JP2024500250A - Covid-19の治療のためのdsg2組成物及び方法 - Google Patents

Covid-19の治療のためのdsg2組成物及び方法 Download PDF

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Publication number
JP2024500250A
JP2024500250A JP2023560254A JP2023560254A JP2024500250A JP 2024500250 A JP2024500250 A JP 2024500250A JP 2023560254 A JP2023560254 A JP 2023560254A JP 2023560254 A JP2023560254 A JP 2023560254A JP 2024500250 A JP2024500250 A JP 2024500250A
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JP
Japan
Prior art keywords
dsg2
isolated polypeptide
covid
protein
domain
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Pending
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JP2023560254A
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English (en)
Japanese (ja)
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JP2024500250A5 (enExample
Inventor
イン フー、シー
エドワード タイラー、ライアン
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Arvada Therapeutics Inc
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Arvada Therapeutics Inc
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Publication of JP2024500250A publication Critical patent/JP2024500250A/ja
Publication of JP2024500250A5 publication Critical patent/JP2024500250A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2023560254A 2020-12-15 2021-12-15 Covid-19の治療のためのdsg2組成物及び方法 Pending JP2024500250A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063125583P 2020-12-15 2020-12-15
US63/125,583 2020-12-15
US202163274715P 2021-11-02 2021-11-02
US63/274,715 2021-11-02
PCT/US2021/063433 WO2022132854A1 (en) 2020-12-15 2021-12-15 Dsg2 compositions and methods for the treatment of covid-19

Publications (2)

Publication Number Publication Date
JP2024500250A true JP2024500250A (ja) 2024-01-05
JP2024500250A5 JP2024500250A5 (enExample) 2024-11-29

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ID=79425717

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JP2023560254A Pending JP2024500250A (ja) 2020-12-15 2021-12-15 Covid-19の治療のためのdsg2組成物及び方法

Country Status (9)

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EP (1) EP4263588A1 (enExample)
JP (1) JP2024500250A (enExample)
KR (1) KR20230120141A (enExample)
AU (1) AU2021400845A1 (enExample)
CA (1) CA3202364A1 (enExample)
IL (1) IL303444A (enExample)
MX (1) MX2023006704A (enExample)
TW (1) TW202237634A (enExample)
WO (1) WO2022132854A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2024005327A (es) * 2021-11-02 2024-05-21 Arvada Therapeutics Inc Composiciones y metodos de dsg2.
CN116458893A (zh) * 2023-04-19 2023-07-21 电子科技大学 一种covid-19后心肌缺血的早期筛查方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190353652A1 (en) * 2017-01-13 2019-11-21 The Hospital For Sick Children Method for Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100316347B1 (ko) 1998-09-15 2002-08-27 한미약품(주) 대장균엔테로톡신ⅱ신호펩티드의변형체와인체성장호르몬의융합단백질을발현하는재조합미생물및그를이용한인체성장호르몬의제조방법
DE10057397A1 (de) 2000-11-18 2002-05-23 Hella Kg Hueck & Co Vorrichtung zur Ölstandsmessung
US20100303723A1 (en) * 2006-11-20 2010-12-02 Massachusetts Institute Of Technology Drug delivery systems using fc fragments

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190353652A1 (en) * 2017-01-13 2019-11-21 The Hospital For Sick Children Method for Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
"Fusion protein linkers: Property, design and functionality", ADVANCED DRUG DELIVERY REVIEWS, vol. 65, JPN6025041653, 2012, pages 1357 - 1369, ISSN: 0005818127 *

Also Published As

Publication number Publication date
AU2021400845A1 (en) 2023-07-13
CA3202364A1 (en) 2022-06-23
EP4263588A1 (en) 2023-10-25
WO2022132854A1 (en) 2022-06-23
TW202237634A (zh) 2022-10-01
MX2023006704A (es) 2023-06-20
KR20230120141A (ko) 2023-08-16
IL303444A (en) 2023-08-01

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