JP2024501757A - 遺伝子組換え細胞の製造方法 - Google Patents

遺伝子組換え細胞の製造方法 Download PDF

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JP2024501757A
JP2024501757A JP2023540859A JP2023540859A JP2024501757A JP 2024501757 A JP2024501757 A JP 2024501757A JP 2023540859 A JP2023540859 A JP 2023540859A JP 2023540859 A JP2023540859 A JP 2023540859A JP 2024501757 A JP2024501757 A JP 2024501757A
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rna
protein
sequence
ligand binding
cells
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ランボルン，ジョン
ポレッカ，インマコラータ
スミス，アマンダ
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ホライズン・ディスカバリー・リミテッド
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    • C12N15/90—Stable introduction of foreign DNA into chromosome
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JP2023540859A 2021-01-05 2022-01-05 遺伝子組換え細胞の製造方法 Pending JP2024501757A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163133942P 2021-01-05 2021-01-05
US202163133945P 2021-01-05 2021-01-05
US63/133,942 2021-01-05
US63/133,945 2021-01-05
GBGB2107188.1A GB202107188D0 (en) 2021-05-19 2021-05-19 Method for producing genetically modified cells
GB2107188.1 2021-05-19
PCT/GB2022/050004 WO2022148955A1 (en) 2021-01-05 2022-01-05 Method for producing genetically modified cells

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JP2024501757A true JP2024501757A (ja) 2024-01-15
JP2024501757A5 JP2024501757A5 (https=) 2024-12-23

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EP (1) EP4274893B1 (https=)
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CA (1) CA3207144A1 (https=)
WO (1) WO2022148955A1 (https=)

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US11970719B2 (en) * 2017-11-01 2024-04-30 The Regents Of The University Of California Class 2 CRISPR/Cas compositions and methods of use
WO2020051562A2 (en) 2018-09-07 2020-03-12 Beam Therapeutics Inc. Compositions and methods for improving base editing
EP3847254A4 (en) 2018-09-07 2022-08-10 Beam Therapeutics Inc. COMPOSITIONS AND METHODS FOR DELIVERING A NUCLEOBASE EDITING SYSTEM
AU2020215730A1 (en) 2019-01-31 2021-07-29 Beam Therapeutics Inc. Nucleobase editors having reduced non-target deamination and assays for characterizing nucleobase editors
CN120174005A (zh) 2019-02-13 2025-06-20 比姆医疗股份有限公司 具有用于修饰靶标序列中核碱基的腺苷脱氨酶碱基编辑器的经修饰的免疫细胞
EP4034138A4 (en) 2019-09-27 2024-07-31 Beam Therapeutics, Inc. COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIQUID CANCERS
CA3196831A1 (en) 2020-09-25 2022-03-31 Beam Therapeutics Inc. Fratricide resistant modified immune cells and methods of using the same
AU2024270764A1 (en) 2023-05-15 2025-12-04 Nchroma Bio, Inc. Compositions and methods for epigenetic regulation of hbv gene expression
WO2024240138A1 (zh) * 2023-05-22 2024-11-28 江西农业大学 基于perv逆转录酶的先导编辑系统
CN121100181A (zh) * 2023-05-26 2025-12-09 正序(上海)生物医药科技有限公司 基因编辑系统及其用途

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US20240067954A1 (en) 2024-02-29
EP4274893B1 (en) 2025-01-01
CA3207144A1 (en) 2022-07-14
EP4274893A1 (en) 2023-11-15

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