones para la producción de anticuerpos quiméricos
PT2931030T (pt) 2012-12-14 2020-08-03 Open Monoclonal Tech Inc Polinucleótidos que codificam anticorpos de roedores com idiótipos humanos e animais que os compreendem
SMT201900338T1 (it) * 2013-11-19 2019-07-11 Fredax Ab Anticopri anti-callicreina-2 umanizzato
WO2017087826A1 (en) 2015-11-18 2017-05-26 Memorial Sloan Kettering Cancer Center Systems, methods, and compositions for imaging androgen receptor axis activity in carcinoma, and related therapeutic compositions and methods
IL269763B2 (en) 2017-03-30 2024-08-01 Univ Cornell Macrocyclic complexes of alpha-emitting radionuclides and their use in targeted radiotherapy of cancer
JP7699542B2 (ja) 2018-11-20 2025-06-27 コーネル ユニバーシティー 放射線核種の大環状錯体およびがんの放射線療法におけるそれらの使用
BR112021022237A2 (pt) * 2019-05-10 2022-03-29 Janssen Biotech Inc Queladores macrocíclicos e métodos de uso dos mesmos
BR112022001368A2 (pt) * 2019-07-26 2022-05-24 Janssen Biotech Inc Proteínas que compreendem domínios de ligação ao antígeno de peptidase 2 relacionada à calicreína e seus usos
WO2021060350A1 (ja) 2019-09-27 2021-04-01 株式会社J-オイルミルズ 食肉加工品の製造方法

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