JP2024501831A5 - - Google Patents

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Publication number
JP2024501831A5
JP2024501831A5 JP2023538969A JP2023538969A JP2024501831A5 JP 2024501831 A5 JP2024501831 A5 JP 2024501831A5 JP 2023538969 A JP2023538969 A JP 2023538969A JP 2023538969 A JP2023538969 A JP 2023538969A JP 2024501831 A5 JP2024501831 A5 JP 2024501831A5
Authority
JP
Japan
Prior art keywords
nucleic acid
item
tcr
acid molecule
domain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023538969A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024501831A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/065069 external-priority patent/WO2022140665A1/en
Publication of JP2024501831A publication Critical patent/JP2024501831A/ja
Publication of JP2024501831A5 publication Critical patent/JP2024501831A5/ja
Pending legal-status Critical Current

Links

JP2023538969A 2020-12-23 2021-12-23 融合タンパク質を用いたtcrリプログラミングのための組成物及び方法 Pending JP2024501831A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202063129829P 2020-12-23 2020-12-23
US63/129,829 2020-12-23
US202163225821P 2021-07-26 2021-07-26
US63/225,821 2021-07-26
US202163250329P 2021-09-30 2021-09-30
US63/250,329 2021-09-30
US202163257345P 2021-10-19 2021-10-19
US63/257,345 2021-10-19
PCT/US2021/065069 WO2022140665A1 (en) 2020-12-23 2021-12-23 Compositions and methods for tcr reprogramming using fusion proteins

Publications (2)

Publication Number Publication Date
JP2024501831A JP2024501831A (ja) 2024-01-16
JP2024501831A5 true JP2024501831A5 (enExample) 2024-12-04

Family

ID=82160130

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023538969A Pending JP2024501831A (ja) 2020-12-23 2021-12-23 融合タンパク質を用いたtcrリプログラミングのための組成物及び方法

Country Status (6)

Country Link
US (1) US20240117002A1 (enExample)
EP (1) EP4267733A4 (enExample)
JP (1) JP2024501831A (enExample)
AU (1) AU2021410788A1 (enExample)
CA (1) CA3203180A1 (enExample)
WO (1) WO2022140665A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021226289A2 (en) * 2020-05-05 2021-11-11 TCR2 Therapeutics Inc. Compositions and methods for tcr reprogramming using cd70 specific fusion proteins
WO2024054425A1 (en) * 2022-09-08 2024-03-14 Cugene Inc. Novel pd1-targeted il-15 immunocytokine and vitokine fusions
KR20260024373A (ko) * 2023-05-05 2026-02-20 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 다중-수용체 자연 살해 세포

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6251570B2 (ja) * 2010-09-21 2017-12-20 アルター・バイオサイエンス・コーポレーション 多量体il−15可溶性融合分子並びにその製造及び使用方法
EP2997134B1 (en) * 2013-05-14 2020-06-24 Board of Regents, The University of Texas System Human application of engineered chimeric antigen receptor (car) t-cells
BR112019007100A2 (pt) * 2016-10-07 2019-06-25 Tcr2 Therapeutics Inc composições e métodos para reprogramação de receptores de célula t com o uso de proteínas de fusão
CN110177803A (zh) * 2016-11-22 2019-08-27 T细胞受体治疗公司 用于使用融合蛋白进行tcr重新编程的组合物和方法
WO2018232020A1 (en) * 2017-06-13 2018-12-20 TCR2 Therapeutics Inc. Compositions and methods for tcr reprogramming using fusion proteins
CN111556892A (zh) * 2017-12-08 2020-08-18 菲特治疗公司 使用增强的iPSC衍生的效应细胞的免疫疗法
WO2019160956A1 (en) * 2018-02-13 2019-08-22 Novartis Ag Chimeric antigen receptor therapy in combination with il-15r and il15
CA3093449A1 (en) * 2018-03-09 2019-09-12 TCR2 Therapeutics Inc. Compositions and methods for tcr reprogramming using fusion proteins
WO2019222275A2 (en) * 2018-05-14 2019-11-21 TCR2 Therapeutics Inc. Compositions and methods for tcr reprogramming using inducible fusion proteins
CN114206357A (zh) * 2019-03-22 2022-03-18 T细胞受体治疗公司 使用融合蛋白进行tcr重编程的组合物和方法
WO2021133959A2 (en) * 2019-12-24 2021-07-01 TCR2 Therapeutics Inc. Compositions and methods for gamma delta tcr reprogramming using fusion proteins
WO2021226289A2 (en) * 2020-05-05 2021-11-11 TCR2 Therapeutics Inc. Compositions and methods for tcr reprogramming using cd70 specific fusion proteins

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